MCA_04682_1

Protein

Length

1,036 amino acids

Gene name: GCV2

Description: Glycine dehydrogenase (decarboxylating), mitochondrial

Browser: contigC:3715233-3718344-

RNA-seq: read pairs 1074, FPKM 12.8, percentile rank 30.6% (100% = highest expression)

Protein function

Annotation:		GCV2	Glycine dehydrogenase (decarboxylating), mitochondrial
KEGG:	K00281	GLDC	glycine dehydrogenase [EC:1.4.4.2]
EGGNOG:	0PGZA	GCV2	glycine dehydrogenase
SGD closest match:	S000004801	GCV2	Glycine dehydrogenase (decarboxylating), mitochondrial
CGD closest match:	CAL0000198461	GCV2	Glycine cleavage system P protein

Protein alignments

	%id	Aln length
MIA_03894_1	79.67%	969	MIA_03894_1
A0A0J9X2V5_GEOCN	72.57%	966	Glycine cleavage system P protein OS=Geotrichum candidum GN=BN980_GECA01s10845g PE=3 SV=1
A0A1E3PGI4_9ASCO	69.14%	956	Glycine cleavage system P protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_26772 PE=3 SV=1
A0A167C0F7_9ASCO	67.36%	968	Glycine cleavage system P protein OS=Sugiyamaella lignohabitans GN=GCV2 PE=3 SV=1
A0A060T2A4_BLAAD	67.47%	959	Glycine cleavage system P protein OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A06710g PE=3 SV=1
Q6CHE0_YARLI	66.09%	976	Glycine cleavage system P protein OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A09856g PE=3 SV=1
A0A1E4TJZ4_9ASCO	63.04%	966	Glycine cleavage system P protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_675 PE=3 SV=1
UniRef50_Q09785	58.90%	1000	Putative glycine dehydrogenase (decarboxylating), mitochondrial n=109 Tax=cellular organisms TaxID=131567 RepID=GCSP_SCHPO
GCSP_YEAST	59.84%	981	Glycine dehydrogenase (decarboxylating), mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GCV2 PE=1 SV=1
A0A1D8PE97_CANAL	59.04%	979	Glycine cleavage system P protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GCV2 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9920
Predicted cleavage: 62

Protein family membership

Glycine cleavage system P protein (IPR020581)
- Glycine dehydrogenase (decarboxylating) (IPR003437)

Domains and repeats

Domain
78 - 509
Pyridoxal phosphate-dependent transferase (IPR015424)
527 - 963
Pyridoxal phosphate-dependent transferase (IPR015424)
1,008 - 1,031
Pyridoxal phosphate-dependent transferase (IPR015424)
Domain
164 - 413
Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (IPR015421)
414 - 514
Pyridoxal phosphate-dependent transferase, subdomain 2 (IPR015422)
602 - 848
Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (IPR015421)
849 - 981
Pyridoxal phosphate-dependent transferase, subdomain 2 (IPR015422)

1 100 200 300 400 500 600 700 800 900 1036

Detailed signature matches

IPR020581

Glycine cleavage system P protein
1. PF02347 (GDC-P)
  
  548 - 810
  
  Pfam
  PF02347 (GDC-P)
  
  77 - 512
  
  Pfam
  PF02347 (GDC-P)
2. cd00613 (GDC-P)
  
  132 - 512
  
  CDD
  cd00613 (GDC-P)
  
  558 - 949
  
  CDD
  cd00613 (GDC-P)
IPR003437

Glycine dehydrogenase (decarboxylating)
1. TIGR00461
  
  78 - 1,029
  
  TIGRFAMs
  TIGR00461 (TIGR00461)
2. MF_00711 (GcvP)
  
  69 - 1,035
  
  HAMAP
  MF_00711 (GcvP)
IPR015424

Pyridoxal phosphate-dependent transferase
1. SSF53383 (PLP-depen...)
  
  527 - 963
  
  SUPERFAMILY
  SSF53383 (PLP-dependent transferases)
  
  1,008 - 1,031
  
  SUPERFAMILY
  SSF53383 (PLP-dependent transferases)
  
  78 - 509
  
  SUPERFAMILY
  SSF53383 (PLP-dependent transferases)
IPR015421

Pyridoxal phosphate-dependent transferase, major region, subdomain 1
1. G3DSA:3.40.64...
  
  602 - 848
  
  GENE3D
  G3DSA:3.40.640.10 (G3DSA:3.40.640.10)
  
  164 - 413
  
  GENE3D
  G3DSA:3.40.640.10 (G3DSA:3.40.640.10)
IPR015422

Pyridoxal phosphate-dependent transferase, subdomain 2
1. G3DSA:3.90.11...
  
  414 - 514
  
  GENE3D
  G3DSA:3.90.1150.10 (G3DSA:3.90.1150.10)
  
  849 - 981
  
  GENE3D
  G3DSA:3.90.1150.10 (G3DSA:3.90.1150.10)

no IPR

Unintegrated signatures

Coil

705 - 725

COILS
Coil (Coil)
NON_CYTOPLASM... (N...)

47 - 1,036

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SIGNAL_PEPTIDE (Sig...)

1 - 46

PHOBIUS
SIGNAL_PEPTIDE (Signal Peptide)
SIGNAL_PEPTID... (S...)

39 - 46

PHOBIUS
SIGNAL_PEPTIDE_C_REGION (Signal peptide C-region)
SIGNAL_PEPTID... (S...)

27 - 38

PHOBIUS
SIGNAL_PEPTIDE_H_REGION (Signal peptide H-region)
SIGNAL_PEPTID... (S...)

1 - 26

PHOBIUS
SIGNAL_PEPTIDE_N_REGION (Signal peptide N-region)

Residue annotation

tetramer interface...

132E

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

133H

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

137A

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

138L

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

139L

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

142I

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

143A

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

144S

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

145K

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

146N

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

156G

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

158F

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

160T

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

161I

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

162T

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

163P

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

164P

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

167Q

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

170M

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

178T

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

179S

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

180Y

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

182P

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

183Y

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

184Q

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

186E

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

189Q

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

190G

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

191R

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

193E

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

221A

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

222A

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

232H

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

246I

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

247Y

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

248K

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

249Q

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

252T

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

253V

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

255E

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

256S

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

267V

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

297I

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

342Q

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

347P

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

348F

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

349G

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

350Y

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

351G

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

352G

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

353P

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

409Q

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

410A

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

411L

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

417A

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

421V

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

422Y

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

430D

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

433L

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

438L

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

440T

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

448E

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

457T

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

475K

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

498E

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

499T

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

502A

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)

503E

tetramer interface
132E, 133H, 137A, 138L, 139L, 142I, 143A, 144S, 145K, 146N, 156G, 158F, 160T, 161I, 162T, 163P, 164P, 167Q, 170M, 178T, 179S, 180Y, 182P, 183Y, 184Q, 186E, 189Q, 190G, 191R, 193E, 221A, 222A, 232H, 246I, 247Y, 248K, 249Q, 252T, 253V, 255E, 256S, 267V, 297I, 342Q, 347P, 348F, 349G, 350Y, 351G, 352G, 353P, 409Q, 410A, 411L, 417A, 421V, 422Y, 430D, 433L, 438L, 440T, 448E, 457T, 475K, 498E, 499T, 502A, 503E
CDD
cd00613 (GDC-P)
pyridoxal 5'-phosp...

155K

pyridoxal 5'-phosphate binding site
155K, 220T, 221A, 224E, 247Y, 249Q, 317A, 340N, 342Q, 343R
CDD
cd00613 (GDC-P)

220T

pyridoxal 5'-phosphate binding site
155K, 220T, 221A, 224E, 247Y, 249Q, 317A, 340N, 342Q, 343R
CDD
cd00613 (GDC-P)

221A

pyridoxal 5'-phosphate binding site
155K, 220T, 221A, 224E, 247Y, 249Q, 317A, 340N, 342Q, 343R
CDD
cd00613 (GDC-P)

224E

pyridoxal 5'-phosphate binding site
155K, 220T, 221A, 224E, 247Y, 249Q, 317A, 340N, 342Q, 343R
CDD
cd00613 (GDC-P)

247Y

pyridoxal 5'-phosphate binding site
155K, 220T, 221A, 224E, 247Y, 249Q, 317A, 340N, 342Q, 343R
CDD
cd00613 (GDC-P)

249Q

pyridoxal 5'-phosphate binding site
155K, 220T, 221A, 224E, 247Y, 249Q, 317A, 340N, 342Q, 343R
CDD
cd00613 (GDC-P)

317A

pyridoxal 5'-phosphate binding site
155K, 220T, 221A, 224E, 247Y, 249Q, 317A, 340N, 342Q, 343R
CDD
cd00613 (GDC-P)

340N

pyridoxal 5'-phosphate binding site
155K, 220T, 221A, 224E, 247Y, 249Q, 317A, 340N, 342Q, 343R
CDD
cd00613 (GDC-P)

342Q

pyridoxal 5'-phosphate binding site
155K, 220T, 221A, 224E, 247Y, 249Q, 317A, 340N, 342Q, 343R
CDD
cd00613 (GDC-P)

343R

pyridoxal 5'-phosphate binding site
155K, 220T, 221A, 224E, 247Y, 249Q, 317A, 340N, 342Q, 343R
CDD
cd00613 (GDC-P)
catalytic residue ...

343R

catalytic residue
343R
CDD
cd00613 (GDC-P)
tetramer interface...

558E

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

559T

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

563R

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

564Y

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

565M

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

568L

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

569Q

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

570S

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

571K

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

572D

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

585C

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

587M

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

589L

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

590N

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

591A

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

592T

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

593T

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

596I

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

599T

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

605S

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

606I

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

607H

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

609F

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

610S

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

611P

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

613D

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

616K

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

617G

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

618Y

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

620E

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

646A

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

647A

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

657R

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

677A

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

678H

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

679G

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

680T

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

683A

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

684S

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

686A

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

687M

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

694A

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

733F

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

780H

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

786P

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

787H

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

788G

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

789G

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

790G

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

791G

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

792P

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

833S

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

834A

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

835S

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

841W

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

845K

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

846L

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

854T

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

857E

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

862N

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

864N

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

872P

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

884K

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

909K

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

935E

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

936S

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

939I

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)

940A

tetramer interface
558E, 559T, 563R, 564Y, 565M, 568L, 569Q, 570S, 571K, 572D, 585C, 587M, 589L, 590N, 591A, 592T, 593T, 596I, 599T, 605S, 606I, 607H, 609F, 610S, 611P, 613D, 616K, 617G, 618Y, 620E, 646A, 647A, 657R, 677A, 678H, 679G, 680T, 683A, 684S, 686A, 687M, 694A, 733F, 780H, 786P, 787H, 788G, 789G, 790G, 791G, 792P, 833S, 834A, 835S, 841W, 845K, 846L, 854T, 857E, 862N, 864N, 872P, 884K, 909K, 935E, 936S, 939I, 940A
CDD
cd00613 (GDC-P)
pyridoxal 5'-phosp...

584S

pyridoxal 5'-phosphate binding site
584S, 645G, 646A, 649E, 678H, 680T, 754D, 778N, 780H, 781K
CDD
cd00613 (GDC-P)

645G

pyridoxal 5'-phosphate binding site
584S, 645G, 646A, 649E, 678H, 680T, 754D, 778N, 780H, 781K
CDD
cd00613 (GDC-P)

646A

pyridoxal 5'-phosphate binding site
584S, 645G, 646A, 649E, 678H, 680T, 754D, 778N, 780H, 781K
CDD
cd00613 (GDC-P)

649E

pyridoxal 5'-phosphate binding site
584S, 645G, 646A, 649E, 678H, 680T, 754D, 778N, 780H, 781K
CDD
cd00613 (GDC-P)

678H

pyridoxal 5'-phosphate binding site
584S, 645G, 646A, 649E, 678H, 680T, 754D, 778N, 780H, 781K
CDD
cd00613 (GDC-P)

680T

pyridoxal 5'-phosphate binding site
584S, 645G, 646A, 649E, 678H, 680T, 754D, 778N, 780H, 781K
CDD
cd00613 (GDC-P)

754D

pyridoxal 5'-phosphate binding site
584S, 645G, 646A, 649E, 678H, 680T, 754D, 778N, 780H, 781K
CDD
cd00613 (GDC-P)

778N

pyridoxal 5'-phosphate binding site
584S, 645G, 646A, 649E, 678H, 680T, 754D, 778N, 780H, 781K
CDD
cd00613 (GDC-P)

780H

pyridoxal 5'-phosphate binding site
584S, 645G, 646A, 649E, 678H, 680T, 754D, 778N, 780H, 781K
CDD
cd00613 (GDC-P)

781K

pyridoxal 5'-phosphate binding site
584S, 645G, 646A, 649E, 678H, 680T, 754D, 778N, 780H, 781K
CDD
cd00613 (GDC-P)
catalytic residue ...

781K

catalytic residue
781K
CDD
cd00613 (GDC-P)

Protein sequence

>MCA_04682_1
MSGRSLLMASRISRLSRASILRSASPLAASSSTVTPFLHNASPALTSKIESRSFHISKASLLASPSSPLAPLDTFIRRHT
GTQGKDVQKMLETVGYKDMDSFIADVVPSDILFKRELDISPSTQNGGEGLAEHEATALLKSIASKNKIVKSFIGKGYFGT
ITPPVIQRNMLESPEWYTSYTPYQPEISQGRLESLINFQTVVSDLTGLPIANCSLLDEGTAAAEAVIMAFHHHKEKRKTF
YVDPNIYKQTLTVVESRAKLLGINLIVGLPPATSNPKEDYKDVLGAMIQYPAADGSISDWSKLSADLHEAGSLLTVASDL
LALTVLEAPASFGADIVFGNSQRFGVPFGYGGPHAAFFATSDHEMRKMPGRLIGKSKDRLGNPAYRLALQTREQHIRREK
ATSNICTAQALLANMAAMYAVYHGPKGLKDIALRVFTLTTALATGLKETEYTVSNETFFDTLTIKVPNADEILAKAVSEY
QINLAKVDDSTISVSLDETVSAEDMTKLFQLFGVKSSVEDVVASLDKSVDGKFVAVPSEFARKSDFLKHDVFNKYHTETE
LLRYMHNLQSKDISLANSMIPLGSCTMKLNATTEMIPITWPEFASIHPFSPLDQAKGYAELITDLEKDLANITGFDATSL
QPNSGAAGEYTGLRVIRAYLESIGQGHRNVCLIPVSAHGTNPASAAMAGMKVVAVKCTNKGELDLKDLVAKVEKHKDNLA
AAMITYPSTFGVFEPTFKKACEIIHEHGGQVYMDGANMNAQIGLTSPGDIGADVCHLNLHKTFCIPHGGGGPGVGPICVK
SHLQPFLPGHEVVPMSASTPKSIGSVSSAPWGSASILPISWTYIKLSGNKGLKTNTEMALLNANYIKAKLEPYYPILYTN
EKDKCAHEFILDVRPFKATTGVEAIDIAKRLQDYGFHAPTMSFPVPNTLMIEPTESESIAELDKFIEAMISIRKEIQEIE
DGKMPKTNNVLKNAPHSAYDVTISNDWNDRPYTREKAAFPLPYLKERKAWPAVARVDDTYGDLNLFCTCDPPSLEE

GO term prediction

Biological Process

GO:0006544 glycine metabolic process
GO:0006546 glycine catabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0004375 glycine dehydrogenase (decarboxylating) activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features