Protein
MCA_04400_1
Length
610 amino acids
Gene name: RIB2
Description: Bifunctional protein RIB2
Browser: contigC:2893829-2895877-
RNA-seq: read pairs 1776, FPKM 35.9, percentile rank 57.8% (100% = highest expression)
Protein function
| Annotation: | RIB2 | Bifunctional protein RIB2 | |
|---|---|---|---|
| KEGG: | K14655 | RIB2 | tRNA pseudouridine32 synthase / 2,5-diamino-6-(5-phospho-D-ribitylamino)-pyrimidin-4(3H)-one deaminase [EC:5.4.99.28] |
| EGGNOG: | 0PHG6 | PGUG_03398 | Pseudouridine synthase |
| SGD closest match: | S000005427 | RIB2 | Bifunctional protein RIB2 |
| CGD closest match: | CAL0000193029 | orf19.3177 | Bifunctional DRAP deaminase/tRNA pseudouridine synthase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_04591_1 | 74.70% | 585 | 0.0 | MIA_04591_1 |
| A0A0J9XAC0_GEOCN | 72.00% | 600 | 0.0 | Similar to Saccharomyces cerevisiae YOL066C RIB2 Bifunctional enzyme with DRAP deaminase and tRNA:pseudouridine synthase activity OS=Geotrichum candidum GN=BN980_GECA05s06852g PE=4 SV=1 |
| A0A060SZ03_BLAAD | 61.59% | 565 | 0.0 | ARAD1A15862p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A15862g PE=4 SV=1 |
| A0A1E3PEH3_9ASCO | 62.21% | 569 | 0.0 | Pseudouridine synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53422 PE=4 SV=1 |
| A0A1D8PND6_CANAL | 58.33% | 588 | 0.0 | Bifunctional DRAP deaminase/tRNA pseudouridine synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3177 PE=4 SV=1 |
| Q6C1Z1_YARLI | 61.11% | 540 | 0.0 | YALI0F12199p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F12199g PE=4 SV=1 |
| UniRef50_A0A1X7RB66 | 56.62% | 574 | 0.0 | Similar to Saccharomyces cerevisiae YDL036C PUS9 Mitochondrial tRNA:pseudouridine synthase, catalyzes the formation of pseudouridine at position 32 in mitochondrial tRNAs n=1 Tax=Kazachstania saulgeensis TaxID=1789683 RepID=A0A1X7RB66_9SACH |
| RIB2_YEAST | 55.83% | 575 | 0.0 | Bifunctional protein RIB2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RIB2 PE=1 SV=1 |
| A0A167D3Y9_9ASCO | 66.40% | 369 | 1e-167 | Bifunctional DRAP deaminase/tRNA pseudouridine synthase RIB2 OS=Sugiyamaella lignohabitans GN=RIB2 PE=4 SV=1 |
| A0A1E4TM99_9ASCO | 56.17% | 413 | 7e-158 | Pseudouridine synthase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22508 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0056
Protein family membership
- Pseudouridine synthase, RluC/RluD (IPR006225)
Domains and repeats
-
Domain
-
Domain
1
100
200
300
400
500
610
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
cd01284 (Riboflavin...)
-
cd02557 (PseudoU_sy...)
-
mobidb-lite (disord...)
Residue annotation
-
probable active si...
-
catalytic motif cd...
-
Zn binding site cd...
Protein sequence
>MCA_04400_1 MSSPQEKSTTAPEPEQQQAHPRFKGSKKHPMPQDTPDPTAHPSVKGGLRDPHGFRVKRQATQARSTAPDYQAGQGPPQNA QGMVTIEEETVQGAKYVIEGPLRRVPAYYFTYLTFCKMRWRDRNLLDVFTTEFRDRDREYYKYAISEGLVSLNKKVATLD TIIRNGDQISHRTHKHEPPVTSRPIKIVYEDDELVVIDKPSGIPVHPTGRYRFNTVVMVMQHEMGKVVHPCNRLDRLTSG LMFLAKSGKAAEKMGAQLRDREVKKEYIARVKGEFPLGTYVVEEPLATVAPKVALNRVRADGKPAKTEFKRISYDGQTSI VRCRPYTGRTHQIRVHLQYLGYPIANDPLYSNEWVWGPELGKNGAGNDAEIEEKLNQIGRTQPAGSWINPVDYAKVDAEE TAKKASGEVLTGEKCDVCKTDLFSDPSSNDLDLWLHALNYSSLATENKWSYQTDFPEWALEPNRKFMELALEEARKCEGT TTAFSVGALLVKDGKILSTGYSRELPGNTHAEQCALEKYFAKNNGVREVPEGTELYTTMEPCSERLSGNLPCVDRILEAG TIKTVFVGVLEPDTFVSNNTGKKKLTDAGIEYIHIPGYEKEALEIATKKP
GO term prediction
Biological Process
GO:0001522 pseudouridine synthesis
GO:0009451 RNA modification
Molecular Function
GO:0003723 RNA binding
GO:0003824 catalytic activity
GO:0009982 pseudouridine synthase activity
Cellular Component
None predicted.