Protein

MCA_06206_1

Length
118 amino acids


Gene name: TOP3A

Description: DNA topoisomerase 3

Browser: contigD:3558595-3559017+

RNA-seq: read pairs 37, FPKM 3.8, percentile rank 15.5% (100% = highest expression)

Protein function

Annotation:TOP3ADNA topoisomerase 3
EGGNOG:0PJ78TOP3DNA Topoisomerase
SGD closest match:S000004224TOP3DNA topoisomerase 3
CGD closest match:CAL0000178060orf19.5934DNA topoisomerase

Protein alignments

%idAln lengthE-value
UniRef50_A0A0L0SRU742.55%943e-14DNA topoisomerase n=1 Tax=Allomyces macrogynus ATCC 38327 TaxID=578462 RepID=A0A0L0SRU7_ALLMA
MIA_01657_154.17%727e-17MIA_01657_1
Q5ANG9_CANAL42.86%911e-14DNA topoisomerase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5934 PE=3 SV=1
TOP3_YEAST42.31%781e-14DNA topoisomerase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TOP3 PE=1 SV=1
A0A0J9XKM4_GEOCN45.95%746e-14DNA topoisomerase OS=Geotrichum candidum GN=BN980_GECA24s00087g PE=3 SV=1
A0A060T6F5_BLAAD41.79%678e-13DNA topoisomerase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B11726g PE=3 SV=1
A0A161HHI9_9ASCO41.33%751e-12DNA topoisomerase OS=Sugiyamaella lignohabitans GN=TOP3 PE=3 SV=1
A0A1E4TD21_9ASCO47.76%672e-11DNA topoisomerase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_140658 PE=3 SV=1
Q6C0R0_YARLI38.27%812e-09DNA topoisomerase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F22495g PE=3 SV=1
A0A1E3PHR5_9ASCO46.30%542e-09DNA topoisomerase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_70460 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0098

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 20 40 60 80 100 118

Detailed signature matches

    1. PF01751 (Toprim)
    2. PS50880 (TOPRIM)
    1. SSF56712 (Prokaryot...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd01028 (TOPRIM_TopoIA)

Residue annotation

  1. putative metal-bin...
  2. active site cd01028
  3. interdomain intera...
  4. nucleotide binding...

Protein sequence

>MCA_06206_1
MISITLFLNEIDALWQVDPSLLFNTRLKTIVPDSNKDLVSNIQAESRNADYLYIWTNNDREGEHIGYEILDAARKTNPRL
TDEYVKRTRKSTISLQKLFIKKLKNIISIVCCNIILTV

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.