Protein
MCA_05891_1
Length
660 amino acids
Gene name: NOT4
Description: CCR4-NOT core ubiquitin-protein ligase subunit
Browser: contigD:2659878-2661861+
RNA-seq: read pairs 790, FPKM 14.8, percentile rank 33.7% (100% = highest expression)
Protein function
| Annotation: | NOT4 | CCR4-NOT core ubiquitin-protein ligase subunit | |
|---|---|---|---|
| KEGG: | K10643 | CNOT4 | CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] |
| EGGNOG: | 0PFB8 | NOT4 | complex. Subunit |
| SGD closest match: | S000000870 | MOT2 | General negative regulator of transcription subunit 4 |
| CGD closest match: | CAL0000188533 | NOT4 | CCR4-NOT core ubiquitin-protein ligase subunit |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_04532_1 | 75.08% | 329 | 8e-153 | MIA_04532_1 |
| A0A167DBS7_9ASCO | 85.60% | 243 | 6e-144 | CCR4-NOT core ubiquitin-protein ligase subunit MOT2 OS=Sugiyamaella lignohabitans GN=MOT2 PE=4 SV=1 |
| A0A0J9XHF3_GEOCN | 88.33% | 240 | 9e-142 | Similar to Saccharomyces cerevisiae YER068W MOT2 Subunit of the CCR4-NOT complex OS=Geotrichum candidum GN=BN980_GECA15s00054g PE=4 SV=1 |
| Q6C372_YARLI | 85.37% | 246 | 1e-140 | YALI0F02101p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F02101g PE=4 SV=1 |
| UniRef50_Q6C372 | 85.37% | 246 | 2e-137 | YALI0F02101p n=5 Tax=Saccharomycetales TaxID=4892 RepID=Q6C372_YARLI |
| A0A060T8J1_BLAAD | 80.99% | 242 | 2e-137 | ARAD1C29304p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C29304g PE=4 SV=1 |
| A0A1D8PSH4_CANAL | 70.04% | 247 | 1e-112 | CCR4-NOT core ubiquitin-protein ligase subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NOT4 PE=4 SV=1 |
| A0A1E3PKX2_9ASCO | 65.78% | 263 | 1e-111 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46621 PE=4 SV=1 |
| A0A1E4TF00_9ASCO | 70.61% | 245 | 3e-109 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2062 PE=4 SV=1 |
| NOT4_YEAST | 65.06% | 249 | 9e-102 | General negative regulator of transcription subunit 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MOT2 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0102
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Domain
1
100
200
300
400
500
600
660
Detailed signature matches
no IPR
Unintegrated signatures
-
-
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PF14570 (zf-RING_4)
-
SSF57850 (RING/U-box)
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cd16618 (mRING-HC-C...)
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mobidb-lite (disord...)
Residue annotation
-
Zn binding site cd...
-
polypeptide substr...
Protein sequence
>MCA_05891_1 MAFDQVDSFISDDEEELCPLCVEEMDISDKNFKPCPCGYQVCQFCYNNIRQNPQLNGLCPACRRPYDDESVEYRIISQEE WKMVHEKQARKERERKQRQREKKESEQSSRKHLSGMRVIQKNLVYVIGLNPNIPTEELHHTLRTDQFFGQYGKIQKIVIN RRTNANGNPGIGVYVTFARKEDAAKCIAAVDGSLNDGKYLRAAYGTTKYCSSYLRGQTCPNPNCMFLHEPGEEADSYTRQ DLSTFQVSGSSRDDDTISNASSTRSHKSSPPHHSASISKQHHHSNQHNSSSHDDSHSPSSPGDHSFHLPATVSWATKASP SPAQAKLHSSSTASSAYPPLPSAASHSTTDNHHDNTANASNNHNNTSNSHISSRPSSATSNSNHSTTSTKSDKPVVDESK YVPSPKPRSPDVAIELMNDFIISLANSDVLKSYEFTNTSAKSQKNAKPLPLFSYSQSTTNNNKTDSKKQSENKPDLKNLF NTDFASYLFKPCPASFAFRAKLEFFDNQIPDAMAQEQMLQQQYRLQQEQQQTLQAQQQRIQAYQLQMELNSSSTSTPPPP GLGPTNAQHVLPPQMQQQQSVNGGNALNFSGQNINSIFMAAAAANSSGILSNGSSVPSQSTTNNNSVNSSPVVNNAATNS QHSEELLARLYPKRDVKGMA
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding
Cellular Component
None predicted.