Protein
MIA_00018_1
Length
473 amino acids
Browser: contig01:41320-42742+
Protein function
| EGGNOG: | 0PFUR | ERG4 | )-reductase |
|---|---|---|---|
| SGD closest match: | S000002980 | ERG4 | Delta(24(24(1)))-sterol reductase |
| CGD closest match: | CAL0000199354 | ERG4 | Delta(24(24(1)))-sterol reductase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_05643_1 | 71.308% | 474 | 0.0 | MCA_05643_1 |
| A0A0J9XAZ3_GEOCN | 65.895% | 475 | 0.0 | Similar to Saccharomyces cerevisiae YGL012W ERG4 C-24(28) sterol reductase OS=Geotrichum candidum GN=BN980_GECA07s03442g PE=4 SV=1 |
| A0A167EQY0_9ASCO | 67.338% | 447 | 0.0 | Delta(24(24(1)))-sterol reductase OS=Sugiyamaella lignohabitans GN=ERG4 PE=4 SV=1 |
| A0A060THR7_BLAAD | 65.022% | 446 | 0.0 | ARAD1D39996p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D39996g PE=4 SV=1 |
| ERG4_YEAST | 55.983% | 468 | 2.20e-179 | Delta(24(24(1)))-sterol reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG4 PE=1 SV=2 |
| UniRef50_P25340 | 55.983% | 468 | 5.25e-176 | Delta(24(24(1)))-sterol reductase n=55 Tax=Ascomycota TaxID=4890 RepID=ERG4_YEAST |
| A0A1E4TG65_9ASCO | 54.468% | 470 | 7.03e-179 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2426 PE=4 SV=1 |
| A0A1E3PQ03_9ASCO | 54.622% | 476 | 4.86e-172 | ERG4/ERG24 ergosterol biosynthesis protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49810 PE=4 SV=1 |
| Q6C8J1_YARLI | 56.651% | 436 | 7.34e-172 | YALI0D19206p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D19206g PE=4 SV=1 |
| A0A1D8PJ25_CANAL | 50.418% | 478 | 3.26e-167 | Delta(24(24(1)))-sterol reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ERG4 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0388
Predicted cleavage: 14
Protein family membership
- Ergosterol biosynthesis ERG4/ERG24 (IPR001171)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MIA_00018_1 MTEKQTSTVTSRSAPSKEPSLPPRKIFDPTVQYGTFHYEFGGPIGVSAMMIGFPLLMWYLWASYKFYDCHLASPRADQSL VDFVKELAHHVYTDAYPTRTAWAIIWGFLIFQAVNYLTLPGIWTEGLPIPQNKNRGLKYYCNAVYSLYFSTVVALALHFS GIFSLATIIDRFGEIMSVAIISGFLISFAVFVRALLEKKQVRMTGNWAYDFFMGAPLYPRVGPLLDLKMFFEVRLPWFTL YFLALSACFKQYKEYGYVSFQMIHCFLGAWLYANACAKGEELIIPSWDIFYEKFGFMLIFWNIAGVPYTYCHNTLYLVSH DPATYHHSPLYNAFVLVLLLGAYYFFDTTNGQKNAFRQQIAGTYKPRNTFPRLPYLVVKNPRYIKCKNGGTLLADGWYKY ARKAHYTADFLQNLSWALNCGSGSFLPYFYPTFFFFMILHRAQRDEEKCAQKYGDDWVEYKKQCPYVFIPGVY
GO term prediction
Biological Process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
Cellular Component
GO:0016020 membrane