Protein

MCA_05154_1

Length
1,027 amino acids


Gene name: DBP10

Description: ATP-dependent RNA helicase DBP10

Browser: contigD:485344-488428-

RNA-seq: read pairs 1068, FPKM 12.8, percentile rank 30.7% (100% = highest expression)

Protein function

Annotation:DBP10ATP-dependent RNA helicase DBP10
KEGG:K14808DDX54 ATP-dependent RNA helicase DDX54/DBP10 [EC:3.6.4.13]
EGGNOG:0PHMJDBP10ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs (By similarity)
SGD closest match:S000002189DBP10ATP-dependent RNA helicase DBP10
CGD closest match:CAL0000186628DBP10ATP-dependent RNA helicase DBP10

Protein alignments

%idAln lengthE-value
A0A0J9XEA3_GEOCN58.70%9200.0Similar to Saccharomyces cerevisiae YDL031W DBP10 Putative ATP-dependent RNA helicase of the DEAD-box protein family OS=Geotrichum candidum GN=BN980_GECA11s03585g PE=4 SV=1
A0A167CX74_9ASCO56.95%9060.0Dbp10p OS=Sugiyamaella lignohabitans GN=DBP10 PE=4 SV=1
A0A060T4E8_BLAAD54.64%8840.0ARAD1B02904p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B02904g PE=4 SV=1
DBP10_YEAST48.99%8880.0ATP-dependent RNA helicase DBP10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DBP10 PE=1 SV=2
UniRef50_Q1238948.99%8880.0ATP-dependent RNA helicase DBP10 n=46 Tax=Saccharomycetales TaxID=4892 RepID=DBP10_YEAST
MIA_03811_164.30%5770.0MIA_03811_1
DBP10_YARLI51.15%5652e-165ATP-dependent RNA helicase DBP10 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=DBP10 PE=3 SV=1
DBP10_CANAL49.49%5842e-157ATP-dependent RNA helicase DBP10 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DBP10 PE=3 SV=1
A0A1E4TKT9_9ASCO43.06%5761e-123Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_42961 PE=4 SV=1
A0A1E3PEK3_9ASCO71.83%2521e-117DEAD-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83931 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0033

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 700 800 900 1027

Detailed signature matches

    1. SSF52540 (P-loop co...)
    1. PS51195 (Q_MOTIF)
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
    1. PF00270 (DEAD)
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
    1. SM01123 (DBP10CT_2)
    2. PF08147 (DBP10CT)
    1. PS00039 (DEAD_ATP_H...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00079 (HELICc)
  2. cd00268 (DEADc)
  3. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. Mg++ binding site ...
  3. motif III cd00268
  4. nucleotide binding...
  5. ATP-binding site c...

Protein sequence

>MCA_05154_1
MSDSESEIDISKAIGLDTGFSSSSDDSSSEDSDFYQDEIIDSSSDEEENEQEDNDDDNTKTEKKDSNNEILNINKDRLEK
IRQFENSAKSESTEEPVDLGKFPKLEMSDDDSDSDSDNNNSYNDNKTGKKRSRKDDDDDDDAFFNKLGVQAQGTKKKSIY
SFRGLGLSKLLCANVARRGFKMATPIQRKTIPYILEGRDVVGMARTGSGKTAAFVLPLLDRLKSHSATVGIRAIILSPSR
ELAEQTMRVVKEFSRGTDLRCALIVGGTSLDDQFKTMTNNPDIVIATPGRFLHLKIEMKLDLRSVQHIIFDEADRLFELG
FAEQLNEVLAALSRSRQTLLFSATLPKSLVEFAKAGLQDPVLLRLDAETKISEDLEMSYFAIKDGEREAALAYILGSVIK
MPIEKNLENRDKFKDEDYNSDDDEDDDDDDDDDENEDNENDKGKKKNKSKKGKKFEKWKKLPHRNELPSPYSTIVFTPTK
YHVEYIAQLLKALGYAVSYIYGALDQTARKDQLYKFRSGRTTVLVVTDVAARGIDIPVLANVINYSLPSSPKVFVHRVGR
TARAGNRGWAYSLIREMDIPYLLDLELFLGRKLLIPPKVIPNQRINYTERLVLGSFPREDLEQNMEEVDAIMKKDYDLSS
LRDVAKRGERQYLKSRESASQESSKRSKEILNTPGWDGRHPLFGTEDLEKERESFLEKLANRSNKDTVFEYKKTQFADVA
ELMQRRRQQIAPIRAKAEERKALQKKEAALGLVHTLDAEMFSDDEDDDQKKDLATEQELEKAFPEKNLNKGSSGSKKKKK
DYKDSNFYMSHYAAGSSAAEDRAYSINGGKTEFFGDAARNATFDLNEEGKEFVQKQGMKWDKKRGKYINAGSTGDKKSQQ
PIKYIRGENGTKIPASYRSGRYDAWREAHKAAPLRVGTAENPDGSNKVNFNAGVNQMPIGSGSGGGHPKHKKVVAPKRAD
KARDDYHKQRKKVSSALERGIKIKGKQPLYNGESEIHSVDEVRKARELLQKRREKNARPSKKKKTTR

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004004 ATP-dependent RNA helicase activity
GO:0005524 ATP binding

Cellular Component

GO:0005634 nucleus