Protein
MCA_05581_1
Length
729 amino acids
Gene name: FRE2B
Description: Ferric/cupric reductase transmembrane component 2
Browser: contigD:1704586-1706776-
RNA-seq: read pairs 164, FPKM 2.8, percentile rank 13.3% (100% = highest expression)
Protein function
| Annotation: | FRE2B | Ferric/cupric reductase transmembrane component 2 | |
|---|---|---|---|
| EGGNOG: | 0PHSN | FG01789.1 | Ferric-chelate reductase |
| SGD closest match: | S000001703 | FRE2 | Ferric/cupric reductase transmembrane component 2 |
| CGD closest match: | CAL0000185898 | CFL4 | Ferric/cupric-chelate reductase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_05199_1 | 43.69% | 721 | 0.0 | MIA_05199_1 |
| A0A0J9XI25_GEOCN | 35.33% | 719 | 1e-147 | Similar to Saccharomyces cerevisiae YOR384W FRE5 Putative ferric reductase with similarity to Fre2p OS=Geotrichum candidum GN=BN980_GECA16s00164g PE=4 SV=1 |
| UniRef50_A0A0J9XI25 | 35.33% | 719 | 2e-144 | Similar to Saccharomyces cerevisiae YOR384W FRE5 Putative ferric reductase with similarity to Fre2p n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XI25_GEOCN |
| Q6CF26_YARLI | 32.97% | 743 | 3e-118 | YALI0B10846p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B10846g PE=4 SV=1 |
| A0A1E3PIN1_9ASCO | 29.06% | 726 | 1e-96 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83263 PE=4 SV=1 |
| A0A167FY66_9ASCO | 29.97% | 724 | 1e-95 | Fre2p OS=Sugiyamaella lignohabitans GN=FRE2 PE=4 SV=1 |
| A0A060SVU5_BLAAD | 32.57% | 568 | 2e-91 | ARAD1A00286p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A00286g PE=4 SV=1 |
| A0A1D8PN54_CANAL | 27.72% | 689 | 2e-78 | Ferric/cupric-chelate reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CFL4 PE=4 SV=1 |
| A0A1E4TLJ4_9ASCO | 28.98% | 597 | 2e-74 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30726 PE=4 SV=1 |
| FRE2_YEAST | 28.55% | 683 | 4e-66 | Ferric/cupric reductase transmembrane component 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FRE2 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.8415
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
600
729
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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-
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NON_CYTOPLASM... (N...)
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SFLDG01168 (Ferric_...)
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SFLDS00052 (Ferric_...)
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SIGNAL_PEPTIDE (Sig...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SSF52343 (Ferredoxi...)
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-
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TRANSMEMBRANE (Tran...)
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cd06186 (NOX_Duox_l...)
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mobidb-lite (disord...)
Residue annotation
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FAD binding pocket...
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FAD binding motif ...
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beta-alpha-beta st...
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NAD pyrophosphate ...
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NAD binding pocket...
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NADP ribose bindin...
Protein sequence
>MCA_05581_1 MKFSALLLLAAASTTLATSSRDPLMRTCNNFLGKLTFQCPEDKTKGGAKPRRSRVSKCSCQSPEYLASYADCIIQSKNQN QQKGFDTLLRTCGQPGMNPGLTQERIMDIYKNATDYFIDYDSVPMPKGNTRGGGGDKGGKGGKGGKEEKKNILYNPVRIP KKKLDLMNRSWASFYYNMYAGQLYGGILNAYFGFFLIAAMIMNFCKRVFPKQVHAASNIYIVKKFRQYIANPATCNQKHG VPGKWMYIINMSIPTRAQTIVVTGYWILFIIFNFIKYDVFEGSNVTLVRMIGDRTGIMSCAHLPLLFLFAGRNNILLYLT NWSYDTMSCYHRWVARGMYITAFIHSVTFTISYKNSGRYSVFSSPDIVWGIVATVLGAFILFFSLRHFREYTYEFFLLSH QIFVVFFLIGTLYHVLPFGYYEWVWATVGIWAFDRAARLAKIVISGLTSNAECQYYPESDVIKAKINYSEMWGASPGAYV YVYFLKPLWRCWENHPFSVYPSPVPGEEKKLVLCVRGREGWTRYISKFLAKQPNYFAKCPILLEGPYGQHFHLQHNDNIL LIGGGIGVTAVYSYVAKLRSQGQSKQITFVWLARSIEYLNFFRDEIESLLQSDDIQVHIYVSQKSNINTPSTDSLSDEKR DSSTPSIDNSSSEEKCGESIISSKVMSCVSYGRPDLSEVIHNTVSDSAGTTGVMVCGPPGMNDDVRKFVTAEMGVSKNVI DLYVEGFNW
GO term prediction
Biological Process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0016491 oxidoreductase activity
Cellular Component
None predicted.