Protein
MCA_04018_1
Length
586 amino acids
Gene name: MSL5
Description: Branchpoint-bridging protein
Browser: contigC:1781731-1783548+
RNA-seq: read pairs 2110, FPKM 44.4, percentile rank 62.7% (100% = highest expression)
Protein function
| Annotation: | MSL5 | Branchpoint-bridging protein | |
|---|---|---|---|
| KEGG: | K13095 | SF1 | splicing factor 1 |
| EGGNOG: | 0PFVG | BBP | Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns (By similarity) |
| SGD closest match: | S000004106 | MSL5 | Branchpoint-bridging protein |
| CGD closest match: | CAL0000178990 | BBP | Branchpoint-bridging protein |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9X9S3_GEOCN | 58.17% | 404 | 2e-141 | Similar to Saccharomyces cerevisiae YLR116W MSL5 Component of the commitment complex, which defines the first step in the splicing pathway OS=Geotrichum candidum GN=BN980_GECA07s00318g PE=4 SV=1 |
| UniRef50_A0A0J9X9S3 | 58.17% | 404 | 3e-138 | Similar to Saccharomyces cerevisiae YLR116W MSL5 Component of the commitment complex, which defines the first step in the splicing pathway n=5 Tax=saccharomyceta TaxID=716545 RepID=A0A0J9X9S3_GEOCN |
| MIA_01820_1 | 61.18% | 322 | 1e-123 | MIA_01820_1 |
| A0A1E3PT32_9ASCO | 58.93% | 336 | 1e-121 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45099 PE=4 SV=1 |
| A0A060T4S9_BLAAD | 56.29% | 334 | 1e-110 | ARAD1C06094p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C06094g PE=4 SV=1 |
| A0A167C7J2_9ASCO | 49.60% | 377 | 9e-103 | Msl5p OS=Sugiyamaella lignohabitans GN=MSL5 PE=4 SV=1 |
| BBP_YARLI | 49.06% | 373 | 1e-98 | Branchpoint-bridging protein OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=BBP PE=3 SV=1 |
| A0A1E4TH52_9ASCO | 53.62% | 304 | 2e-91 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_19902 PE=4 SV=1 |
| BBP_YEAST | 50.00% | 310 | 7e-87 | Branchpoint-bridging protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSL5 PE=1 SV=1 |
| BBP_CANAL | 41.06% | 302 | 1e-61 | Branchpoint-bridging protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BBP PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.3368
Predicted cleavage: 22
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Domain
1
100
200
300
400
500
586
Detailed signature matches
no IPR
Unintegrated signatures
-
PS50084 (KH_TYPE_1)
-
cd02395 (SF1_like-KH)
-
mobidb-lite (disord...)
Residue annotation
-
RNA binding site c...
-
G-X-X-G motif cd02...
Protein sequence
>MCA_04018_1 MSHRFDSKTGTNSVPLGKRRSDSHSVTASDMIFGNSSTSNDERLSHTDRRKKYRWNDASEENNILNAIKLTTQLSSPMTP EQLDAYALNFRIEEITIKLRFGDVVPKDRERSPSPTPQYDSQGKRTNTREVRYRTKLETERHKLIQRALKEIPNYKPPAD YKKPPKIQEKIFIPVDDFPGINFIGLLIGPRGHTLKKMESESGAKIAVRGKGSVKEGKGKADGPHQATMNENLHVLITAE EEHNLNKAIQLVNQVIETAASTPEEQNELKRGQLRELAALNGTLRNDDTNFCPICGDPGHRKIDCPSRKSYSNNIVCRFC GSAGHLSRDCKSRPSSGYGNSYRSNDTQNSMSNLAAEEEYHKLMQELGTDMPSSPSSQNRLRLTDSNHNKYNSNTNNQPR GGPAPWQQRNSNQGNNDSQWQNNHYENRGNYNNYNNRQGYDRGDRPNNYRNDRDRGDDYNNYSNNSNNYNNNNNYNNYNK NHHGYNNRYDNNDNYGRNQYNNNHHHQPPPPSRPQENIPPSHIPTQPAMHQLPAFSHVNKPAPPPGLSNIHPPGKGLPPP PPPPGKGRLPPPPPPGSARLPPPPPS
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0008270 zinc ion binding
Cellular Component
None predicted.