Protein

MCA_03798_1

Length
455 amino acids

Gene name: VMA13

Description: V-type proton ATPase subunit H

Browser: contigC:1121275-1123132+

RNA-seq: read pairs 8511, FPKM 230.6, percentile rank 89.6% (100% = highest expression)

Protein function

Annotation:VMA13V-type proton ATPase subunit H
KEGG:K02144ATPeV1H V-type H+-transporting ATPase subunit H
EGGNOG:0PKVGVMA13vacuolar ATP synthase subunit H
SGD closest match:S000006240VMA13V-type proton ATPase subunit H
CGD closest match:CAL0000198653VMA13H(+)-transporting V1 sector ATPase subunit H

Protein alignments

%idAln lengthE-value
MIA_03664_171.49%4490.0MIA_03664_1
A0A0J9XGG6_GEOCN57.02%4561e-165Similar to Saccharomyces cerevisiae YPR036W VMA13 Subunit H of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) OS=Geotrichum candidum GN=BN980_GECA15s02012g PE=4 SV=1
A0A1E3PFK0_9ASCO46.14%4533e-134ATPase, V1 complex, subunit H OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_38165 PE=4 SV=1
A0A167FH48_9ASCO47.70%4572e-127H(+)-transporting V1 sector ATPase subunit H OS=Sugiyamaella lignohabitans GN=VMA13 PE=4 SV=1
UniRef50_A0A167FH4847.70%4577e-124H(+)-transporting V1 sector ATPase subunit H n=4 Tax=Saccharomycetales TaxID=4892 RepID=A0A167FH48_9ASCO
Q6C6K9_YARLI41.21%4612e-109YALI0E08617p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E08617g PE=4 SV=1
A0A060T8V2_BLAAD43.43%4261e-103ARAD1D05742p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D05742g PE=4 SV=1
A0A1E4TCN3_9ASCO37.25%4593e-81Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_28633 PE=4 SV=1
VATH_YEAST35.33%3175e-58V-type proton ATPase subunit H OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VMA13 PE=1 SV=1
A0A1D8PSX0_CANAL33.12%4804e-52H(+)-transporting V1 sector ATPase subunit H OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=VMA13 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2390

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 455

Detailed signature matches

  1. Family IPR004908
    ATPase, V1 complex, subunit H
    1. PIRSF032184 (V-ATP_...)
  2. Domain IPR016024
    Armadillo-type fold
    1. SSF48371 (ARM repeat)
  3. Domain IPR011989
    Armadillo-like helical
    1. G3DSA:1.25.10.10
  4. Domain IPR011987
    ATPase, V1 complex, subunit H, C-terminal
    1. PF11698 (V-ATPase_H_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.25.40...
  2. PF03224 (V-ATPase_H_N)

Protein sequence

>MCA_03798_1
MESHSALSTEFLDEIQKNILVRPIPWDGYVRASLLSTEDASLIKSIEKQHKVVEKNVEHVAQTFLTLIQTISREDVLKYL
LSLSASLLESIPEFAKAVLDLSEKDETFPYKPFVALLDKAQDIHLLAAKNLVILSSLKKAPSQYVLELFTFISTQLATPT
DPNLQEIAVLSFGLLLQPKWYRELFWTKSAEFVPPLVRILTTSRTNLQLQYHTLLVFWLLSFETVPAKEMVTKFDFVPIY
FDIIKNSVKEKIIRLAVALLVNISCPQSLALSTSQANSDKKPELTNQQKQQRRVAINSLLLNDGINMISTLCERKWADEE
LVADLTTLKQNLQEAFDSMTTFDEYKNELESKKLRWSPPHKSEGFWKENAEEFKAHDWKVLKALVDIIKSKPDDSTVNAV
AASDINHIFSLFPEAVKVVERIGGKVCIMELMADPSEEVRYEALKATQTLISNTL

GO term prediction

Biological Process

GO:0015991 ATP hydrolysis coupled proton transport

Molecular Function

GO:0005488 binding
GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
GO:0046961 proton-transporting ATPase activity, rotational mechanism

Cellular Component

GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain