MCA_04826_2
Gene name: VMA1
Description: V-type proton ATPase catalytic subunit A
Browser: contigC:4182407-4184530+
RNA-seq: read pairs 16555, FPKM 331.0, percentile rank 92.5% (100% = highest expression)
Protein function
| Annotation: | VMA1 | V-type proton ATPase catalytic subunit A | |
|---|---|---|---|
| KEGG: | K02145 | ATPeV1A | V-type H+-transporting ATPase subunit A [EC:3.6.3.14] |
| EGGNOG: | 0PH6V | VMA1 | vacuolar atp synthase catalytic subunit a |
| SGD closest match: | S000002344 | VMA1 | V-type proton ATPase catalytic subunit A |
| CGD closest match: | CAL0000187512 | TFP1 | V-type proton ATPase catalytic subunit A |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03720_1 | 89.97% | 618 | 0.0 | MIA_03720_1 |
| UniRef50_Q5AJB1 | 83.31% | 617 | 0.0 | V-type proton ATPase catalytic subunit A n=342 Tax=Eukaryota TaxID=2759 RepID=VATA_CANAL |
| VATA_CANAL | 83.31% | 617 | 0.0 | V-type proton ATPase catalytic subunit A OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TFP1 PE=1 SV=2 |
| A0A1E3PJX0_9ASCO | 81.36% | 617 | 0.0 | Vacuolar ATP synthase catalytic subunit A OS=Nadsonia fulvescens var. elongata DSM 6958 GN=VMA1 PE=3 SV=1 |
| A0A167DBW4_9ASCO | 86.14% | 577 | 0.0 | H(+)-transporting V1 sector ATPase subunit A OS=Sugiyamaella lignohabitans GN=VMA1 PE=3 SV=1 |
| Q6CHD8_YARLI | 80.07% | 612 | 0.0 | YALI0A09900p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A09900g PE=3 SV=1 |
| A0A060T2N6_BLAAD | 83.36% | 577 | 0.0 | ARAD1C29436p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C29436g PE=3 SV=1 |
| A0A0J9X536_GEOCN | 87.02% | 339 | 0.0 | Similar to Saccharomyces cerevisiae YDL185W VMA1 Subunit A of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase OS=Geotrichum candidum GN=BN980_GECA02s07754g PE=4 SV=1 |
| A0A1E4TBF3_9ASCO | 79.38% | 354 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_53321 PE=4 SV=1 |
| VATA_YEAST | 77.53% | 356 | 0.0 | V-type proton ATPase catalytic subunit A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VMA1 PE=1 SV=3 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.2591
Protein family membership
- V-type ATP synthase catalytic alpha chain (IPR022878)
- ATPase, V1 complex, subunit A (IPR005725)
Domains and repeats
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Domain
-
Domain
Detailed signature matches
no IPR
Residue annotation
-
Walker A motif/ATP...
-
Walker B motif cd0...
Protein sequence
>MCA_04826_2 MAGALENARKEIKNLSLDGISETQYGSIYSVSGPVVVAENMIGSAMYELVKVGHDNLVGEVIRIDGDKCTIQVYEETAGV TVGDPVLRTGKPLSVELGPGLMETIYDGIQRPLKAIQEKSQSIYIPRGVDAPALDRTVKYDFTPADFKVGDHITGGDIVG SVFENSLMTSHHILLPPKARGTITFIAEAGSYTVEETIVEVEFNGKKSSYSMFHTWPVREPRPVAERLSADYPLLTGQRV LDALFPVVQGGTTCIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMAEVLMEFPELFTVVEGRKEPIMKRTALVA NTSNMPVAAREASIYTGITIAEYFRDQGKDVAMIADSSSRWAEALREISGRLGEMPADQGFPAYLGAKLASFYERAGKAI AIGSPDRKGSVSIVAAVSPPGGDFSDPVTMSTLAITQVFWGLDKKLAQRKHFPSVNTSLSYSKYTNVLDKYYEKNYPEFP AFRNKVKEILSTAEELEQVVQLVGKSALSDSDKITLDVSNLIKDDFLQQNGYSTYDAFCPIWKTNAMLKAFVTYYEEAQK AVAAGAVWSRLAESTADIKHAVSSAKFFEPSLGEEELHKQFDKLQNDIVEKFAEAAE
GO term prediction
Biological Process
GO:0015991 ATP hydrolysis coupled proton transport
GO:0015992 proton transport
GO:0046034 ATP metabolic process
Molecular Function
GO:0005524 ATP binding
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Cellular Component
GO:0033180 proton-transporting V-type ATPase, V1 domain