Protein

MCA_04911_2

Length
444 amino acids

Gene name: CIT1B

Description: Citrate synthase, mitochondrial

Browser: contigC:4399253-4400588+

RNA-seq: read pairs 1075, FPKM 29.8, percentile rank 52.5% (100% = highest expression)

Protein function

Annotation:CIT1BCitrate synthase, mitochondrial
KEGG:K01647CS citrate synthase [EC:2.3.3.1]
EGGNOG:0PFD1citrate synthase
SGD closest match:S000005284CIT1Citrate synthase, mitochondrial
CGD closest match:CAL0000197786CIT1Citrate synthase

Protein alignments

%idAln lengthE-value
MIA_02982_184.84%4420.0MIA_02982_1
A0A0J9XBE6_GEOCN81.94%4430.0Citrate synthase OS=Geotrichum candidum GN=BN980_GECA08s00516g PE=3 SV=1
Q6C7I2_YARLI78.15%4440.0Citrate synthase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E00638g PE=3 SV=1
A0A060TI07_BLAAD77.06%4360.0Citrate synthase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D42504g PE=3 SV=1
A0A1E4TAC9_9ASCO73.92%4410.0Citrate synthase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3329 PE=3 SV=1
A0A167FS14_9ASCO79.95%3940.0Citrate synthase OS=Sugiyamaella lignohabitans GN=CIT1 PE=3 SV=1
UniRef50_A0A167FS1479.95%3940.0Citrate synthase n=18 Tax=Eukaryota TaxID=2759 RepID=A0A167FS14_9ASCO
A0A1E3PFJ1_9ASCO60.89%4730.0Citrate synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52511 PE=3 SV=1
CISY1_YEAST57.73%4401e-173Citrate synthase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CIT1 PE=1 SV=2
A0A1D8PSH3_CANAL56.52%4374e-170Citrate synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CIT1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7569

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 444

Detailed signature matches

  1. Family IPR002020
    Citrate synthase
    1. SSF48256 (Citrate s...)
    2. PF00285 (Citrate_synt)
    3. PR00143 (CITRTSNTHASE)
  2. Domain IPR016142
    Citrate synthase-like, large alpha subdomain
    1. G3DSA:1.10.58...
  3. Domain IPR016143
    Citrate synthase-like, small alpha subdomain
    1. G3DSA:1.10.23...
  4. SITE IPR019810
    Citrate synthase active site
    1. PS00480 (CITRATE_SY...)

Protein sequence

>MCA_04911_2
MIQKRSVSTLKEALKEVIPAKQELLKKVKTEYANKSLGDVKVENLLGGMRGLKAMLWEGSVLDAEEGIRFHGKTIKECQD
ILPKAPEGGEMLPESMLWLLLTGKVPSVDEVRQLSQQLAEDGELPDYAVKILDGLPAKTLHPMTQFAIAVSALNHDSKFA
KAYERGISKKEYWDYVFDDSLSLIAKLPQIAAKIYQNTYNGGGALPGKIDKSKDWAYNFAAQLGKEDKGGFVDLLRLYLA
LHGDHEGGNVSAHATHLVGSALSDPYLSYSAGLQGLAGPLHGLAAQEVLRFILDMQEKIPENYSDKDIEQYLWSVLNSGR
VIPGYGHAVLRKPDPRFQALMDFAKERPELLNDPTISLVLKNSEVAPKVLLEHGKTKNPHPNVDSASGALLHHYGITETL
FYTVTFGVSRALGPLPQLIWDRILGVPIERPKSLSLEKIIEIAK

GO term prediction

Biological Process

GO:0006099 tricarboxylic acid cycle

Molecular Function

GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

Cellular Component

None predicted.