Protein

MCA_05769_1

Length
220 amino acids

Gene name: YPT52

Description: Rab family GTPase

Browser: contigD:2288065-2289147+

RNA-seq: read pairs 1706, FPKM 95.4, percentile rank 77.8% (100% = highest expression)

Protein function

Annotation:YPT52Rab family GTPase
KEGG:K07889RAB5C Ras-related protein Rab-5C
EGGNOG:0PG62YPT52gtp-binding protein
SGD closest match:S000005615VPS21Vacuolar protein sorting-associated protein 21
CGD closest match:CAL0000201225YPT52Rab family GTPase

Protein alignments

%idAln lengthE-value
MIA_05027_179.52%2107e-106MIA_05027_1
A0A167F051_9ASCO76.10%2055e-99Rab family GTPase VPS21 OS=Sugiyamaella lignohabitans GN=VPS21 PE=4 SV=1
A0A0J9XA10_GEOCN76.21%2064e-97Similar to Saccharomyces cerevisiae YKR014C YPT52 Endosomal Rab family GTPase OS=Geotrichum candidum GN=BN980_GECA06s04784g PE=4 SV=1
A0A060TBQ5_BLAAD69.90%2061e-93ARAD1D33902p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D33902g PE=4 SV=1
A0A1E4TFZ3_9ASCO78.61%1735e-92Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_108700 PE=4 SV=1
UniRef50_A0A162NLV981.98%1725e-87GTP-binding protein ypt5 n=4 Tax=leotiomyceta TaxID=716546 RepID=A0A162NLV9_9PEZI
A0A1E3PRR0_9ASCO81.18%1702e-90Ras-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81087 PE=4 SV=1
Q6C077_YARLI72.94%1704e-79YALI0F27181p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F27181g PE=4 SV=1
A0A1D8PFT9_CANAL55.45%2113e-69Rab family GTPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=YPT52 PE=4 SV=1
VPS21_YEAST59.76%1691e-62Vacuolar protein sorting-associated protein 21 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VPS21 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6415

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 220

Detailed signature matches

  1. Family IPR001806
    Small GTPase superfamily
    1. PF00071 (Ras)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR005225
    Small GTP-binding protein domain
    1. TIGR00231
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.70...
  2. G3DSA:3.40.50...
  3. PR00449 (RASTRNSFRMNG)
  4. PS51419 (RAB)
  5. SM00173 (ras_sub_4)
  6. SM00174 (rho_sub_3)
  7. SM00175 (rab_sub_5)
  8. SM00176 (ran_sub_2)
  9. cd01860 (Rab5_related)
  10. mobidb-lite (disord...)

Residue annotation

  1. Rab subfamily moti...
  2. G1 box cd01860
  3. GTP/Mg2+ binding s...
  4. Rab subfamily moti...
  5. Switch I region cd...
  6. putative GEF inter...
  7. G2 box cd01860
  8. Rab family motif 1...
  9. putative GDI inter...
  10. effector interacti...
  11. Rab family motif 2...
  12. G3 box cd01860
  13. Switch II region c...
  14. Rab family motif 3...
  15. Rab family motif 4...
  16. Rab family motif 5...
  17. Rab subfamily moti...
  18. G4 box cd01860
  19. G5 box cd01860
  20. Rab subfamily moti...

Protein sequence

>MCA_05769_1
MASATTPRSSTSSTRFAQFKLVLLGESAVGKSSIVERFAKNSFDDFRESTIGAAFLTQTIQLDSNTTVKFDIWDTAGQER
YKSLAPMYYRNANCAVVVYDLTQSASLARAKAWVKELQRQANENIVIALAGNKLDMAEESRQVEKEVAEAYAKEAGLLFF
ETSAKTGENIVELFTAIAKKLPVESVLSGGRGTGGGATGTRNQRGIDLKGPASGANACQC

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

None predicted.