Protein

MIA_00133_1

Length
460 amino acids


Browser: contig01:367305-368688-

Protein function

EGGNOG:0PGE1SUB7Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity (By similarity)
SGD closest match:S000005529YSP3Subtilisin-like protease 3
CGD closest match:CAL0000199552PRB1Prb1p

Protein alignments

%idAln lengthE-value
MCA_03837_158.12%4990.0MCA_03837_1
A0A0J9XHJ8_GEOCN53.60%4036e-144Similar to Saccharomyces cerevisiae YOR003W YSP3 Putative to the subtilisin-like protease III OS=Geotrichum candidum GN=BN980_GECA17s00296g PE=3 SV=1
UniRef50_A0A0J9XHJ853.60%4031e-140Similar to Saccharomyces cerevisiae YOR003W YSP3 Putative to the subtilisin-like protease III n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XHJ8_GEOCN
A0A060T1Y8_BLAAD44.19%3871e-102ARAD1A03322p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A03322g PE=3 SV=1
A0A167DJQ7_9ASCO42.60%3926e-102Proteinase B OS=Sugiyamaella lignohabitans GN=PRB1 PE=3 SV=1
A0A1E3PH86_9ASCO43.08%3901e-96Subtilisin-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47354 PE=3 SV=1
Q6C486_YARLI36.36%3962e-61YALI0E28875p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E28875g PE=3 SV=1
Q59Z57_CANAL32.03%4622e-59Prb1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRB1 PE=3 SV=1
YSP3_YEAST35.59%3405e-58Subtilisin-like protease 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YSP3 PE=2 SV=2
A0A1E4THC1_9ASCO35.93%3986e-43Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_65053 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7643
Predicted cleavage: 25

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 460

Detailed signature matches

Residue annotation

  1. calcium binding si...
  2. active site cd04077
  3. catalytic triad cd...
  4. calcium binding si...

Protein sequence

>MIA_00133_1
MKLSVTLSSMAMAWRCLVHLAAASPLVAEFEASFPTDAAIAPEKDALELLPRDQTADIAESPNGKQAGNSNLLQDYIVIL
KDETGQTLARRSAHRAWLDELLSKRQSLNARDAQPAPPPIDFDSTADVEASKAIMGYHGAFTEAEIKAIASSEDVAFVER
ESYDTIQQDFVYVQYNTPWGLGRISHKSFDSPAGTDDATYVFGSQGGANTTLYVLDSGVRADHVEFTGRVRWGANYIDNE
QTDVHGHGTHISGIAAGHNVGVAKFANIVAVKVIDADRRAAISNIIKGVQWIIDDAAANPGSRAVINYSAVGVISDARTL
AIQKAVDAGIMVVTAAGNSAADACSYGPANMAASTDGVLTVAALNYTNTPADFSNYGGCVSVYAPGVSILSASKDAVNSY
KYMSGTSMSSPYVAGLAAYFWSINSGYSLSDVKSAILNYNDGQIVDAVGNTANKIAYNHQ

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004252 serine-type endopeptidase activity

Cellular Component

None predicted.