Protein
MCA_04066_2
Length
177 amino acids
Gene name: SNX3
Description: Sorting nexin-3
Browser: contigC:1937371-1938191+
RNA-seq: read pairs 5641, FPKM 391.6, percentile rank 93.4% (100% = highest expression)
Protein function
| Annotation: | SNX3 | Sorting nexin-3 | |
|---|---|---|---|
| KEGG: | K17918 | SNX3_12 | sorting nexin-3/12 |
| EGGNOG: | 0PNAS | SNX3 | Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)) |
| SGD closest match: | S000005884 | SNX3 | Sorting nexin-3 |
| CGD closest match: | CAL0000191797 | SNX3 | Sorting nexin-3 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9XGB5_GEOCN | 90.41% | 146 | 4e-98 | Similar to Saccharomyces cerevisiae YOR357C SNX3 Sorting nexin required to maintain late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment OS=Geotrichum candidum GN=BN980_GECA15s00125g PE=4 SV=1 |
| A0A1E3PS44_9ASCO | 70.06% | 177 | 1e-90 | Putative sorting nexin Snx3 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_44786 PE=4 SV=1 |
| SNX3_YARLI | 81.46% | 151 | 9e-91 | Sorting nexin-3 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=SNX3 PE=3 SV=1 |
| UniRef50_Q6C2S9 | 81.46% | 151 | 2e-87 | Sorting nexin-3 n=78 Tax=Fungi TaxID=4751 RepID=SNX3_YARLI |
| A0A1E4TC57_9ASCO | 82.64% | 144 | 3e-88 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_28864 PE=4 SV=1 |
| MIA_02432_1 | 90.00% | 130 | 2e-82 | MIA_02432_1 |
| A0A060TAH4_BLAAD | 84.50% | 129 | 2e-74 | ARAD1D19250p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D19250g PE=4 SV=1 |
| SNX3_CANAL | 60.90% | 156 | 3e-65 | Sorting nexin-3 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SNX3 PE=3 SV=2 |
| SNX3_YEAST | 56.93% | 137 | 2e-46 | Sorting nexin-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SNX3 PE=1 SV=1 |
| A0A167D465_9ASCO | 34.19% | 117 | 9e-14 | Snx4p OS=Sugiyamaella lignohabitans GN=SNX4 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0806
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
20
40
60
80
100
120
140
160
177
Detailed signature matches
no IPR
Unintegrated signatures
-
cd07295 (PX_Grd19)
-
mobidb-lite (disord...)
Residue annotation
-
phosphoinositide b...
Protein sequence
>MCA_04066_2 MTSNQVSSPTNKNTPESSKSRAFASIPDRPSNLSFEARPEIKQQTFDEIYGVPENFLEIEVRNPQTHGYGRKMYTDYEII CRTNIPAFKLKSSSVRRRYSDFECFRDILERETSRVTIPALPGKVFTNRFSDEVIENRREGLERFLQIVAGHPLLQTGSN ALAAFIQDPQWDKNQWI
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0035091 phosphatidylinositol binding
Cellular Component
None predicted.