Protein
MCA_06275_1
Length
500 amino acids
Browser: contigD:3739990-3741493-
RNA-seq: read pairs 4691, FPKM 115.7, percentile rank 81.1% (100% = highest expression)
Protein function
| KEGG: | K01372 | BLMH | bleomycin hydrolase [EC:3.4.22.40] |
|---|---|---|---|
| EGGNOG: | 0PGMG | FG08736.1 | bleomycin hydrolase |
| SGD closest match: | S000005183 | LAP3 | Cysteine proteinase 1, mitochondrial |
| CGD closest match: | CAL0000187653 | LAP3 | Bleomycin hydrolase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_05709_1 | 72.80% | 500 | 0.0 | MIA_05709_1 |
| A0A0J9XIB3_GEOCN | 57.06% | 510 | 0.0 | Similar to Saccharomyces cerevisiae YNL239W LAP3 Cysteine aminopeptidase with homocysteine-thiolactonase activity OS=Geotrichum candidum GN=BN980_GECA20s00296g PE=4 SV=1 |
| A0A167FWM4_9ASCO | 53.72% | 497 | 0.0 | Lap3p OS=Sugiyamaella lignohabitans GN=LAP3 PE=4 SV=1 |
| A0A060TEG4_BLAAD | 53.89% | 475 | 0.0 | ARAD1D14938p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D14938g PE=4 SV=1 |
| UniRef50_K0KE56 | 45.63% | 515 | 2e-164 | Bleomycin hydrolase n=28 Tax=Saccharomycetales TaxID=4892 RepID=K0KE56_WICCF |
| Q5A6L5_CANAL | 51.10% | 454 | 9e-165 | Bleomycin hydrolase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LAP3 PE=4 SV=1 |
| Q6C2Q6_YARLI | 48.29% | 468 | 4e-162 | YALI0F05940p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F05940g PE=4 SV=1 |
| A0A1E4TGU8_9ASCO | 43.34% | 473 | 7e-143 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_115187 PE=4 SV=1 |
| BLH1_YEAST | 38.60% | 456 | 4e-113 | Cysteine proteinase 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LAP3 PE=1 SV=3 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1285
Protein family membership
- Peptidase C1B, bleomycin hydrolase (IPR004134)
Domains and repeats
None predicted.
Detailed signature matches
-
-
PF03051 (Peptidase_...)
-
PIRSF005700 (PepC)
-
cd00585 (Peptidase_C1B)
-
-
-
PS00139 (THIOL_PROT...)
-
no IPR
Unintegrated signatures
-
-
-
SSF54001 (Cysteine ...)
-
mobidb-lite (disord...)
Residue annotation
-
trimer interface c...
-
active site cd00585
-
G bulge cd00585
Protein sequence
>MCA_06275_1 MGNAPSTSQYVRPRQYYATSTNEKDQARETASEKLTNDLGRLVLSSKTRATDLSNPISIDGLGEWSEDIFSDPKNCLAQS AITKCAITDVIKDPKVFKNDAIHVFSEKIAFEGSPVTNQKSSGRCWLFSSTSLLRIGVQTRLKIDEFQLSQSYLFFYDKL EKCNYFMQNMIETADLDLDDRLITALLADDCSDGGQWDFLINIVEKYGLVPRSVFPESFNSENSGRLDYIISNKIREYGL LLRKAKSEKDAEISVLAALKEKFVQEIYAILCISLGTPPKPTDIIEWKYTDSDGKYHLMKMSPLAFYKDVVKFDVPNYFS LIHDPRNPYDALYTVDRNNNMQGGKPLEFVNAPINVLKQAAITAIQNNEAVFFGSDVGKFCDYATGTMDTEGWNYELAFN TSFNLSKAERVKLGLSQMTHAMLLTAVDLVDGKPVKWRVMNSWGTDVGDKGYFTMSDKWFDEFVYQVVTCPKYIGKKYTD IWKSKDYKVLPRWDPYGSLA
GO term prediction
Biological Process
GO:0006508 proteolysis
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
Cellular Component
None predicted.