Protein

MCA_05883_1

Length
343 amino acids

Browser: contigD:2627258-2628290-

RNA-seq: read pairs 14173, FPKM 509.1, percentile rank 94.3% (100% = highest expression)

Protein function

EGGNOG:0PJT2GRE2NADPH-dependent methylglyoxal reductase GRE2
SGD closest match:S000003007YGL039WPutative uncharacterized oxidoreductase YGL039W
CGD closest match:CAL0000179051orf19.5611Methylglyoxal reductase (NADPH-dependent)

Protein alignments

%idAln lengthE-value
A0A0J9XC84_GEOCN37.11%3183e-58Similar to Saccharomyces cerevisiae YOL151W GRE2 3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase) OS=Geotrichum candidum GN=BN980_GECA09s01297g PE=4 SV=1
UniRef50_A0A0J9XBS435.50%3381e-53Similar to Saccharomyces cerevisiae YDR541C Putative dihydrokaempferol 4-reductase n=5 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XBS4_GEOCN
Q5ABT9_CANAL34.21%3426e-46Methylglyoxal reductase (NADPH-dependent) OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5611 PE=4 SV=1
A0A1E3PEB1_9ASCO32.87%2869e-44NAD(P)-binding protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_71947 PE=4 SV=1
MIA_05298_130.79%3542e-43MIA_05298_1
Q6C9C1_YARLI30.65%3361e-42YALI0D12386p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D12386g PE=4 SV=1
A0A060T5F8_BLAAD34.34%2655e-41ARAD1B04136p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B04136g PE=4 SV=1
A0A167C177_9ASCO31.45%3373e-41Carbonyl reductase (NADPH-dependent) OS=Sugiyamaella lignohabitans GN=AWJ20_3889 PE=4 SV=1
YGD9_YEAST31.70%3477e-36Putative uncharacterized oxidoreductase YGL039W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YGL039W PE=1 SV=1
A0A1E4T9D1_9ASCO29.49%2954e-28Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_4495 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6284
Predicted cleavage: 39

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 343

Detailed signature matches

  1. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  2. Domain IPR001509
    NAD-dependent epimerase/dehydratase
    1. PF01370 (Epimerase)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...

Protein sequence

>MCA_05883_1
MTKDTKTVFITGASGFVATWIVKNLVEKGYKVIGSVRSQAKGEYIAKFYTPESFEYVIVEDMTEQASIEKVYQDHPEIEY
VLHTASPISFTPKDQIKDVVEPAVNGLLAVVKATKAYGTNVKKLVFTSSIVAMLKSHNMLGNDPNFIYTEDTWSDIGIDF
VSNEVAGSGYLFSKGEAERKLWEFVKTETVPFAVSSLLLPFVFGAYPEGMISKPTQLASTSAIIYSWYKSIPEFDTLIPE
KTMASIGGSVKDIAELHVLTMVTPSTDNQRVLAFGFKYTQYDVVRCLKALAEGADKECNFNKLSAPVSGFDNSKTMAHFP
GFKFQTFEESIREIKIGFDKLES

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity
GO:0050662 coenzyme binding

Cellular Component

None predicted.