Protein
MCA_06353_1
Length
352 amino acids
Browser: contigD:3966500-3967559+
RNA-seq: read pairs 2033, FPKM 71.2, percentile rank 73.0% (100% = highest expression)
Protein function
| EGGNOG: | 0PJT2 | GRE2 | NADPH-dependent methylglyoxal reductase GRE2 |
|---|---|---|---|
| SGD closest match: | S000002949 | YDR541C | Putative uncharacterized oxidoreductase YDR541C |
| CGD closest match: | CAL0000189861 | GRP2 | Putative NADPH-dependent methylglyoxal reductase GRP2 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9XCC0_GEOCN | 64.52% | 341 | 2e-157 | Similar to Saccharomyces cerevisiae YGL157W ARI1 NADPH-dependent aldehyde reductase OS=Geotrichum candidum GN=BN980_GECA07s05433g PE=4 SV=1 |
| UniRef50_A0A0J9XB22 | 61.88% | 341 | 2e-144 | Similar to Saccharomyces cerevisiae YGL157W ARI1 NADPH-dependent aldehyde reductase n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XB22_GEOCN |
| MIA_04276_1 | 60.35% | 343 | 5e-148 | MIA_04276_1 |
| A0A1E3PJ87_9ASCO | 43.52% | 347 | 5e-90 | NAD(P)-binding protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83062 PE=4 SV=1 |
| A0A060T4V0_BLAAD | 43.27% | 342 | 3e-88 | ARAD1B02860p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B02860g PE=4 SV=1 |
| Q6C9S0_YARLI | 43.45% | 336 | 4e-85 | YALI0D08844p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D08844g PE=4 SV=1 |
| GRP2_CANAL | 39.24% | 344 | 2e-84 | Putative NADPH-dependent methylglyoxal reductase GRP2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GRP2 PE=1 SV=2 |
| A0A167C177_9ASCO | 42.03% | 345 | 9e-84 | Carbonyl reductase (NADPH-dependent) OS=Sugiyamaella lignohabitans GN=AWJ20_3889 PE=4 SV=1 |
| YD541_YEAST | 43.53% | 340 | 2e-82 | Putative uncharacterized oxidoreductase YDR541C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YDR541C PE=3 SV=2 |
| A0A1E4T9D1_9ASCO | 39.71% | 350 | 2e-73 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_4495 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.6647
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
50
100
150
200
250
300
352
Detailed signature matches
no IPR
Unintegrated signatures
-
-
cd05227 (AR_SDR_e)
Residue annotation
-
NADP binding site ...
-
putative substrate...
-
active site cd05227
Protein sequence
>MCA_06353_1 MSTTISHSKVLVTGGSGFVATHVIDLLLKRGYKVKTTVRSQEKADYLAKKFDNKNLEFSIVPDIQAEDAFDETLKSDKDI TAVIHTASPFFTAKADLLNELLNPAIKGTTNILKAIKTYAPQVNTVIITSSYAAISNTAKRNDPTFIHTEETWADVTMEE ATTDLTKAYRGSKKFAEKAFWEFIETNKPNFTGTTVNPPMIYGPLLQQVKSIDELNTSSKFLWDASAESDPAQDPTDKYA KDLNLWVDVRDVAFAHVAPLENKKLAGKRLFVTPGYYSDQMVLDIANKTFPELQGKIAKGKPGTGSDFIDTVTKFDNHVT NELLGIEYIPFEQTVIDTYKSVLAIDDNKTKI
GO term prediction
Biological Process
GO:0006694 steroid biosynthetic process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Cellular Component
None predicted.