Protein
MCA_03808_1
Length
709 amino acids
Gene name: SPB4
Description: ATP-dependent rRNA helicase SPB4
Browser: contigC:1145741-1147943+
RNA-seq: read pairs 813, FPKM 14.1, percentile rank 32.7% (100% = highest expression)
Protein function
| Annotation: | SPB4 | ATP-dependent rRNA helicase SPB4 | |
|---|---|---|---|
| KEGG: | K14809 | DDX55 | ATP-dependent RNA helicase DDX55/SPB4 [EC:3.6.4.13] |
| EGGNOG: | 0PIRE | SPB4 | ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2 (By similarity) |
| SGD closest match: | S000001894 | SPB4 | ATP-dependent rRNA helicase SPB4 |
| CGD closest match: | CAL0000185825 | SPB4 | ATP-dependent rRNA helicase SPB4 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_05264_1 | 56.84% | 665 | 0.0 | MIA_05264_1 |
| A0A0J9XGA5_GEOCN | 52.92% | 582 | 0.0 | RNA helicase OS=Geotrichum candidum GN=BN980_GECA15s01143g PE=3 SV=1 |
| A0A167EIP6_9ASCO | 48.58% | 599 | 1e-170 | RNA helicase OS=Sugiyamaella lignohabitans GN=SPB4 PE=3 SV=1 |
| A0A1E3PH78_9ASCO | 47.43% | 603 | 1e-170 | RNA helicase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52397 PE=3 SV=1 |
| A0A060T4X7_BLAAD | 42.57% | 700 | 5e-152 | RNA helicase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C06644g PE=3 SV=1 |
| SPB4_YARLI | 43.56% | 606 | 1e-143 | ATP-dependent rRNA helicase SPB4 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=SPB4 PE=3 SV=1 |
| UniRef50_Q6C193 | 43.56% | 606 | 2e-140 | ATP-dependent rRNA helicase SPB4 n=3 Tax=Saccharomycetales TaxID=4892 RepID=SPB4_YARLI |
| SPB4_YEAST | 40.67% | 600 | 1e-131 | ATP-dependent rRNA helicase SPB4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPB4 PE=1 SV=1 |
| SPB4_CANAL | 41.42% | 606 | 1e-130 | ATP-dependent rRNA helicase SPB4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SPB4 PE=3 SV=1 |
| A0A1E4T9F7_9ASCO | 40.21% | 582 | 2e-123 | RNA helicase (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_14848 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.2126
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Domain
-
Domain
1
100
200
300
400
500
600
709
Detailed signature matches
no IPR
Unintegrated signatures
-
-
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cd00079 (HELICc)
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cd00268 (DEADc)
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mobidb-lite (disord...)
Residue annotation
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ATP binding site c...
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Mg++ binding site ...
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motif III cd00268
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nucleotide binding...
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ATP-binding site c...
Protein sequence
>MCA_03808_1 MSSRDWSSLNPPLSTWVLEAINTKGFTKMTPVQAAVIPLFRTNKDVIVQAVTGSGKTLAFLIPVIERILKLIDQDEEHIK PGQFNSIIISPTRELADQIYQVLQSILEFCPQDNTNNTYTKKKNRKKIRAQLVIGGDKSTSHSDVSIFMSRNPHIIVGTP GRLLELLKAPQTKLSALDNMVLDEADRLLELGFDNSVKTIIGMLPQQKRAGLFSATMSESVNDVARIGLRNPFQISVKVG LGKSAQQKQKEDANNEVVQAPKERRIPLSLGISYAITAPDQKIPLLLYILQNYSYKKTIVYFPTCLGVNYFYHLITYLIE QYDKIRRDQSTDDDSYEDFINARNIFFLHGKQISSVRKKTLEKFTTSMTSKSVLFTTDVAARGLDIPDVDLVLQLDPPVD HNVFLHRSGRAGRAGREGHSLVFLTNGKEEAYVDFMSVKMVDMTKYTFEPSKLPDIYTFNDSIEPEPAKAIQEKQKDEDK SDNENENEDEDEEKKNKQPIKAHNSKENIILEWMLRDRENFDMAVRAYVSYIRFYSKHRATSIFRLACLDYLGYAKAYGL FRLPAMPELKFIPEDEMPTDGWLVDPSIIDLDGYAYANEKKERERLAKIRKAEEERKKAIEQGLDPDEINKKKKKGKEIP LWAEQKMNAEKRREKRKLRHEAKYKNSIIDSDDEEAQKAMEVDWKDLVKERKSKKAKKATATTSAFDDL
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding
Cellular Component
None predicted.