Protein

MCA_05606_1

Length
112 amino acids


Gene name: GRX1

Description: Glutaredoxin-1

Browser: contigD:1786612-1786951-

RNA-seq: read pairs 7355, FPKM 804.2, percentile rank 96.0% (100% = highest expression)

Protein function

Annotation:GRX1Glutaredoxin-1
KEGG:K03676grxC glutaredoxin 3
EGGNOG:0PSDMGRX2Glutaredoxin
SGD closest match:S000000540GRX1Glutaredoxin-1
CGD closest match:CAL0000190988TTR1Dithiol glutaredoxin

Protein alignments

%idAln lengthE-value
UniRef50_C4R93451.35%1117e-25Cytoplasmic glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase n=31 Tax=cellular organisms TaxID=131567 RepID=C4R934_KOMPG
Q5ABB1_CANAL54.29%1054e-27Dithiol glutaredoxin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TTR1 PE=4 SV=1
A0A1E3PE38_9ASCO48.08%1041e-26Glutaredoxin OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_28651 PE=4 SV=1
MIA_01463_158.33%961e-25MIA_01463_1
Q6CCY8_YARLI52.94%1022e-25YALI0C05467p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C05467g PE=4 SV=1
A0A0J9X802_GEOCN45.71%1051e-24Similar to Saccharomyces cerevisiae YCL035C GRX1 Glutathione-dependent disulfide oxidoreductase OS=Geotrichum candidum GN=BN980_GECA04s07512g PE=4 SV=1
GLRX1_YEAST52.17%921e-24Glutaredoxin-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GRX1 PE=1 SV=1
A0A060TC62_BLAAD39.47%1143e-22ARAD1B20702p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B20702g PE=4 SV=1
A0A167DUM9_9ASCO34.91%1061e-13Dithiol glutaredoxin GRX2 OS=Sugiyamaella lignohabitans GN=GRX2 PE=4 SV=1
A0A1E4TCR7_9ASCO42.72%1038e-13Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_13921 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2900

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 20 40 60 80 100 112

Detailed signature matches

    1. SSF52833 (Thioredox...)
    1. PF00462 (Glutaredoxin)
    2. PS51354 (GLUTAREDOX...)
    1. PS00195 (GLUTAREDOX...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SFLDG00328 (Glutare...)
  2. cd03419 (GRX_GRXh_1...)

Residue annotation

  1. GSH binding site c...
  2. SFLDG00328
  3. catalytic residues...

Protein sequence

>MCA_05606_1
MSNAKQLVQDLIAGNTVFVASKSYCPYCTATKTLLLKTLGLKEKTDDGEDEDAVVKIIELDNRKDGAEIQRALYEITGQS
TVPNVFIKGKHIGGNSDLQALHSRGGVQQLLA

GO term prediction

Biological Process

GO:0045454 cell redox homeostasis

Molecular Function

GO:0009055 electron carrier activity
GO:0015035 protein disulfide oxidoreductase activity

Cellular Component

None predicted.