Protein

MIA_02982_1

Length
457 amino acids

Browser: contig03:2252618-2254062-

Protein function

EGGNOG:0PFD1citrate synthase
SGD closest match:S000006205CIT3Citrate synthase 3, mitochondrial
CGD closest match:CAL0000197786CIT1Citrate synthase

Protein alignments

%idAln lengthE-value
A0A0J9XBE6_GEOCN83.514%4610.0Citrate synthase OS=Geotrichum candidum GN=BN980_GECA08s00516g PE=3 SV=1
Q6C7I2_YARLI81.938%4540.0Citrate synthase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E00638g PE=3 SV=1
A0A060TI07_BLAAD76.586%4570.0Citrate synthase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D42504g PE=3 SV=1
A0A1E4TAC9_9ASCO74.836%4570.0Citrate synthase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3329 PE=3 SV=1
A0A167FS14_9ASCO82.697%3930.0Citrate synthase OS=Sugiyamaella lignohabitans GN=CIT1 PE=3 SV=1
UniRef50_A0A167FS1482.697%3930.0Citrate synthase n=18 Tax=Eukaryota TaxID=2759 RepID=A0A167FS14_9ASCO
A0A1E3PFJ1_9ASCO60.417%4800.0Citrate synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52511 PE=3 SV=1
CISY3_YEAST53.165%4741.05e-175Citrate synthase 3, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CIT3 PE=1 SV=1
A0A1D8PSH3_CANAL56.422%4363.64e-174Citrate synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CIT1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9058
Predicted cleavage: 21

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 457

Detailed signature matches

  1. Family IPR002020
    Citrate synthase
    1. SSF48256 (Citrate s...)
    2. PF00285 (Citrate_synt)
    3. PR00143 (CITRTSNTHASE)
  2. Domain IPR016142
    Citrate synthase-like, large alpha subdomain
    1. G3DSA:1.10.58...
  3. Domain IPR016143
    Citrate synthase-like, small alpha subdomain
    1. G3DSA:1.10.23...
  4. SITE IPR019810
    Citrate synthase active site
    1. PS00480 (CITRATE_SY...)

Protein sequence

>MIA_02982_1
MYRPSARTLQTSFTAAQKRSVSTLKEALKEVIPAKVELFKKVKSEYSQKSLGEVKVENLLGGMRGLKAMLWEGSVLDANE
GIRFHGKTIKECQQILPKAKEGGEMLPESMLWLLLTGKVPSVEEAHQLSRQLAEAGELPEYASKLLDSLPNTLHPMTQFA
IAVSALNHDSKFAKAYEKGIPKNQYWEYTFDDSLDLIAKLPQIAAKIYQNTYLGGGALPGSIDLNRDWSYNYAAMIGKQD
ETGFIDLLRLYFALHGDHEGGNVSAHATHLVGSALSDPYLSYSAGLQGLAGPLHGLAAQEVLRFILDMKTNIPENYTDED
IKTYLWSVLNSGRVIPGYGHAVLRKPDPRFEALINFAKERPDVSSDPVVELVLRNSEVAPGVLLEHGKTKNPHPNVDSSS
GVLFHHYGITQTLYYTVTFGVSRALGPLPQLIWDRILGLPIERPKSLSLEKIIELAK

GO term prediction

Biological Process

GO:0006099 tricarboxylic acid cycle

Molecular Function

GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

Cellular Component

None predicted.