Protein

MCA_05565_1

Length
246 amino acids

Browser: contigD:1660145-1660940+

RNA-seq: read pairs 2574, FPKM 128.8, percentile rank 82.8% (100% = highest expression)

Protein function

EGGNOG:0PN7DPGUG_03328glutaredoxin domain protein
SGD closest match:S000000218GRX7Monothiol glutaredoxin-7
CGD closest match:CAL0000192543orf19.4150Glutathione-disulfide reductase

Protein alignments

%idAln lengthE-value
A0A0J9XCN2_GEOCN58.68%1211e-47Similar to Saccharomyces cerevisiae YDL010W GRX6 Cis-golgi localized monothiol glutaredoxin that binds an iron-sulfur cluster OS=Geotrichum candidum GN=BN980_GECA10s02133g PE=4 SV=1
MIA_02753_138.65%2514e-45MIA_02753_1
A0A060T0G4_BLAAD56.31%1033e-40ARAD1C07502p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C07502g PE=4 SV=1
UniRef50_A0A060T0G456.31%1039e-37ARAD1C07502p n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A060T0G4_BLAAD
A0A1E3PPG4_9ASCO52.73%1105e-37Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46118 PE=4 SV=1
GLRX7_YEAST44.72%1234e-33Monothiol glutaredoxin-7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GRX7 PE=1 SV=1
A0A1E4TCR7_9ASCO49.51%1031e-33Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_13921 PE=4 SV=1
Q6C034_YARLI30.65%2488e-30YALI0F28127p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F28127g PE=4 SV=1
Q59NQ2_CANAL48.91%922e-26Glutathione-disulfide reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4150 PE=4 SV=1
A0A167DUM9_9ASCO32.43%1117e-12Dithiol glutaredoxin GRX2 OS=Sugiyamaella lignohabitans GN=GRX2 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2431

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 246

Detailed signature matches

  1. Domain IPR012336
    Thioredoxin-like fold
    1. SSF52833 (Thioredox...)
  2. Domain IPR002109
    Glutaredoxin
    1. PF00462 (Glutaredoxin)
    2. PS51354 (GLUTAREDOX...)
  3. Domain IPR014025
    Glutaredoxin subgroup
    1. PR00160 (GLUTAREDOXIN)
  4. Domain IPR011899
    Glutaredoxin, eukaryotic/virial
    1. TIGR02180
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.30.10
  3. NON_CYTOPLASM... (N...)
  4. SFLDG00328 (Glutare...)
  5. SIGNAL_PEPTIDE (Sig...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. SIGNAL_PEPTID... (S...)
  9. TMhelix
  10. cd03419 (GRX_GRXh_1...)
  11. mobidb-lite (disord...)

Residue annotation

  1. GSH binding site c...
  2. SFLDG00328
  3. catalytic residues...

Protein sequence

>MCA_05565_1
MITSRRSRAFLIAAILATVVFFLFSTSKVDPVQRQRLQQQEQAKQAHEQVKQQQQNNGDIDEIKEKVMMGNANNKAQQVN
NKPNAQGGVNSVVAPPKVNPQDSLNNQETEESATTTPFDAAKEYKLALKRSPIVIFSKSYCPHSKFAKNLFLKTYQVEPK
PYIVELDLHDHGSEFQDYLEEVTGRRTVPNIHIGGVTRGGADEFRDLESDGKVLETVEKWVKESKHVVPGNKKFSIVRNP
DAQVPN

GO term prediction

Biological Process

GO:0045454 cell redox homeostasis

Molecular Function

GO:0009055 electron carrier activity
GO:0015035 protein disulfide oxidoreductase activity

Cellular Component

None predicted.