Protein

MCA_06087_1

Length
356 amino acids


Browser: contigD:3211056-3212127-

RNA-seq: read pairs 4067, FPKM 140.8, percentile rank 84.2% (100% = highest expression)

Protein function

KEGG:K00872thrB1 homoserine kinase [EC:2.7.1.39]
EGGNOG:0PISCFG10211.1homoserine kinase
SGD closest match:S000001067THR1Homoserine kinase
CGD closest match:CAL0000196189THR1Homoserine kinase

Protein alignments

%idAln lengthE-value
MIA_04295_181.84%3580.0MIA_04295_1
A0A0J9X8T6_GEOCN78.92%3510.0Similar to Saccharomyces cerevisiae YHR025W THR1 Homoserine kinase, conserved protein required for threonine biosynthesis OS=Geotrichum candidum GN=BN980_GECA04s05939g PE=3 SV=1
A0A167F610_9ASCO76.62%3550.0Homoserine kinase OS=Sugiyamaella lignohabitans GN=THR1 PE=3 SV=1
Q6C1T8_YARLI76.12%3560.0YALI0F13453p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F13453g PE=3 SV=1
A0A060T8N9_BLAAD71.51%3514e-177ARAD1C38368p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C38368g PE=3 SV=1
KHSE_YEAST69.19%3573e-166Homoserine kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=THR1 PE=1 SV=4
UniRef50_P1742369.19%3578e-163Homoserine kinase n=349 Tax=Fungi TaxID=4751 RepID=KHSE_YEAST
A0A1E3PCM0_9ASCO67.22%3634e-166Homoserine kinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84377 PE=3 SV=1
A0A1E4TLW7_9ASCO65.82%3542e-153Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_92624 PE=3 SV=1
KHSE_CANAL58.07%3531e-132Homoserine kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=THR1 PE=3 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1746
Predicted cleavage: 13

Protein family membership

Domains and repeats

1 50 100 150 200 250 300 356

Detailed signature matches

    1. PIRSF000676 (Homose...)
    2. MF_00384 (Homoser_k...)
    1. SSF54211 (Ribosomal...)
    1. PF00288 (GHMP_kinas...)
    1. PF08544 (GHMP_kinas...)
    2. SSF55060 (GHMP Kina...)
    1. PS00627 (GHMP_KINAS...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PR00958 (HOMSERKINASE)

Protein sequence

>MCA_06087_1
MTRKFKISVPASSANIGPGFDVLGLALSLFLELTVTVDPSNTFDDDKTVTDNCKITYEGEGEENVPLLANQNLVTRVALY
VLKTNGLSSFPTGTHVHVNNPIPLGRGLGSSGAAVVAGVILGNEIGHLGFTKQRMLDYCLMIERHPDNITAAMMGGFVGS
YLRELSEADLSRVEIPLAEVLPEPAGGIETGLTPPEPPLNIGHHIKYDWCKSIKAICIVPSFEVSTAKSREVLPTAYTKK
DLVFNLQRLAVLTTALTQSPPNPELIFAAMQDRIHQPYRKVLIPGLSEILASMTPKTHPGLLGICLSGAGPTILALATDD
FENIASEIISHFKSKKIECKWKLLEPAYDGAQVTQL

GO term prediction

Biological Process

GO:0006566 threonine metabolic process

Molecular Function

GO:0004413 homoserine kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.