Protein
MCA_06494_1
Length
455 amino acids
Gene name: TUB2B
Description: Tubulin beta chain
Browser: contigD:4387954-4389583+
RNA-seq: read pairs 7775, FPKM 210.7, percentile rank 88.7% (100% = highest expression)
Protein function
| Annotation: | TUB2B | Tubulin beta chain | |
|---|---|---|---|
| KEGG: | K07375 | TUBB | tubulin beta |
| EGGNOG: | 0PIDE | TUB2 | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain |
| SGD closest match: | S000001857 | TUB2 | Tubulin beta chain |
| CGD closest match: | CAL0000176403 | TUB2 | Tubulin beta chain |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| TBB2_GEOCN | 85.37% | 417 | 0.0 | Tubulin beta-2 chain OS=Geotrichum candidum PE=3 SV=2 |
| MIA_02273_1 | 83.89% | 422 | 0.0 | MIA_02273_1 |
| A0A060TBL7_BLAAD | 82.38% | 420 | 0.0 | Tubulin beta chain OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D32890g PE=3 SV=1 |
| Q6C4G6_YARLI | 76.13% | 419 | 0.0 | Tubulin beta chain OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E26961g PE=3 SV=1 |
| A0A1E3PQU8_9ASCO | 75.60% | 414 | 0.0 | Tubulin beta chain OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_20588 PE=3 SV=1 |
| A0A1E4TC50_9ASCO | 69.00% | 442 | 0.0 | Tubulin beta chain OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3974 PE=3 SV=1 |
| UniRef50_P68371 | 65.14% | 416 | 0.0 | Tubulin beta-4B chain n=276 Tax=Eukaryota TaxID=2759 RepID=TBB4B_HUMAN |
| TBB_YEAST | 65.87% | 416 | 0.0 | Tubulin beta chain OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TUB2 PE=1 SV=2 |
| A0A1D8PC97_CANAL | 65.14% | 416 | 0.0 | Tubulin beta chain OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TUB2 PE=3 SV=1 |
| A0A167FK53_9ASCO | 83.23% | 316 | 0.0 | Tubulin beta chain OS=Sugiyamaella lignohabitans GN=TUB2 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.2426
Protein family membership
- Tubulin (IPR000217)
- Beta tubulin (IPR002453)
Domains and repeats
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Domain
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Domain
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Domain
1
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100
150
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250
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455
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
cd02187 (beta_tubulin)
Residue annotation
-
nucleotide binding...
-
Taxol binding site...
-
alpha/beta domain ...
-
beta/alpha domain ...
Protein sequence
>MCA_06494_1 MWSSSNQISTAFWNTITEEHKLDKDGYLSGKEEEYSSQRIDVFFSEASNRKYVPRAVAVDLEPATLDAIRSGPLGHIYRP DNLISGESGAGNNWAKGFYTEGAELMDPVMDVIRREAEQSDSLQGFQLAHSLGGGTGSGLGTLLLTRIREEYPDRMLSTY SVLPSPKLSDTVTEPYNAVLSFNQLVDHSDATYCLDNEALFDICENTLKITRPSHTDLNNLIALVMSGVTTCLRYPGQLN GDLRKLAVNLVPFPRLHFFTAGFAPLFSKNSKSFQNLAVPELTQQLFNPSNIMAACDPFHGKYLTISTIFRGDVAMKEVE DAIMTAKNKYSPYFVEWIPNNVQTSVCNVPPKGLTRSATFIANSTAVQELFSRTSDQFNAMFRRKAFLHWYTGEGMEAAE FEEAQSNLTDLILEYQQYQNAGIDDEIMDEEYMMDEQQALQEGEYMEQDLAQEDM
GO term prediction
Biological Process
GO:0007017 microtubule-based process
Molecular Function
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
Cellular Component
GO:0005874 microtubule