Protein

MCA_03826_1

Length
742 amino acids

Gene name: PRP43B

Description: Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

Browser: contigC:1191403-1193764+

RNA-seq: read pairs 1077, FPKM 17.9, percentile rank 38.3% (100% = highest expression)

Protein function

Annotation:PRP43BPre-mRNA-splicing factor ATP-dependent RNA helicase PRP43
KEGG:K13117DHX35 ATP-dependent RNA helicase DDX35 [EC:3.6.4.13]
EGGNOG:0PG85FG01545.1RNA helicase
SGD closest match:S000003088PRP43Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43
CGD closest match:CAL0000191988orf19.1687DEAH-box ATP-dependent RNA helicase

Protein alignments

%idAln lengthE-value
MIA_05895_131.97%8579e-116MIA_05895_1
A0A0J9XHD3_GEOCN29.22%7535e-89Similar to Saccharomyces cerevisiae YGL120C PRP43 RNA helicase in the DEAH-box family OS=Geotrichum candidum GN=BN980_GECA16s02188g PE=4 SV=1
UniRef50_A0A0J9XHD329.22%7531e-85Similar to Saccharomyces cerevisiae YGL120C PRP43 RNA helicase in the DEAH-box family n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XHD3_GEOCN
A0A167CU84_9ASCO25.55%7674e-50DEAH-box ATP-dependent RNA helicase PRP22 OS=Sugiyamaella lignohabitans GN=PRP22 PE=4 SV=1
A0A1E4TFZ5_9ASCO24.03%7491e-43Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_108233 PE=4 SV=1
A0A060TB54_BLAAD24.54%6522e-42ARAD1B12958p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B12958g PE=4 SV=1
PRP43_YEAST24.36%7436e-40Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRP43 PE=1 SV=1
Q6C9M4_YARLI24.63%7473e-38YALI0D09955p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D09955g PE=4 SV=1
Q5AJA5_CANAL24.50%7472e-36DEAH-box ATP-dependent RNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1687 PE=4 SV=1
A0A1E3PNS0_9ASCO23.39%6541e-32ATP-dependent RNA helicase DHX8 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_40141 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0275

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 742

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR007502
    Helicase-associated domain
    1. SM00847 (ha2_5)
    2. PF04408 (HA2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:3.40.50...
  3. NON_CYTOPLASM... (N...)
  4. TRANSMEMBRANE (Tran...)

Protein sequence

>MCA_03826_1
MDDIELENSTKPYIKKLLKTLQTESIAIVVSSPLSDYTTEIPSSLLEYGWTLENQDPSFSSEVHVPSIAFSNPYTHHLKE
FAKRSLTPSAPGAESFSPGYRTGYSVPFSSVTSNITEIEYVQDRLLVDEISIDPIIRRRSVIIVDAIHQRTKWTDILLGL
LKSVLVYRNNPNTDKDRKRQLGITESTPLKLVLCLSPAYPQLVSQLQDFFKDFSDTGSENIQPIYAYTESYYNPAIDTFY
LSKQSSDFIASALDTLFYLFDEINSRNVDLDADILVFLPGKQHIEEFLKHAKSEYTGRYTSSKVLNDVGFQSLYEEDSLG
DTNLNLEEDISLIRVIACSSLAENYHLLLSSGRVCAVIDSGYDMMITPSNSLLAMKMYPISKGKAEIRRLMACKFASPNF
KAKCFRLYTKAWVNSMPNTETPELFSLFSITDDTIDTPLSDILLSLLSMRVKNIVSNFDFLPPVTQGAKAIENSYLYLFY
MGCITTTFELTPIGKIVAALKGVPIPLARSLAASISNENGSRICFDQLLSVAAMILAGGVLSVFNEPLAKSSQDRARTEH
ARFKAVQGDLITLLNIYQAFTENQSENWTRNRFLNYKALIKAQRIRVQLLLMINNVDDISNYRPSVKFPAVIVEKLLQCF
AKGYFLNAAKRTVSSETISEGGSLFHKDSGVRYQLLNNDDYEVRAHSKSVGSDEAISKNSSPWVIYTNITQYADNKWFIE
GVSTVERKWLTETKFYQEANLS

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0004386 helicase activity

Cellular Component

None predicted.