Protein

MCA_06170_1

Length
724 amino acids


Gene name: FRE3D

Description: Ferric reductase transmembrane component 3

Browser: contigD:3440606-3442781+

RNA-seq: read pairs 2478, FPKM 42.2, percentile rank 61.5% (100% = highest expression)

Protein function

Annotation:FRE3DFerric reductase transmembrane component 3
EGGNOG:0PHSNFG01789.1Ferric-chelate reductase
SGD closest match:S000005908FRE3Ferric reductase transmembrane component 3
CGD closest match:CAL0000192959FRE3Fre3p

Protein alignments

%idAln lengthE-value
MIA_05199_143.34%7130.0MIA_05199_1
A0A0J9XI25_GEOCN35.26%7263e-146Similar to Saccharomyces cerevisiae YOR384W FRE5 Putative ferric reductase with similarity to Fre2p OS=Geotrichum candidum GN=BN980_GECA16s00164g PE=4 SV=1
UniRef50_A0A0J9XI2535.26%7267e-143Similar to Saccharomyces cerevisiae YOR384W FRE5 Putative ferric reductase with similarity to Fre2p n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XI25_GEOCN
Q6CET4_YARLI34.52%6462e-116YALI0B13134p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B13134g PE=4 SV=1
A0A167FY66_9ASCO31.50%7112e-102Fre2p OS=Sugiyamaella lignohabitans GN=FRE2 PE=4 SV=1
A0A060SVU5_BLAAD34.30%5542e-97ARAD1A00286p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A00286g PE=4 SV=1
A0A1E3PIN1_9ASCO28.67%7081e-90Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83263 PE=4 SV=1
A0A1D8PMF4_CANAL29.88%5691e-80Fre3p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=FRE3 PE=4 SV=1
A0A1E4TLJ4_9ASCO27.80%6332e-73Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30726 PE=4 SV=1
FRE3_YEAST27.87%6352e-67Ferric reductase transmembrane component 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FRE3 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4076

Protein family membership

None predicted.

Domains and repeats

1 100 200 300 400 500 600 724

Detailed signature matches

    1. PF01794 (Ferric_reduct)
    1. PS51384 (FAD_FR)
    1. PF08022 (FAD_binding_8)
    1. PF08030 (NAD_binding_6)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SFLDG01168 (Ferric_...)
  2. SFLDS00052 (Ferric_...)
  3. SSF52343 (Ferredoxi...)
  4. TRANSMEMBRANE (Tran...)
  5. cd06186 (NOX_Duox_l...)

Residue annotation

  1. FAD binding pocket...
  2. FAD binding motif ...
  3. beta-alpha-beta st...
  4. NAD pyrophosphate ...
  5. NAD binding pocket...
  6. NADP ribose bindin...

Protein sequence

>MCA_06170_1
MNYPKILLLFFTVFISSAFATKSQDALFRSCIEALKPYNFQCASEYAMGKGLRISRCQCWSPEYIASFYECAKETPGTKP
NEMGKAIRTMIYMCEKDNLRVGLTEHDVQHIYENGTRYFVNAEELGDPEHLLMHKVTIYTPVRLPTDVMAEYFHTCASWF
FTVYSGALFGGLIFLAYFGFVLVCGMIANFTKRVFPKQVKSIANSSLVLKFRGKIAYPALFGYRHSVPFKALGGFINMSV
PTRAQGVVLTGYFIMFIIFNFVKYEFFDNNRPFLGPAHQISRVIGDRTGIMASAHLPLIFLFAGRNNIMLTLTNWSYDTM
NVYHRWVSRGMYVLVVIHAISFTIAFKIEGYYESEFARSPNVWGITAGVCGGFMIFFAARTFRVNFYEWFLWFHRIMAIF
FICGMVYHTKTHSQSYNEFVWASVAIWVLDRFLRIIRIMASSVTAKAECKVYPEEIVKVKIDYSNFWGPSPGDYVFVYFM
KPVFGRWENHPFTTYPSPVPGEEKKLVMCIRAREGKTRQLHNYICNMPKREMSCHVLLDGPYGQRFPIENNDSILLIAGG
IGVTATYSYAAKLRALGERKQIIFLWTIRSLENLLFFKEELEFLLKDDRIQVQIFLSESSGSASPVINEKGTTDSSSPVP
IPINISSLNEKYGAEIPESFMSRVIYGRPNLPEIVHHHVSSTDGSSGVLVCGPPTMNDDVRAAVTKEINESKRQVDLYVE
AFNW

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.