Protein

MCA_03784_1

Length
340 amino acids

Browser: contigC:1072368-1073391-

RNA-seq: read pairs 1514, FPKM 54.9, percentile rank 67.3% (100% = highest expression)

Protein function

EGGNOG:0PPXNCatalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
SGD closest match:S000002303YDL144CUncharacterized protein YDL144C
CGD closest match:CAL0000195493orf19.2446Uncharacterized protein

Protein alignments

%idAln lengthE-value
MIA_05169_152.44%3287e-111MIA_05169_1
A0A0J9X5C9_GEOCN38.78%3122e-662-dehydropantoate 2-reductase OS=Geotrichum candidum GN=BN980_GECA03s04278g PE=3 SV=1
UniRef50_A0A0J9X5C938.78%3124e-632-dehydropantoate 2-reductase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X5C9_GEOCN
A0A060TD36_BLAAD34.76%3281e-592-dehydropantoate 2-reductase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D04070g PE=3 SV=1
A0A1E3PDX5_9ASCO31.79%3469e-486-phosphogluconate dehydrogenase C-terminal domain-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_44328 PE=4 SV=1
A0A167C5M4_9ASCO27.30%3488e-27Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_4049 PE=4 SV=1
Q5AA38_CANAL26.24%3432e-21Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2446 PE=4 SV=1
Q6C092_YARLI23.75%3419e-162-dehydropantoate 2-reductase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F26719g PE=3 SV=1
YD144_YEAST25.21%3493e-15Uncharacterized protein YDL144C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YDL144C PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7872
Predicted cleavage: 45

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 340

Detailed signature matches

  1. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  2. Domain IPR013332
    Ketopantoate reductase, N-terminal domain
    1. PF02558 (ApbA)
  3. Domain IPR013752
    Ketopantoate reductase, C-terminal domain
    1. PF08546 (ApbA_C)
  4. Domain IPR008927
    6-phosphogluconate dehydrogenase C-terminal domain-like
    1. SSF48179 (6-phospho...)
  5. Domain IPR013328
    6-phosphogluconate dehydrogenase, domain 2
    1. G3DSA:1.10.10...
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. NON_CYTOPLASM... (N...)
  3. SIGNAL_PEPTIDE (Sig...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)

Protein sequence

>MCA_03784_1
MSGSRILLIGAGAVGLVFASHILNNTQNVSLVILARSNYKVIRDKGFTINYPESDPPVTARYHVSHILEWSDETLLNYND
EPFDMVIISTKSLATEALPNLDRFMSPEKTLLILFQNGIEIERPYLERYPTIPLASAVIRVAASSDSLNAATVLPGGLRI
DIGLLKRFKDTPGCAEKLKLLESLCKEGNIARFDIVENIQVARWEKLLWNGSFNTVAAIVDKEVGPLINSKLQLVIRKLM
IEIWTVADAVLKSQGEEGWPSVSRVDELIEWTRNKVPANFVPSTLQDVRKNKPIESEAILGNVVRAAERENIKLSTIPAI
NSMLRSVNERILFIDKYLKI

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0008677 2-dehydropantoate 2-reductase activity
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding

Cellular Component

None predicted.