MCA_05773_1
Gene name: ADK1
Description: Adenylate kinase
Browser: contigD:2295880-2297290-
RNA-seq: read pairs 20795, FPKM 995.9, percentile rank 96.5% (100% = highest expression)
Protein function
Annotation: | ADK1 | Adenylate kinase | |
---|---|---|---|
KEGG: | K00939 | adk | adenylate kinase [EC:2.7.4.3] |
EGGNOG: | 0PG6Q | ADK1 | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways (By similarity) |
SGD closest match: | S000002634 | ADK1 | Adenylate kinase |
CGD closest match: | CAL0000198757 | ADK1 | Adenylate kinase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
A0A0J9X5J2_GEOCN | 84.98% | 253 | 2e-152 | Adenylate kinase OS=Geotrichum candidum GN=ADK1 PE=3 SV=1 |
MIA_04479_1 | 84.56% | 259 | 4e-152 | MIA_04479_1 |
A0A1E3PQN7_9ASCO | 78.63% | 248 | 6e-138 | Adenylate kinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=ADK1 PE=3 SV=1 |
KAD2_CANAL | 76.10% | 251 | 5e-136 | Adenylate kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ADK1 PE=3 SV=2 |
A0A060SYI1_BLAAD | 75.00% | 252 | 1e-132 | Adenylate kinase OS=Blastobotrys adeninivorans GN=ADK1 PE=3 SV=1 |
A0A167CDQ7_9ASCO | 73.62% | 254 | 1e-132 | Adenylate kinase OS=Sugiyamaella lignohabitans GN=ADK1 PE=3 SV=1 |
KAD2_YARLI | 74.80% | 254 | 1e-130 | Adenylate kinase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ADK1 PE=3 SV=2 |
UniRef50_B2CNY4 | 72.40% | 250 | 2e-125 | Adenylate kinase n=5 Tax=leotiomyceta TaxID=716546 RepID=KAD2_TALMA |
KAD2_YEAST | 78.70% | 216 | 2e-120 | Adenylate kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADK1 PE=1 SV=2 |
A0A1E4TJR4_9ASCO | 65.10% | 255 | 2e-116 | Adenylate kinase OS=Tortispora caseinolytica NRRL Y-17796 GN=ADK1 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0363
Protein family membership
- Adenylate kinase/UMP-CMP kinase (IPR000850)
- Adenylate kinase subfamily (IPR006259)
- Adenylate kinase 2 (IPR028587)
- Adenylate kinase subfamily (IPR006259)
Domains and repeats
-
Domain
-
Domain
Detailed signature matches
-
-
-
PF00406 (ADK)
Residue annotation
-
AMP-binding site c...
-
ATP-AMP (Ap5A)-bin...
Protein sequence
>MCA_05773_1 MTEIDEIKKIVHELKDKVLDLEAQLKAKAGLAPAVNVPKSIRMVLIGPPGAGKGTQAPNIKEKYCACHLATGDMLRSQVA KKTDLGLEAKKIMDQGGLVSDEIMVNMIKNELENNKECKNGFILDGFPRTIPQAERLDSMLAERKTPLQHAIELQIDDEL LVSRITGRLVHPASGRSYHRVFNPPKEDMKDDITGEPLVQRSDDNADALKKRLVTYHAQTAPVVKYYKKTGIWSGVDAAQ DPKDVWTSILKCFGDAK
GO term prediction
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006172 ADP biosynthetic process
Molecular Function
GO:0004017 adenylate kinase activity
GO:0005524 ATP binding
GO:0016776 phosphotransferase activity, phosphate group as acceptor
GO:0019205 nucleobase-containing compound kinase activity
Cellular Component
None predicted.