Protein

MCA_03565_1

Length
157 amino acids

Gene name: ANB1

Description: Eukaryotic translation initiation factor 5A-2

Browser: contigC:363700-364624-

RNA-seq: read pairs 29850, FPKM 2334.4, percentile rank 98.0% (100% = highest expression)

Protein function

Annotation:ANB1Eukaryotic translation initiation factor 5A-2
KEGG:K03263EIF5A translation initiation factor 5A
EGGNOG:0PMXHTIF51Translation initiation factor
SGD closest match:S000003808ANB1Eukaryotic translation initiation factor 5A-2
CGD closest match:CAL0000197571ANB1Eukaryotic translation initiation factor 5A

Protein alignments

%idAln lengthE-value
A0A0J9XA14_GEOCN89.54%1536e-100Eukaryotic translation initiation factor 5A OS=Geotrichum candidum GN=BN980_GECA05s04586g PE=3 SV=1
A0A060T3Y9_BLAAD85.62%1534e-98Eukaryotic translation initiation factor 5A OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A13046g PE=3 SV=1
IF5A_CANAL84.97%1533e-96Eukaryotic translation initiation factor 5A OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ANB1 PE=3 SV=2
UniRef50_A0A0A1NA5382.17%1572e-91Eukaryotic translation initiation factor 5A n=7 Tax=Eukaryota TaxID=2759 RepID=A0A0A1NA53_9FUNG
IF5A2_YEAST81.17%1546e-92Eukaryotic translation initiation factor 5A-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ANB1 PE=1 SV=3
Q6CCS7_YARLI81.05%1535e-92Eukaryotic translation initiation factor 5A OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C06886g PE=3 SV=2
A0A1E3PJP0_9ASCO83.66%1531e-91Eukaryotic translation initiation factor 5A OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82569 PE=3 SV=1
A0A1E4TD66_9ASCO79.87%1542e-91Eukaryotic translation initiation factor 5A OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32883 PE=3 SV=1
A0A167E415_9ASCO85.29%1362e-84Eukaryotic translation initiation factor 5A OS=Sugiyamaella lignohabitans GN=ANB1 PE=3 SV=1
MIA_03802_179.26%1351e-76MIA_03802_1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0194

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 20 40 60 80 100 120 140 157

Detailed signature matches

  1. Family IPR001884
    Translation elongation factor IF5A
    1. PIRSF003025 (Transl...)
    2. TIGR00037
  2. Domain IPR014722
    Ribosomal protein L2 domain 2
    1. G3DSA:2.30.30.30
  3. Domain IPR008991
    Translation protein SH3-like domain
    1. SSF50104 (Translati...)
  4. Domain IPR012340
    Nucleic acid-binding, OB-fold
    1. SSF50249 (Nucleic a...)
  5. Domain IPR020189
    Translation elongation factor, IF5A C-terminal
    1. PF01287 (eIF-5a)
    2. SM01376 (eIF_5a_2)
  6. SITE IPR019769
    Translation elongation factor, IF5A, hypusine site
    1. PS00302 (IF5A_HYPUSINE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.40.50...
  2. cd04468 (S1_eIF5A)

Residue annotation

  1. RNA binding site c...

Protein sequence

>MCA_03565_1
MSDDHDHHFETASAGASATFPMQCSALRKNGHVVIKGRPCKIVDMSTSKTGKHGHAKVHLVAIDIFTGKKLEDLSPSTHN
MEVPNVTRTEYQLIDIDDGFLSLMTQDGATKDDIKLPEGELGSKIEADFNEGKDLLVTIISAMGEEAAISYKEAPKN

GO term prediction

Biological Process

GO:0006452 translational frameshifting
GO:0045901 positive regulation of translational elongation
GO:0045905 positive regulation of translational termination

Molecular Function

GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0043022 ribosome binding

Cellular Component

None predicted.