Protein
MCA_05757_1
Length
149 amino acids
Gene name: GRX2
Description: Glutaredoxin-2, mitochondrial
Browser: contigD:2260060-2260788+
RNA-seq: read pairs 1194, FPKM 98.4, percentile rank 78.4% (100% = highest expression)
Protein function
| Annotation: | GRX2 | Glutaredoxin-2, mitochondrial | |
|---|---|---|---|
| KEGG: | K03676 | grxC | glutaredoxin 3 |
| EGGNOG: | 0PSDM | FG02097.1 | Glutaredoxin |
| SGD closest match: | S000002921 | GRX2 | Glutaredoxin-2, mitochondrial |
| CGD closest match: | CAL0000190988 | TTR1 | Dithiol glutaredoxin |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9X802_GEOCN | 50.00% | 96 | 6e-31 | Similar to Saccharomyces cerevisiae YCL035C GRX1 Glutathione-dependent disulfide oxidoreductase OS=Geotrichum candidum GN=BN980_GECA04s07512g PE=4 SV=1 |
| UniRef50_A0A0J9X802 | 50.00% | 96 | 1e-27 | Similar to Saccharomyces cerevisiae YCL035C GRX1 Glutathione-dependent disulfide oxidoreductase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X802_GEOCN |
| A0A1E3PE38_9ASCO | 44.74% | 114 | 3e-29 | Glutaredoxin OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_28651 PE=4 SV=1 |
| MIA_03049_1 | 40.68% | 118 | 9e-27 | MIA_03049_1 |
| A0A060T8Z1_BLAAD | 46.67% | 90 | 2e-25 | ARAD1C33550p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C33550g PE=4 SV=1 |
| Q5ABB1_CANAL | 45.16% | 93 | 6e-25 | Dithiol glutaredoxin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TTR1 PE=4 SV=1 |
| GLRX2_YEAST | 45.83% | 96 | 5e-23 | Glutaredoxin-2, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GRX2 PE=1 SV=3 |
| Q6CCY8_YARLI | 45.92% | 98 | 1e-22 | YALI0C05467p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C05467g PE=4 SV=1 |
| A0A167DUM9_9ASCO | 36.19% | 105 | 4e-17 | Dithiol glutaredoxin GRX2 OS=Sugiyamaella lignohabitans GN=GRX2 PE=4 SV=1 |
| A0A1E4TCR7_9ASCO | 35.80% | 81 | 4e-10 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_13921 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9976
Predicted cleavage: 19
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
20
40
60
80
100
120
149
Detailed signature matches
no IPR
Unintegrated signatures
-
-
SFLDG00328 (Glutare...)
-
cd03419 (GRX_GRXh_1...)
Residue annotation
-
GSH binding site c...
-
SFLDG00328
-
catalytic residues...
Protein sequence
>MCA_05757_1 MIAKILRPSPIFRNTVRNTGFLISRPIQLRTQMTAASANSIESLTDKSEIKSALQKLIDNNAVFLATKSYCPYCARAESL LSSLDIPFENLDLDLLRNGDKIQSVLFDMTTQSTVPNVFINQKHIGGNSDLQKLQQENKLLGMVSKSKL
GO term prediction
Biological Process
GO:0045454 cell redox homeostasis
Molecular Function
GO:0009055 electron carrier activity
GO:0015035 protein disulfide oxidoreductase activity
Cellular Component
None predicted.