Protein
MCA_01626_1
Length
1,455 amino acids
Gene name: SSN2
Description: Mediator of RNA polymerase II transcription subunit 13
Browser: contigA:5007945-5012426+
RNA-seq: read pairs 930, FPKM 7.9, percentile rank 22.1% (100% = highest expression)
Protein function
| Annotation: | SSN2 | Mediator of RNA polymerase II transcription subunit 13 | |
|---|---|---|---|
| KEGG: | K15165 | SSN2 | mediator of RNA polymerase II transcription subunit 13, fungi type |
| EGGNOG: | 0PGJE | SSN2 | Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II- dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex |
| SGD closest match: | S000002851 | SSN2 | Mediator of RNA polymerase II transcription subunit 13 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00257_1 | 38.22% | 1222 | 0.0 | MIA_00257_1 |
| UniRef50_A0A1E3PV09 | 30.38% | 530 | 1e-65 | Uncharacterized protein n=1 Tax=Lipomyces starkeyi NRRL Y-11557 TaxID=675824 RepID=A0A1E3PV09_LIPST |
| A0A161HGX7_9ASCO | 28.94% | 501 | 5e-62 | Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_2690 PE=4 SV=1 |
| A0A060T1Q2_BLAAD | 27.54% | 552 | 1e-54 | ARAD1A01980p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A01980g PE=4 SV=1 |
| SSN2_YARLI | 29.37% | 378 | 4e-41 | Mediator of RNA polymerase II transcription subunit 13 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=SSN2 PE=3 SV=3 |
| A0A1E4TKI1_9ASCO | 27.78% | 360 | 1e-35 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_42867 PE=4 SV=1 |
| SSN2_YEAST | 22.54% | 346 | 2e-12 | Mediator of RNA polymerase II transcription subunit 13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SSN2 PE=1 SV=2 |
| A0A1E3PI44_9ASCO | 39.34% | 61 | 5e-09 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83169 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0114
Protein family membership
- Mediator complex, subunit Med13 (IPR009401)
Domains and repeats
None predicted.
Detailed signature matches
-
-
PF06333 (Med13_C)
-
no IPR
Unintegrated signatures
-
mobidb-lite (disord...)
Protein sequence
>MCA_01626_1 MSFNLDEAKSNLFLAGNFSQIPYQVFISPNPNDNRSILFQAECTIRKKLPNVLVKVHGHELWLFSINSTQLKFSSKDLFG LTETSTGIFIPSMIYQNDRAFPPPYIPFINSVRALIFNTTSCNESFVPFGSDVLINKFNGKLLHIDPLLLPNGDLILKAY YQPSNFVKFTSSSFEKTNISPTKVIIAPVGAEALFLSTAKVSPSVTNSFLQVFESFYPYKFDIQQTTFKEWGDFKFTSLD SHFLWPLDLCFCWQNTNADNLDKALRWFRADDVISEVENQMTGLQSLIFTEEATEENSSNEVAGKFSTSLPYLSGDLDKP TEFSNRGPNQLTDQQQTARLSTNSMYPTPPDPTVKARTETETEGSASWNTPGPASDHWADLDEELFGDEQEITEDDFNFF DEPQDKPEERNPTHPNSSQTPYSNDNINWNNTTGSNQYPDNRNGSKVPESHSTLNNSTQASHNNTFISNMINSSLKGANS SASDTNFSPLVFDASISDQLDSKYSKGGRFFVSPENFEDNDDEESEDSDNDSINDQENTEKDNKLIYKESTTKSAMTSPD FRKSIDETGSISLKRKLDESTLMDPQDDTDKIDKQKINDWINAFTQASFFSSHSSAIALQAPTAIKASDTLSFEGAIETI IDQIVWDNGLFSNLLDTYEAFEYPDLSLFPVIDSVFPDIRRLTLLETAKEANLELTLDTDNTSKSMQISKSETKIASLPP FPASRATSSDDLKIRPSSEGQKVILPPTPTSSNNTTISKQIPKNDLFIQFQLQPPHYSVIRMEQILKATSPIVRFWKVFG LEPCYGKKNMTSLILFPGIKGIFKSSLYFMQTLKTAYEGSSLGEMQFFQNKTITDGLVPFFYNGTSPESALEGMRLAFIS LGRELKLLEKKPKTLLILIANPFPGISSLMTFSQAFTQIKKEYLSSVMSVDGKEEQHDIVMQIIPIDFFSSTDTLISPSQ YRMVQLALSLYDKCSIAGEGIIYKTNPMPLTMNTQRRCPAYLISHMAPKSIKFKYSEVPSPSIFDEDSFLHFCYTVSEDR RWLICSWSDQYGEISKVEAFCLAKIGGQIRVFEEVCSEVWQKTISLISHSPVQWKLTLAKLGHIDDDELNMWKGFLRSCN KVTSAYILTVDLYPTLVIKGKLDAPVSDPKEECTTDNINNKDNNNSNGSNNNNNNNSNNNNNSNNKESSSMSNISKLSGV TGHGTTAGHYDLPPSIPSIPNLPSRPQHQHQQTSTKKNEDNNNNNSMNGKNSNYLLGGSGSGVGGTSNSGDSFVLSKDNF GQSINDSVLIDTKNNVFGMVFKRQQFSQQQTATSTTTSSVSTTAQSSSSSSASSSTPTAAAASSSSSSSLLVTKPFNYAS LLSSTSSSLSVFKLRPSISGYLIKYDESSSQQNIFEATLLYSPTPFEPCIKMILEQYRNLSSLATTTGVGSRTGVAAPWH VLAVDKVQRVVINIF
GO term prediction
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
Molecular Function
GO:0001104 RNA polymerase II transcription cofactor activity
Cellular Component
GO:0016592 mediator complex