Protein
MCA_04161_1
Length
693 amino acids
Gene name: HDA3
Description: HDA1 complex subunit 3
Browser: contigC:2236677-2238759-
RNA-seq: read pairs 1383, FPKM 24.6, percentile rank 47.3% (100% = highest expression)
Protein function
| Annotation: | HDA3 | HDA1 complex subunit 3 | |
|---|---|---|---|
| EGGNOG: | 0PH40 | HDA3 | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events |
| SGD closest match: | S000006383 | HDA3 | HDA1 complex subunit 3 |
| CGD closest match: | CAL0000189420 | CAALFM_CR09490WA | Uncharacterized protein |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02343_1 | 57.58% | 679 | 0.0 | MIA_02343_1 |
| A0A0J9XD17_GEOCN | 44.19% | 697 | 7e-169 | Similar to Saccharomyces cerevisiae YPR179C HDA3 Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex OS=Geotrichum candidum GN=BN980_GECA08s03475g PE=4 SV=1 |
| UniRef50_A0A0J9XD17 | 44.19% | 697 | 1e-165 | Similar to Saccharomyces cerevisiae YPR179C HDA3 Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XD17_GEOCN |
| A0A167CYV7_9ASCO | 38.62% | 738 | 4e-142 | Hda3p OS=Sugiyamaella lignohabitans GN=HDA3 PE=4 SV=1 |
| A0A060T8D5_BLAAD | 38.66% | 670 | 2e-128 | ARAD1C36058p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C36058g PE=4 SV=1 |
| Q6C4B7_YARLI | 43.66% | 339 | 7e-85 | YALI0E28204p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E28204g PE=4 SV=1 |
| HDA3_YEAST | 34.50% | 487 | 4e-76 | HDA1 complex subunit 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HDA3 PE=1 SV=1 |
| A0A1E4TEH1_9ASCO | 25.19% | 655 | 1e-38 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31164 PE=4 SV=1 |
| A0A1D8PTZ2_CANAL | 42.55% | 188 | 1e-34 | Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR09490WA PE=4 SV=1 |
| A0A1E3PJI9_9ASCO | 27.51% | 378 | 2e-18 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50790 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0152
Protein family membership
- HDA1 complex subunit 2/3 (IPR021006)
- HDA1 complex subunit 3 (IPR026216)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
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mobidb-lite (disord...)
Protein sequence
>MCA_04161_1 MDLGRILDGTPEPPTIIPNFDLFTNGTLHPADTNVLRDYVLPVPMTPFQKQLTDDVVSLHYSDILNFYETGSLENQVLQH SMEHLYANTQLVATHPYLLVQHYLPPNLLLKDVPNKLAKESGKFQILVDFIELVRDKKMDIALVSRAGKSFDLIEALLLG KMINYKRYSGSYLRQNSKTYKKFSTIHLFPSSQLDSTYIGSERFDLVIAFDLSFDLADPHIKAVRTQSRPVGSPPAPVIR FIPYYSAEHIIYKFQELKTQDETLFMKRVVAAIVILRGRAGSLPVDLRPYYSLGMKFLLPWLSDPTNNHWPLPATPEIDI YSAEDVEKSLLTEVVLEPSRHLEDSMQEYSNNISETAKTSNGHAKSNGHTNHHHNGLSFPKSVLKYEEEHDLSHPNIHRS ICKESTDDDDFYQAKRLKREKYSPSAPETALSFLAPPEGSSPVKHTLTHKLIRRLDIAMRELSLKDTEIASHRAIAASRQ NQYEELLEDSGKLTHEINQLKEKLRVYERKSERYDSDIQKLNETITKQTDELEQAHKLIKSESPATTIQLDEQNKEMNTV KESLQKAEEKIKSLHSENDYIRSEYQQASSAATNSLNDVVDLKKENEALKAKLEIAMQNMRQLSFDEERKAFENKIKELT VKNKNLEQHMKRLIENERLNSTRSRYGIRNSNSSRRNNSPSISGGRRGSPATS
GO term prediction
Biological Process
GO:0016575 histone deacetylation
Molecular Function
None predicted.
Cellular Component
GO:0005634 nucleus
GO:0070823 HDA1 complex