MCA_05994_1

Protein

Length

513 amino acids

Browser: contigD:2982044-2983606+

RNA-seq: read pairs 8, FPKM 0.2, percentile rank 4.7% (100% = highest expression)

Protein function

EGGNOG:	0PFT2	FG01986.1	transporter
SGD closest match:	S000003492	TNA1	High-affinity nicotinic acid transporter
CGD closest match:	CAL0000180798	TNA1	Tna1p

Protein alignments

	%id	Aln length	E-value
MIA_01233_1	62.55%	510	0.0	MIA_01233_1
UniRef50_G9MR46	37.00%	473	1e-108	Uncharacterized protein n=72 Tax=Fungi TaxID=4751 RepID=G9MR46_HYPVG
A0A0J9XA89_GEOCN	35.50%	476	4e-109	Similar to Saccharomyces cerevisiae YGR260W TNA1 High affinity nicotinic acid plasma membrane permease OS=Geotrichum candidum GN=BN980_GECA06s04619g PE=4 SV=1
A0A1E3PD75_9ASCO	33.86%	502	1e-107	MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_29178 PE=4 SV=1
Q6C581_YARLI	32.60%	497	2e-101	YALI0E20273p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E20273g PE=4 SV=1
A0A1E4TA06_9ASCO	30.21%	480	1e-83	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_125438 PE=4 SV=1
A0A060SZZ6_BLAAD	33.91%	407	1e-79	ARAD1C12562p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C12562g PE=4 SV=1
A0A167EMY7_9ASCO	28.79%	455	2e-62	Tna1p OS=Sugiyamaella lignohabitans GN=TNA1 PE=4 SV=1
A0A1D8PNL8_CANAL	27.36%	497	1e-52	Tna1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TNA1 PE=4 SV=1
TNA1_YEAST	25.26%	475	5e-50	High-affinity nicotinic acid transporter OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TNA1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1609
Predicted cleavage: 21

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
41 - 513
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 513

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  59 - 439
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  294 - 513
  
  PROSITE profiles
  PS50850 (MFS)
2. SSF103473 (MFS gene...)
  
  41 - 481
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
3. cd06174 (MFS)
  
  54 - 474
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

113 - 118

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

352 - 362

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

476 - 513

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 44

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

170 - 180

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

235 - 288

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

412 - 422

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

42 - 251

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

279 - 479

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

313 - 331

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

67 - 88

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

445 - 455

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

201 - 211

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

140 - 144

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

383 - 387

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

422 - 444

TMHMM
TMhelix (TMhelix)

454 - 476

TMHMM
TMhelix (TMhelix)

180 - 202

TMHMM
TMhelix (TMhelix)

212 - 234

TMHMM
TMhelix (TMhelix)

388 - 410

TMHMM
TMhelix (TMhelix)

145 - 167

TMHMM
TMhelix (TMhelix)

295 - 317

TMHMM
TMhelix (TMhelix)

119 - 141

TMHMM
TMhelix (TMhelix)

332 - 352

TMHMM
TMhelix (TMhelix)

90 - 112

TMHMM
TMhelix (TMhelix)

359 - 378

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

212 - 234

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

456 - 475

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

423 - 444

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

363 - 382

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

119 - 139

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

181 - 200

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

388 - 411

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

145 - 169

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

289 - 312

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

45 - 66

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

89 - 112

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

332 - 351

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

Residue annotation

putative substrate...

68Q

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

71I

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

72F

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

73T

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

76F

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

77D

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

94I

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

97C

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

98I

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

101Y

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

105A

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

106L

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

108S

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

109M

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

155E

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

156A

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

159I

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

160P

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

163S

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

164F

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

167S

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

179Q

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

180A

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

183L

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

184S

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

190N

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

306T

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

309N

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

310Y

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

313N

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

314I

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

317P

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

330I

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

334S

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

338Y

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

341A

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

345C

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

397S

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

400V

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

401H

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

404I

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

408I

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

409T

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

412S

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

424A

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

425L

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

428Q

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

429I

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

432G

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

433E

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

436G

putative substrate translocation pore
68Q, 71I, 72F, 73T, 76F, 77D, 94I, 97C, 98I, 101Y, 105A, 106L, 108S, 109M, 155E, 156A, 159I, 160P, 163S, 164F, 167S, 179Q, 180A, 183L, 184S, 190N, 306T, 309N, 310Y, 313N, 314I, 317P, 330I, 334S, 338Y, 341A, 345C, 397S, 400V, 401H, 404I, 408I, 409T, 412S, 424A, 425L, 428Q, 429I, 432G, 433E, 436G
CDD
cd06174 (MFS)

Protein sequence

>MCA_05994_1
MPISLPLSARRMLATVEQYEADKNDYHRPVEFECDHLKIEQENKLLLQVDLRILPAASLFVFLSLFDQGNIFTLEFDDMQ
KYISLQGSQFNHCIMVCIVAYGLFALPSMLCLIKTSPSFWLPTIISCWGVVMTTMGIIHDFSGLFWSRFFLGMFEAGMIP
GISFVISMWYRKNELQFRQAVILSVAISANAIGGVVSWTISLMKDVGGLEGWRWVFIIEGSLSVIVGGFGYLIMCNYPAN
TEILDEKSRMLIQSRVLAADGWDPEDALGDESETMYFFKKLKWNGLESAFLDWQVWLHTLVYFVITTGNYSINILLPRVL
QSMEFSPQGIKFVSIPVYIGASVTCILLAIISDKIASRSPVLILSFFMMICGFIVVLLSEVHDTRGSVAYSGIFLASVGV
HTAIPGSITWLSNNTMGSAKRIFALAIQIGFGELGGIVATYMYLNTNAAKTWGHSLMIIIACIGLLTVILLTFIYSRINR
QRELICASRGYIKVSNYELNLIGDKFPTFKYMS

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features