Protein
MCA_04881_1
Length
1,260 amino acids
Gene name: UBP2
Description: Ubiquitin carboxyl-terminal hydrolase 2
Browser: contigC:4330611-4334477-
RNA-seq: read pairs 2480, FPKM 24.3, percentile rank 46.8% (100% = highest expression)
Protein function
| Annotation: | UBP2 | Ubiquitin carboxyl-terminal hydrolase 2 | |
|---|---|---|---|
| KEGG: | K11849 | USP25 | ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12] |
| EGGNOG: | 0PGYH | UBP2 | ubiquitin carboxyl-terminal hydrolase |
| SGD closest match: | S000005650 | UBP2 | Ubiquitin carboxyl-terminal hydrolase 2 |
| CGD closest match: | CAL0000174377 | CAALFM_CR05980WA | Ubiquitin-specific protease |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03454_1 | 45.45% | 1252 | 0.0 | MIA_03454_1 |
| A0A060T713_BLAAD | 36.66% | 1173 | 0.0 | ARAD1B24112p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B24112g PE=3 SV=1 |
| UniRef50_A0A060T713 | 36.66% | 1173 | 0.0 | ARAD1B24112p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T713_BLAAD |
| A0A0J9X8Q9_GEOCN | 38.96% | 693 | 5e-131 | Similar to Saccharomyces cerevisiae YOR124C UBP2 Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins OS=Geotrichum candidum GN=BN980_GECA06s00318g PE=3 SV=1 |
| A0A1D8PT66_CANAL | 29.28% | 1110 | 1e-111 | Ubiquitin-specific protease OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR05980WA PE=3 SV=1 |
| UBP2_YEAST | 28.66% | 1092 | 8e-101 | Ubiquitin carboxyl-terminal hydrolase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UBP2 PE=1 SV=2 |
| A0A167ENJ7_9ASCO | 34.29% | 624 | 3e-86 | Ubp2p OS=Sugiyamaella lignohabitans GN=UBP2 PE=3 SV=1 |
| Q6CAE5_YARLI | 40.71% | 393 | 2e-74 | YALI0D03531p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D03531g PE=3 SV=1 |
| A0A1E3PMP0_9ASCO | 40.05% | 367 | 5e-70 | Cysteine proteinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_57578 PE=3 SV=1 |
| A0A1E4TE20_9ASCO | 38.46% | 364 | 2e-56 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_99732 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0075
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
200
400
600
800
1000
1260
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
SSF54001 (Cysteine ...)
-
cd02666 (Peptidase_...)
-
mobidb-lite (disord...)
Residue annotation
-
Active Site cd02666
Protein sequence
>MCA_04881_1 MANFAPPPIPPRPPKYDLQPCGRSSSSLVEEILRFEFGEHRLANDPIATSVGFPSGKPWNLSMYEEGLPIVRETETDIYL YALLHRNFGQPFFHLNIHIIKGSPLPPSEQNDFHLDQSQLQLDDVKEVYVFRCSITSTIVELTFRKPLFKSTDWSIYDIN AIMSRYHEFQHLNPEAVCPKQPACYQTLIKVIYKPLTESEMSTIDPQSFTVNVRVTPKFLIEKLHFTEDDSLIPPAIYEP ETEEQWQIRNEYIQKLHEVIMRFYHLFPGTNKNLYYLSPIDSTVRNILNDPKSPSNYTSPAYMNNVSNPLRSAYTVLGAT PEFTPEEILQRYNLQVVNDPKHRPYYFEAIKIIGQNQRSEVLEMKVAELMSLGEVSYSELSRAYNQFSLEYDSNVDYTLL IDTFKHMVMEYPAKESELRQALQLIAQYTDNDTLKDFLNDKTMSPEEAYTALGISSSSNDEFIHLAYETKMQEATNSEAE RALTALKTIAISRQSSILLSLYENAVKNDPTNEVNIPISVEEAHAFLGTSSDTPFDVLIASYKIRIEDNPKEILKFRKVL RTIGKSMKNQKIESFLSGAPDSDIVKNSELPVGLENIGNTCYLNSLLQFYFTINPLRNAVIDFLENSKNQKPSEIYKEKR VGGRVVSKEEIFRSRDFICALADLFKLLITTPSSSIAPSEKLAYLALVQPQIDPRMDEYKELVEEILTEHSQVNDKGKIS TNGSSNDSKTVQIRSETSTDNEGEVGNDTVIIHHIDSSSDGEHNEGDFDKDGDTEMISSADDSSNGNSKRSRSSIPSEAD SVICKRDRKDNEKGKEESVVTVKNIDSPTNSEKKKRMDDAIAIGGQQDVTECIENVLFQTECAFNATGVDEDGEQLDLIK ELFYGTTKQVIEDPTSGQIGESKTERFSMLIVNMEDKPQDIYDVMGTYFDDELVELGKKECIRHLTVTKLPPILQIQIQR VQFNKVTKQVYKSKAPVYLLDTIYLDRYLDTTDPVVLQKRKEIAEWKIQIAKLKKKLESMDKKLTAGLNTVDTLNLTADW LAMQNEAGEDIKVSTETISFLKRHTNQLQTKIKKIESKIKSLEEKVEYQFSGMKSAGYKLHSVFIHRGQASFGHYWIYIR DFKRGIYRVYNDKTISEVPESEVTGNEIKDPEATPYFVTYIREDLVDSLVDTVVRKIEVNDDDNESNDNHIAQIKNEDEH GSEDLIELSNSNSAAPPTPASLNEETTATVYSVSPPVDEKKDPSPALISLDDDEYPPLTR
GO term prediction
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016579 protein deubiquitination
Molecular Function
GO:0036459 thiol-dependent ubiquitinyl hydrolase activity
Cellular Component
None predicted.