Protein
MCA_03891_1
Length
498 amino acids
Gene name: TRP3
Description: Multifunctional tryptophan biosynthesis protein
Browser: contigC:1424017-1425514-
RNA-seq: read pairs 2725, FPKM 67.5, percentile rank 71.8% (100% = highest expression)
Protein function
| Annotation: | TRP3 | Multifunctional tryptophan biosynthesis protein | |
|---|---|---|---|
| KEGG: | K01656 | TRP3 | anthranilate synthase / indole-3-glycerol phosphate synthase [EC:4.1.3.27 4.1.1.48] |
| EGGNOG: | 0PGPM | TRP1 | anthranilate synthase |
| SGD closest match: | S000001694 | TRP3 | Multifunctional tryptophan biosynthesis protein |
| CGD closest match: | CAL0000192837 | TRP3 | Bifunctional anthranilate synthase/indole-3-glycerol-phosphate synthase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01476_1 | 80.32% | 493 | 0.0 | MIA_01476_1 |
| A0A0J9X7T3_GEOCN | 77.27% | 484 | 0.0 | Similar to Saccharomyces cerevisiae YKL211C TRP3 Bifunctional enzyme exhibiting both indole-3-glycerol-phosphate synthase and anthranilate synthase activities OS=Geotrichum candidum GN=BN980_GECA04s06434g PE=4 SV=1 |
| A0A1E3PHT0_9ASCO | 71.07% | 484 | 0.0 | IGPS-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52140 PE=3 SV=1 |
| A0A170QZP3_9ASCO | 68.74% | 483 | 0.0 | Bifunctional anthranilate synthase/indole-3-glycerol-phosphate synthase OS=Sugiyamaella lignohabitans GN=TRP3 PE=3 SV=1 |
| Q6C9H7_YARLI | 68.05% | 482 | 0.0 | YALI0D11110p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D11110g PE=4 SV=1 |
| TRPG_YEAST | 65.26% | 498 | 0.0 | Multifunctional tryptophan biosynthesis protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TRP3 PE=1 SV=2 |
| UniRef50_P00937 | 65.26% | 498 | 0.0 | Multifunctional tryptophan biosynthesis protein n=38 Tax=Saccharomycetales TaxID=4892 RepID=TRPG_YEAST |
| A0A060TB89_BLAAD | 64.18% | 483 | 0.0 | ARAD1D33264p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D33264g PE=4 SV=1 |
| A0A1E4TFJ6_9ASCO | 59.96% | 487 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_106605 PE=3 SV=1 |
| A0A1D8PFC8_CANAL | 61.48% | 501 | 0.0 | Bifunctional anthranilate synthase/indole-3-glycerol-phosphate synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TRP3 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0466
Protein family membership
None predicted.
Domains and repeats
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Domain
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Domain
1
50
100
150
200
250
300
350
400
450
498
Detailed signature matches
no IPR
Unintegrated signatures
Residue annotation
-
glutamine binding ...
-
catalytic triad cd...
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ribulose/triose bi...
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active site cd00331
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phosphate binding ...
-
substrate (anthran...
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product (indole) b...
Protein sequence
>MCA_03891_1 MTEQAAKYYYTARVLMIDNYDSFTWNLYEYLCQEGAEVLVYRNDKITISEIEKLNPDMILISPGPGHPLHDSGISRDCIK HFAGKLPVIGVCMGQQCIYSVFGGIVEYAGEIVHGKTSTVTHDGKGLFENVSQGISVTRYHSLAGTQPSLPDELEVTART ENGGVIMGVRHKKYTIEGVQFHPESILTEEGHLMVRNILNIRGGTWEENDKLRKSNASSAASLKGNKEGSILDRIFEQRR QDVESQKSTPGKSFEDLKKSLDLGLAPAQIKDVVGRLKQSSPALMAEIKRASPSKGAIDLKAHAASQALTYAEGGASAIS ILTEPHWFKGSLDDLREVRMAIDKVENRPVVLRKEFIFDEYQILEARLAGADTVLLIVKMLDDKLLKQLYEYSLSLGMEP LVEVNSAEEMKRALALGSKLIGVNNRDLHSFNVDLNTTSSLVSLVPKDAVLAALSGISSGKDVAKYVSEGVSAILVGEAL MKAPDTKAFIKELISVKP
GO term prediction
Biological Process
GO:0006568 tryptophan metabolic process
GO:0008152 metabolic process
Molecular Function
GO:0003824 catalytic activity
GO:0004425 indole-3-glycerol-phosphate synthase activity
Cellular Component
None predicted.