Protein

MCA_05460_1

Length
852 amino acids


Gene name: FRE3C

Description: Ferric reductase transmembrane component 3

Browser: contigD:1377004-1379586+

RNA-seq: read pairs 184, FPKM 2.7, percentile rank 13.1% (100% = highest expression)

Protein function

Annotation:FRE3CFerric reductase transmembrane component 3
EGGNOG:0PHSNFG01789.1Ferric-chelate reductase
SGD closest match:S000005908FRE3Ferric reductase transmembrane component 3
CGD closest match:CAL0000192959FRE3Fre3p

Protein alignments

%idAln lengthE-value
MIA_01964_150.15%6780.0MIA_01964_1
A0A0J9XIC4_GEOCN44.77%6500.0Similar to Saccharomyces cerevisiae YOR381W FRE3 Ferric reductase, reduces siderophore-bound iron prior to uptake by transporters OS=Geotrichum candidum GN=BN980_GECA19s01132g PE=4 SV=1
UniRef50_A0A0J9XIC444.77%6500.0Similar to Saccharomyces cerevisiae YOR381W FRE3 Ferric reductase, reduces siderophore-bound iron prior to uptake by transporters n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XIC4_GEOCN
Q6CF26_YARLI34.70%4875e-85YALI0B10846p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B10846g PE=4 SV=1
A0A1E3PIN1_9ASCO35.25%4889e-82Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83263 PE=4 SV=1
A0A167FY66_9ASCO34.90%4474e-76Fre2p OS=Sugiyamaella lignohabitans GN=FRE2 PE=4 SV=1
A0A060TAD4_BLAAD34.89%4071e-75ARAD1D26136p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D26136g PE=4 SV=1
A0A1D8PMF4_CANAL29.46%4481e-62Fre3p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=FRE3 PE=4 SV=1
A0A1E4TJY1_9ASCO30.63%4801e-60Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_81144 PE=4 SV=1
FRE3_YEAST30.84%4541e-58Ferric reductase transmembrane component 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FRE3 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2075

Protein family membership

None predicted.

Domains and repeats

1 100 200 300 400 500 600 700 800 852

Detailed signature matches

    1. PF05730 (CFEM)
    1. PF01794 (Ferric_reduct)
    1. SSF63380 (Riboflavi...)
    1. PS51384 (FAD_FR)
    1. PF08022 (FAD_binding_8)
    1. PF08030 (NAD_binding_6)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SFLDG01168 (Ferric_...)
  2. SFLDS00052 (Ferric_...)
  3. SSF52343 (Ferredoxi...)
  4. TRANSMEMBRANE (Tran...)
  5. cd06186 (NOX_Duox_l...)
  6. mobidb-lite (disord...)

Residue annotation

  1. FAD binding pocket...
  2. FAD binding motif ...
  3. beta-alpha-beta st...
  4. NAD pyrophosphate ...
  5. NAD binding pocket...
  6. NADP ribose bindin...

Protein sequence

>MCA_05460_1
MLNITSYLLLLLAPALIAAQKVGVASDKAFACWSASSEYNFGCNATDIKCLCQNTPFLETFSHCFRHRASDQKDINDGYV
YFYRQCYYNANISYTLGDMEDMNANCNNMLHSQKYNQTKIAGILAAAMIPTIQQKELESIKFASMQAAELLSSGTALPKS
PATATASTQTSSSASTNPTAPAHTSIILKVPVSIKDTEFEPQYKGAATVKYEYRIGSLYGSLLMGYWGLVIHPTSIPREV
LLANNRTANYIRKYLVLPATFRRHRSRPVKIFMDWYMCAPTRGQSILITMYIIFTIIALSINYNIYDENPVLPGASNQAL
KYLGVRTGIIAFTQLPLVIIFGSRNNPLIWSTGWPYDTFQVYHRWCARIMMLNVVIHSACFIAISVIGKTWVYRWEEIIN
WRFGNMATYAGIIMTVLAINRFRAKFYEAFFLAHKIFFIIFMIGIFRHCWDFGWMPWVYASLALYLSERFTRLFKLIVSG
FKNEAFAEVYSDGTFRLSVRYSRRWNVKPGQYCYVRVLTKNLFWQAHPFTVYKSPGEDANTLQFCIQAQKGATRKIADYL
AAQPEQCATLPVMIEGPYGVIQKIENYNSMFLIAGGLGITAVYSHALDLLQHGKKSHKVYVMWIIPNAVPLEWFSEELLS
LMHDSRFDIQIYITKAFSSNRSFSGDDSDEEMEEDFGSYNCEAIKSVDTTLDPRATPTSNSRVQGIPAPLPTVGFSRKSS
STTLHDKRSPLTDKHTFYKANFYESNVSVSTLGDSKNASSTALNKLKPTSSLSSQVVPAQRIRDQFAFCLFDKRPNINEE
IAKALMGTGTNGTMAIVSCGPPRLVDNIRASIVEHLMESEGRVEYFEEAFSW

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.