Protein
MCA_03950_1
Length
157 amino acids
Gene name: SEC11
Description: Signal peptidase complex catalytic subunit SEC11
Browser: contigC:1600470-1600944+
RNA-seq: read pairs 1505, FPKM 117.7, percentile rank 81.5% (100% = highest expression)
Protein function
| Annotation: | SEC11 | Signal peptidase complex catalytic subunit SEC11 | |
|---|---|---|---|
| KEGG: | K13280 | SEC11 | signal peptidase, endoplasmic reticulum-type [EC:3.4.-.-] |
| EGGNOG: | 0PJU3 | SEC11 | Catalytic component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum (By similarity) |
| SGD closest match: | S000001461 | SEC11 | Signal peptidase complex catalytic subunit SEC11 |
| CGD closest match: | CAL0000184794 | SEC11 | Signal peptidase complex catalytic subunit SEC11 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00074_1 | 71.52% | 151 | 9e-60 | MIA_00074_1 |
| A0A0J9X906_GEOCN | 70.95% | 148 | 1e-57 | Signal peptidase complex catalytic subunit SEC11 OS=Geotrichum candidum GN=BN980_GECA05s06258g PE=3 SV=1 |
| A0A060TC93_BLAAD | 63.58% | 151 | 9e-55 | Signal peptidase complex catalytic subunit SEC11 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D39864g PE=3 SV=1 |
| A0A1E3PH15_9ASCO | 63.16% | 152 | 6e-52 | Signal peptidase complex catalytic subunit SEC11 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83610 PE=3 SV=1 |
| UniRef50_A0A1X7RAV5 | 54.30% | 151 | 2e-40 | Similar to Saccharomyces cerevisiae YIR022W SEC11 18kDa catalytic subunit of the Signal Peptidase Complex n=1 Tax=Kazachstania saulgeensis TaxID=1789683 RepID=A0A1X7RAV5_9SACH |
| SEC11_YARLI | 54.97% | 151 | 2e-42 | Signal peptidase complex catalytic subunit SEC11 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=SEC11 PE=3 SV=1 |
| SEC11_CANAL | 56.08% | 148 | 3e-41 | Signal peptidase complex catalytic subunit SEC11 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SEC11 PE=3 SV=1 |
| SEC11_YEAST | 52.32% | 151 | 6e-41 | Signal peptidase complex catalytic subunit SEC11 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC11 PE=1 SV=2 |
| A0A1E4TJB4_9ASCO | 52.38% | 147 | 1e-35 | Signal peptidase complex catalytic subunit SEC11 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_42456 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.6330
Protein family membership
- Peptidase S26B (IPR001733)
Domains and repeats
-
Domain
1
20
40
60
80
100
120
140
157
Detailed signature matches
-
-
PS00501 (SPASE_I_1)
-
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
-
NON_CYTOPLASM... (N...)
-
TRANSMEMBRANE (Tran...)
-
cd06530 (S26_SPase_I)
Residue annotation
-
Catalytic site cd0...
Protein sequence
>MCA_03950_1 MIFPQLSIRQILGQVLNLCLVITTAFMFYKGLAVVSNSPSPIVVVLSGSMEPAFQRGDILFLWNRHNSEAPLSPEGKYTK SPTVNIGDIVVYNIKNRDIPIVHRVVRSHYSQKTNKQLLLTKGDNNPMDDLDLYAHKQMYLERNGEVVGSVKGIFLW
GO term prediction
Biological Process
GO:0006465 signal peptide processing
Molecular Function
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane