Protein
MCA_04471_1
Length
392 amino acids
Gene name: PAF1
Description: RNA polymerase II-associated protein 1
Browser: contigC:3130360-3131539-
RNA-seq: read pairs 1296, FPKM 40.7, percentile rank 60.6% (100% = highest expression)
Protein function
| Annotation: | PAF1 | RNA polymerase II-associated protein 1 | |
|---|---|---|---|
| KEGG: | K15174 | PAF1 | RNA polymerase II-associated factor 1 |
| EGGNOG: | 0PKD6 | FG07289.1 | conserved hypothetical protein |
| SGD closest match: | S000000483 | PAF1 | RNA polymerase II-associated protein 1 |
| CGD closest match: | CAL0000196860 | orf19.3613 | Uncharacterized protein |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01173_1 | 61.98% | 384 | 6e-133 | MIA_01173_1 |
| A0A0J9XDB3_GEOCN | 57.29% | 377 | 2e-126 | Similar to saccharomyces cerevisiae YBR279W PAF1 Component of the Paf1p complex involved in transcription elongation OS=Geotrichum candidum GN=BN980_GECA11s02419g PE=4 SV=1 |
| Q6C509_YARLI | 48.56% | 381 | 4e-93 | YALI0E22022p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E22022g PE=4 SV=1 |
| UniRef50_Q6C509 | 48.56% | 381 | 1e-89 | YALI0E22022p n=2 Tax=Yarrowia lipolytica TaxID=4952 RepID=Q6C509_YARLI |
| A0A167CNC6_9ASCO | 47.79% | 385 | 3e-88 | Paf1p OS=Sugiyamaella lignohabitans GN=PAF1 PE=4 SV=1 |
| A0A1E3PQE8_9ASCO | 41.28% | 390 | 2e-75 | RNA polymerase II-associated OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81977 PE=4 SV=1 |
| A0A060TFD5_BLAAD | 45.48% | 376 | 4e-75 | ARAD1D22286p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D22286g PE=4 SV=1 |
| A0A1E4TEY0_9ASCO | 34.64% | 407 | 3e-43 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_56867 PE=4 SV=1 |
| PAF1_YEAST | 30.89% | 327 | 5e-35 | RNA polymerase II-associated protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PAF1 PE=1 SV=1 |
| Q59Y36_CANAL | 30.54% | 429 | 3e-31 | Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3613 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0524
Protein family membership
- RNA polymerase II associated factor Paf1 (IPR007133)
Domains and repeats
None predicted.
Detailed signature matches
Protein sequence
>MCA_04471_1 MTSKPRQDYIARIRYQNDLPPPPCPPKLLDIPIDIQKLTSWAFLSDLVRKQPSNMDLDMDQGMPLDMATVPGIFDREDEG ECYPLDPLPQLDSKDAILLRDPSGDASSLRTQPNVSFLRRTEYISSEIVRQKSENRPSSQSKDEKAINPEAQLRAVEETF EAANVDLATLKHPKNKKLKAVESFAILPDFKQLDLTYLTVKMVNSASLSTLPEKHSDSAYSVSLFRPTSLETDEWMSFFV PSDQDSKKLKRKLDDPRDSNIIDEDDENENLYRFNHVRDYEMELVQNEKNFNDIAINFDDTSIEHTGEEGEERRPTAWFV PIAGKTNLKRRRVTEDQRQQVAEHNFSSIEFSLRELTAEESLARDNVRAEYDSVSYMTTNEAGQVLNDEDDD
GO term prediction
Biological Process
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0016570 histone modification
Molecular Function
None predicted.
Cellular Component
GO:0016593 Cdc73/Paf1 complex