Protein

MCA_05014_1

Length
885 amino acids

Browser: contigD:107433-110151+

RNA-seq: read pairs 1091, FPKM 15.2, percentile rank 34.5% (100% = highest expression)

Protein function

EGGNOG:0PIZ0FG04386.1XPG I-region
SGD closest match:S000000843YEN1Holliday junction resolvase YEN1
CGD closest match:CAL0000183527CAALFM_CR05010WACrossover junction endodeoxyribonuclease

Protein alignments

%idAln lengthE-value
MIA_00580_128.67%5864e-63MIA_00580_1
UniRef50_Q753T829.49%2957e-21AFR238Wp n=2 Tax=Saccharomycetaceae TaxID=4893 RepID=Q753T8_ASHGO
A0A0J9X4K0_GEOCN30.05%2133e-19Similar to Saccharomyces cerevisiae YER041W YEN1 Holliday junction resolvase OS=Geotrichum candidum GN=BN980_GECA01s10031g PE=4 SV=1
A0A1D8PSW4_CANAL25.17%2906e-19Crossover junction endodeoxyribonuclease OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR05010WA PE=4 SV=1
A0A161HFM5_9ASCO30.21%1924e-17Yen1p OS=Sugiyamaella lignohabitans GN=YEN1 PE=4 SV=1
Q6C4Y6_YARLI25.62%2039e-15YALI0E22671p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E22671g PE=4 SV=1
YEN1_YEAST24.33%3372e-14Holliday junction resolvase YEN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YEN1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0707

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 885

Detailed signature matches

  1. Family IPR006084
    XPG/Rad2 endonuclease
    1. PR00853 (XPGRADSUPER)
  2. Domain IPR029060
    PIN domain-like
    1. G3DSA:3.40.50...
    2. SSF88723 (PIN domai...)
  3. Domain IPR006086
    XPG-I domain
    1. SM00484 (xpgineu)
    2. PF00867 (XPG_I)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. NON_CYTOPLASM... (N...)
  4. TRANSMEMBRANE (Tran...)
  5. mobidb-lite (disord...)

Protein sequence

>MCA_05014_1
MGIKDLWDVIPNQYTELVPLSVFVQEHFDKQNGPPTIAVDAYVWYYEIKTAIEGANNRKPNKLNQDSPTYDTHALSQTVF
LNRMNSFISLGVILIMVFDGDRKIKKLRWNNGNSSCYPPVDRESSDWKNGISDIKLLCELCKVKIVNAPGEGEAECAYLF
ENGKVDYVFTSDSDVLMFGVTRIIKYAPKSIDLTLKSANSNSKSSKNEMKVSMKIPKNSKALDRYISVIRLPESDKSHFS
KESFILYALLRGGDHHFGSANIGSKLAEGLSFPKERFARDLLQIYKNNLEMARDDYKRCTDTRGMSLPELCSIEREMRDD
ILNEMLTELETNKSGYFSRKMSSNVNMTISNLLECLNEEIITYYLYPGNSSLIQWLKEKYEEVEIFAEEAAKAHVFFSDE
DIFRFDPAPGGGYPSQLRRLNRFWQANIKALWKITYVNYHWSAETFLKAIIPSFFPCVIFLDFPVFTVKSKRRYNQDGSS
LFFNPNLISNTLNPLDTSEHHPDALPTEISQFINFSRPEFYNVSLKPVDFFTSLKIPIDLTFFEEWGSNLKGDIEELLSK
AMTLQISGHLLKRCKYDYLARFAEKEKNNENGNTTNLNSNVISEAEVSIEDTVATPAKKSETFSKFEQLKRPITSLLPSK
ATKRGSGSLTSQKLKQSITKDQTSITSFFSTSHVASRSNSNAKAQTSITSFFSVSHDSLQTNSAKAPTLITKTVSDNEDT
LKQHISLKGNTPQSSKKRKLGIGSKSEIKEDVALEQTRKRFRMSNDDKNEQFVAKKFSSLPLVSKPPLTEDSSKVQKFPS
VPEETNEGLEIDSDEEFWKSMEDTLSRMSGTASNVNSSGYYSVVESSIKKENNNIKVESSRPSSKRKVRQDNDANDDTDA
DTDTE

GO term prediction

Biological Process

GO:0006281 DNA repair

Molecular Function

GO:0004518 nuclease activity

Cellular Component

None predicted.