Protein
MCA_05264_1
Length
445 amino acids
Browser: contigD:798459-799797-
RNA-seq: read pairs 2645, FPKM 73.3, percentile rank 73.6% (100% = highest expression)
Protein function
KEGG: | K00147 | proA | glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] |
---|---|---|---|
EGGNOG: | 0PG7C | PGUG_02249 | gamma-glutamyl phosphate reductase |
SGD closest match: | S000005850 | PRO2 | Gamma-glutamyl phosphate reductase |
CGD closest match: | CAL0000189309 | PRO2 | Glutamate-5-semialdehyde dehydrogenase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_00112_1 | 75.45% | 444 | 0.0 | MIA_00112_1 |
A0A0J9X8B5_GEOCN | 66.59% | 440 | 0.0 | Similar to Saccharomyces cerevisiae YOR323C PRO2 Gamma-glutamyl phosphate reductase, catalyzes the second step in proline biosynthesis OS=Geotrichum candidum GN=BN980_GECA05s02353g PE=3 SV=1 |
A0A1E3PE09_9ASCO | 65.68% | 440 | 0.0 | Gamma-glutamyl phosphate reductase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47970 PE=3 SV=1 |
A0A167E692_9ASCO | 63.84% | 448 | 0.0 | Glutamate-5-semialdehyde dehydrogenase OS=Sugiyamaella lignohabitans GN=PRO2 PE=3 SV=1 |
Q6C421_YARLI | 66.36% | 434 | 0.0 | YALI0E30481p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E30481g PE=3 SV=1 |
A0A060TCJ4_BLAAD | 65.76% | 441 | 0.0 | ARAD1D36586p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D36586g PE=3 SV=1 |
PROA_YEAST | 61.67% | 454 | 0.0 | Gamma-glutamyl phosphate reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRO2 PE=1 SV=1 |
UniRef50_P54885 | 61.67% | 454 | 0.0 | Gamma-glutamyl phosphate reductase n=47 Tax=cellular organisms TaxID=131567 RepID=PROA_YEAST |
Q5ADR2_CANAL | 61.88% | 446 | 0.0 | Glutamate-5-semialdehyde dehydrogenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRO2 PE=3 SV=1 |
A0A1E4TJ54_9ASCO | 61.29% | 434 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30095 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0528
Protein family membership
- Glutamate-5-semialdehyde dehydrogenase (IPR012134)
Domains and repeats
-
Domain
-
Domain
1
50
100
150
200
250
300
350
400
445
Detailed signature matches
-
-
PIRSF000151 (GPR)
-
-
-
SSF53720 (ALDH-like)
-
-
-
PF00171 (Aldedh)
-
-
-
PS01223 (PROA)
-
no IPR
Unintegrated signatures
Residue annotation
-
putative catalytic...
Protein sequence
>MCA_05264_1 MSDAETIAQQARKASNILKTLSNEQRSNALQKIHDYLRDSKDEILAANKLDLEAAGTSNISQALVKRLDLTKGDKYDTML QGVLDVAALEDPVGKITLATKLDEGLDLYRVTAPVGVLLVIFESRPEVIANISALALKSGNAAILKGGKESTNTFKAMAK AVAQALASTGVVPEHGIQLITTREEVGELLKQDQYIDLVIPRGSNQLVRSIKDNTKIPVLGHADGICSIYISPDAQAEMA ARIVVDAKTNYPAGCNAVETLLIDQKVLSNEQTLKCVFDAILKAGVKLKVTPEIQVSLGKLGLEIKPDQVSPATEQDFYT EFLDLILAVKAVPSIDDAIEHINAHGSHHTDVIITDNEKDAEKFMKGVDSAGVYWNASSRFADGFRYGFGTEVGISTNKI HARGPVGLEGLVGYQYQLKGHGQVASDYLGAGGNKQFIHEPINTN
GO term prediction
Biological Process
GO:0006561 proline biosynthetic process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0004350 glutamate-5-semialdehyde dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding
Cellular Component
None predicted.