Protein

MIA_00002_1

Length
847 amino acids

Browser: contig01:3172-5716+

Protein function

EGGNOG:0QDZFReverse transcriptase (RNA-dependent DNA polymerase)
SGD closest match:S000007354TY2B-OR1Transposon Ty2-OR1 Gag-Pol polyprotein

Protein alignments

%idAln lengthE-value
UniRef50_A0A085ND4037.135%3426.44e-44Uncharacterized protein n=2 Tax=Trichuris TaxID=36086 RepID=A0A085ND40_9BILA
MCA_03512_137.097%1241.02e-16MCA_03512_1
A0A161HJI4_9ASCO31.013%1583.45e-16Gag-pol fusion protein OS=Sugiyamaella lignohabitans GN=AWJ20_4398 PE=4 SV=1
YO21B_YEAST26.897%2902.38e-12Transposon Ty2-OR1 Gag-Pol polyprotein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TY2B-OR1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0003

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 847

Detailed signature matches

  1. Domain IPR001878
    Zinc finger, CCHC-type
    1. G3DSA:4.10.60.10
    2. SM00343 (c2hcfinal6)
    3. SSF57756 (Retroviru...)
    4. PS50158 (ZF_CCHC)
  2. Domain IPR025724
    GAG-pre-integrase domain
    1. PF13976 (gag_pre-in...)
  3. Domain IPR012337
    Ribonuclease H-like domain
    1. SSF53098 (Ribonucle...)
    2. G3DSA:3.30.42...
  4. Domain IPR001584
    Integrase, catalytic core
    1. PF00665 (rve)
    2. PS50994 (INTEGRASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)
  5. mobidb-lite (disord...)

Protein sequence

>MIA_00002_1
MNNGVHLYVEAGTVSPGPNESLDDLTASLDTVVHDVILNNISPELIEQVNDVAIRGRDLWLYLHQEYSQLQPADVISLMK
SLYAVNIESGPKLVSSIRTHVATWRSIYQSLSPDSVVAFNILASMSPNCERLIQYALEHRFDGNNADNLDINNFVRNADK
WAKLLKLTGSPATLSTEAFSASSKRHGNRSRNNVLTCFRCKKRGHTSNRCPASWDEAQAAQQDKDKDDKESKDGKSSRAW
FAEAVDGFTQIVDDDSFVSYAFESKTSDVCEKFGIDCSESDDDSESELFDSSEPNNGDEDYFDYQVSESCSNSELDVVPA
ADPFLGCTEDPCFVSEPCVGSGVDPCDPESFIGSPIVSFVPEPLVGSDDGVCLPCFDFLVDPVVDPSPCDIICLADPAVD
PCSSVVDSLVDSVVEPFPSDVTSLADPTVDPCSFDIDSMADPIVDPSSSVTHPTDTKKSRLSPLLYLFVFAFLLLSLILL
VLLHLFPFLDSRQSVHQAFVAESAASAEAHLVVGPDTFDFIHDTGATSHICNNISYFTNLRPTSTTIRGLGSSSAKAVGD
IIVDVLGQDGNPFDRVVLRDVLYVPNIPRNLFAARRAIAGGCQFIENLDHISAVENGTTRVHAIAMGDLYFCRFRVVLPS
KPVHEVFAVEPSANLWHQRLGHASVEVLKKLSKSLSVKPTHFEVVDSHKCDACLGGKATSLPFTGTTEKATRPLELLMSD
LSGPHVATPVGHRYVLTIMDFYSRYSYVELLVKKSDASLAIRNYIARCESYFSGDSRGNRVSYFHSDNGGEYISKDLEQF
FVSKGIKHTFTVPHTPQQNGVAERLNRTLFEKAKSMLLYSHAPDICG

GO term prediction

Biological Process

GO:0015074 DNA integration

Molecular Function

GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

Cellular Component

None predicted.