Protein

MCA_05485_1

Length
402 amino acids

Gene name: ERG10A

Description: Acetyl-CoA acetyltransferase

Browser: contigD:1439124-1440493+

RNA-seq: read pairs 7746, FPKM 237.5, percentile rank 90.0% (100% = highest expression)

Protein function

Annotation:ERG10AAcetyl-CoA acetyltransferase
KEGG:K00626E2.3.1.9 acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
EGGNOG:0PG5VERG10Acetyl-CoA acetyltransferase
SGD closest match:S000005949ERG10Acetyl-CoA acetyltransferase
CGD closest match:CAL0000184591ERG10Acetyl-CoA C-acetyltransferase

Protein alignments

%idAln lengthE-value
MIA_00599_181.57%3690.0MIA_00599_1
S4SX03_GEOCN73.02%3670.0Acetyl-CoA acetyltransferase OS=Geotrichum candidum GN=Erg10 PE=2 SV=1
A0A161HK83_9ASCO72.48%3670.0Acetyl-CoA C-acetyltransferase OS=Sugiyamaella lignohabitans GN=ERG10 PE=3 SV=1
A0A1E3PKD4_9ASCO71.70%3710.0Acetyl-CoA c-acetyltransferase, cytosolic enzyme OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46480 PE=3 SV=1
Q6CFB6_YARLI69.57%3683e-180YALI0B08536p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B08536g PE=3 SV=1
UniRef50_A0A060N5L268.66%3672e-176Acetyl-CoA acetyltransferase n=23 Tax=cellular organisms TaxID=131567 RepID=A0A060N5L2_CYBJA
A0A060TDE5_BLAAD66.12%3692e-172ARAD1D47278p OS=Blastobotrys adeninivorans GN=AKAT4 PE=3 SV=1
A0A1D8PH52_CANAL67.09%3954e-170Acetyl-CoA C-acetyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ERG10 PE=3 SV=1
THIL_YEAST60.81%3706e-152Acetyl-CoA acetyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG10 PE=1 SV=3
A0A1E4TKV8_9ASCO60.00%3704e-148Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_970 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2984

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 402

Detailed signature matches

  1. Family IPR002155
    Thiolase
    1. TIGR01930
    2. cd00751 (thiolase)
    3. PIRSF000429 (Ac-CoA...)
  2. Domain IPR016039
    Thiolase-like
    1. SSF53901 (Thiolase-...)
    2. G3DSA:3.40.47.10
  3. Domain IPR020616
    Thiolase, N-terminal
    1. PF00108 (Thiolase_N)
  4. Domain IPR020617
    Thiolase, C-terminal
    1. PF02803 (Thiolase_C)
  5. SITE IPR020613
    Thiolase, conserved site
    1. PS00737 (THIOLASE_2)
  6. SITE IPR020610
    Thiolase, active site
    1. PS00099 (THIOLASE_3)

Residue annotation

  1. dimer interface cd...
  2. active site cd00751

Protein sequence

>MCA_05485_1
MPLGSPVYIVSAARTPIGGLLGSLSSLSYVDLGAHAVKAALDKVPQIKPTDVEEVVFGNVYGANLGQNPARQVAIKSGLG
IDTVATTVNKVCASGMKATIIGAQIILSGTADIVVTGGAESMSNVPHYLPDLRKGVKYGGSTVVDGMQKDGLQDAYDGQL
MGVAADLCADTHEFTREQQDDFAVTSYKRAQQAHNDGKFKAELAPVELPGVRGKPGVVVSTDEDAFKLNEERLRSARAVF
SKDGTVTAPNASSINDGGAALILMSAAKVKELGIQPIAQILGWGDAAHEPEKFTTAPSLAIPKALKHADIKIEDVDFFEF
NEAFSVVGLANCKILGIDTNKVNIYGGAVAIGHPLGCSGARVIVTLTSVLNQEGGKIGAAAICNGGGGASAIVIKKIDAS
KL

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups

Cellular Component

None predicted.