Protein
MCA_03646_1
Length
406 amino acids
Gene name: RAI1
Description: Decapping nuclease RAI1
Browser: contigC:645091-646312+
RNA-seq: read pairs 805, FPKM 24.4, percentile rank 47.0% (100% = highest expression)
Protein function
| Annotation: | RAI1 | Decapping nuclease RAI1 | |
|---|---|---|---|
| KEGG: | K14845 | RAI1 | RAT1-interacting protein |
| EGGNOG: | 0PIR0 | RAI1 | Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping and pyrophosphohydrolase activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates |
| SGD closest match: | S000003215 | RAI1 | Decapping nuclease RAI1 |
| CGD closest match: | CAL0000178137 | RAI1 | Decapping nuclease RAI1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03483_1 | 45.28% | 413 | 1e-128 | MIA_03483_1 |
| A0A1E3PCX4_9ASCO | 43.95% | 405 | 2e-106 | Putative suppressor of exonuclease defects OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53537 PE=4 SV=1 |
| UniRef50_A0A1E3PCX4 | 43.95% | 405 | 5e-103 | Putative suppressor of exonuclease defects n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A1E3PCX4_9ASCO |
| A0A0J9XEI3_GEOCN | 41.23% | 422 | 4e-105 | Similar to Saccharomyces cerevisiae YGL246C RAI1 Nuclear protein with decapping endonuclease activity targeted toward mRNAs with unmethylated 7-methylguanosine cap structures OS=Geotrichum candidum GN=BN980_GECA10s03013g PE=4 SV=1 |
| A0A060TD59_BLAAD | 40.15% | 406 | 3e-101 | ARAD1B21890p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B21890g PE=4 SV=1 |
| DXO_CANAL | 37.17% | 417 | 2e-83 | Decapping nuclease RAI1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RAI1 PE=1 SV=4 |
| DXO_YEAST | 34.84% | 419 | 4e-67 | Decapping nuclease RAI1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAI1 PE=1 SV=3 |
| DXO_YARLI | 33.67% | 392 | 8e-63 | Decapping nuclease RAI1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=RAI1 PE=3 SV=3 |
| A0A1E4TF94_9ASCO | 30.43% | 368 | 8e-55 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_13484 PE=4 SV=1 |
| A0A161HJC2_9ASCO | 36.54% | 156 | 7e-23 | Rai1p OS=Sugiyamaella lignohabitans GN=RAI1 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1252
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
406
Detailed signature matches
Protein sequence
>MCA_03646_1 MSKLSLDARSQNNGVKKPKELIVYSVDDDRNLYINSQNQLRYYYFPISEIKKKYDLKSGFDKFKIRDRSKPSHIDNLLKS IMYYEKNMNSGKRIKADFITFRGIMKSLMVLPYTRMNYPWYKCEGFIFNVKYFDGQIFLEIDHENFLKTQEKPGFKSKLD PKVYEYFGYKFETLASLSKPWAESSREEISNRDKKVVSNISEYCTIVRTGVGNFKTILGAEVDGIYDYSPKRRFPMKNQE DAAEIKELFDKKPSGSTDDLSHYVELKTQRGIYNDKDAKRFEIKLLSTWAQSFLVGTQHVVYGFRDDNGILQSVEEYKTD EVPRMVARSKFLEDESKWNGNECIAFYSAVLEWIKDTIPHDETQTWRLQYVPGETSLRLYRMNKEDEKRIGDFLLPEFVS WRKSLD
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.