MCA_06373_1
Gene name: NAM2
Description: Leucine--tRNA ligase, mitochondrial
Browser: contigD:4015293-4018101+
RNA-seq: read pairs 1497, FPKM 19.8, percentile rank 41.1% (100% = highest expression)
Protein function
| Annotation: | NAM2 | Leucine--tRNA ligase, mitochondrial | |
|---|---|---|---|
| KEGG: | K01869 | LARS | leucyl-tRNA synthetase [EC:6.1.1.4] |
| EGGNOG: | 0PHW1 | NAM2 | Leucyl-tRNA synthetase |
| SGD closest match: | S000004374 | NAM2 | Leucine--tRNA ligase, mitochondrial |
| CGD closest match: | CAL0000195709 | NAM2 | Leucine--tRNA ligase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00818_1 | 61.38% | 914 | 0.0 | MIA_00818_1 |
| A0A0J9XFB9_GEOCN | 60.56% | 890 | 0.0 | Similar to Saccharomyces cerevisiae YLR382C NAM2 Mitochondrial leucyl-tRNA synthetase OS=Geotrichum candidum GN=BN980_GECA13s02617g PE=3 SV=1 |
| UniRef50_A0A0J9XFB9 | 60.56% | 890 | 0.0 | Similar to Saccharomyces cerevisiae YLR382C NAM2 Mitochondrial leucyl-tRNA synthetase n=4 Tax=saccharomyceta TaxID=716545 RepID=A0A0J9XFB9_GEOCN |
| A0A167BZV4_9ASCO | 55.28% | 919 | 0.0 | Leucine--tRNA ligase NAM2 OS=Sugiyamaella lignohabitans GN=NAM2 PE=3 SV=1 |
| A0A060T578_BLAAD | 55.49% | 892 | 0.0 | ARAD1C09834p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C09834g PE=3 SV=1 |
| Q6C363_YARLI | 54.74% | 813 | 0.0 | YALI0F02299p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F02299g PE=3 SV=1 |
| A0A1D8PQ56_CANAL | 50.57% | 876 | 0.0 | Leucine--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NAM2 PE=3 SV=1 |
| SYLM_YEAST | 47.93% | 868 | 0.0 | Leucine--tRNA ligase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NAM2 PE=1 SV=1 |
| A0A1E4TL37_9ASCO | 43.99% | 898 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22053 PE=3 SV=1 |
| A0A1E3PFH9_9ASCO | 51.60% | 593 | 0.0 | YLR382Cp-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84018 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9937
Predicted cleavage: 22
Protein family membership
- Leucine-tRNA ligase (IPR002302)
Domains and repeats
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Domain
-
Domain
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Domain
Detailed signature matches
no IPR
Residue annotation
-
active site cd00812
-
HIGH motif cd00812
-
KMSKS motif cd00812
Protein sequence
>MCA_06373_1 MACTLLRYPRLAAKQSLLIRSQPKLHSRLTQCSYLHSSSVLKARPELTTQQLDAKWKQIWDKSPSRKQLPLKPDGSIVPS KGKYFALSMFPYPSGMLHIGHLRVYTIIDVLARYRRMNGYEVINPMGWDSFGLPAENAAIERGIDPEDWTLSNIEKMKEQ MNLMFADFDWEREVVTCSPEYYKWTQKLFLMMYEAGLAYRKDSLVNWDPVDKTVLANEQVDANGRSWRSGAVVEHKMLEQ WFLKITDYAQELHQDLQLLKQWPDNVKIMQRNWIGGSTGARIKFDLKGAGDSIKELEAFTTRPDTLFGVQYVAISLNHEI AKKAAKSDPELAKFLETAKNLPEDTKAGYKLKDITVSNPLFPGEFSIPVFVAPYVIGDYGYGTVMGCPGHDTRDFDFWKE NMPGEPIIETITPPPDYTYPNGVSIYFKKDGTLNENCGPYKGLDSRTGGEKIVKDLMTSGKAHFETQWKLRDWLISRQRF WGAPIPIIHCDSCGTVPVPDEQLPVLLPKHLNGPLSTSEEFVNTSCPSCGGHAKRDTDTMDTFMDSSWYIFRYTDPKNTE LIFDPKKASELMPVDLYVGGVEHAILHLLYFRFISKFLHKNGNWNGGNMNGEPIKQLLTQGMVQGKTNIDPDSGKFLKKE EVDFTNPHDPKVKATGKPCIVKYEKMSKSKYNGASPEECIQKHGADATRAHILFQAPVSDVLNWDENQISGVKRWLNRVT KFTTTLSEMIEKEAESSSSKDEYLAKIIKDSQNLQFEKLNPAEQNVWAGIQSSIKQITDALHKDFTLNTLISDYMKLSNL ILTPLDSKKSKISVPVSLYSITQFLKLISPVVPVHAEDNWEFIQKTLQPGKEWTSIFAESWPEPQFVPNLNNGRFVVLVN GKRKLMLSGPKSAQGDVNKILELVKADTEGKAFLETNRIKDTVLAKDFVINIITE
GO term prediction
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006429 leucyl-tRNA aminoacylation
Molecular Function
GO:0000166 nucleotide binding
GO:0002161 aminoacyl-tRNA editing activity
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004823 leucine-tRNA ligase activity
GO:0005524 ATP binding
Cellular Component
None predicted.