Protein

MCA_03304_1

Length
504 amino acids

Gene name: YNG2B

Description: Chromatin modification-related protein YNG2

Browser: contigB:3976760-3978355-

RNA-seq: read pairs 1026, FPKM 25.1, percentile rank 47.6% (100% = highest expression)

Protein function

Annotation:YNG2BChromatin modification-related protein YNG2
EGGNOG:0PJCWYNG2Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in cell cycle progression and meiosis
SGD closest match:S000001132YNG2Chromatin modification-related protein YNG2
CGD closest match:CAL0000174600YNG2Chromatin modification-related protein YNG2

Protein alignments

%idAln lengthE-value
MIA_03742_160.95%1695e-61MIA_03742_1
A0A0J9XJB4_GEOCN74.79%1191e-56Chromatin modification-related protein OS=Geotrichum candidum GN=BN980_GECA24s00890g PE=3 SV=1
UniRef50_A0A0J9XJB474.79%1192e-53Chromatin modification-related protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJB4_GEOCN
YNG2_YARLI65.35%1275e-54Chromatin modification-related protein YNG2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YNG2 PE=3 SV=1
A0A060TBQ3_BLAAD65.38%1308e-53Chromatin modification-related protein OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10274g PE=3 SV=1
A0A1E3PG82_9ASCO65.60%1253e-52Chromatin modification-related protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_26999 PE=3 SV=1
A0A167F864_9ASCO68.97%872e-36Chromatin modification-related protein OS=Sugiyamaella lignohabitans GN=YNG2 PE=3 SV=1
YNG2_CANAL49.59%1211e-33Chromatin modification-related protein YNG2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=YNG2 PE=3 SV=2
A0A1E4TJ02_9ASCO46.27%1349e-34Chromatin modification-related protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_75175 PE=3 SV=1
YNG2_YEAST62.69%672e-23Chromatin modification-related protein YNG2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YNG2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0843

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 504

Detailed signature matches

  1. Domain IPR024610
    Inhibitor of growth protein, N-terminal histone-binding
    1. PF12998 (ING)
    2. SM01408 (ING_2)
  2. Domain IPR013083
    Zinc finger, RING/FYVE/PHD-type
    1. G3DSA:3.30.40.10
  3. Domain IPR011011
    Zinc finger, FYVE/PHD-type
    1. SSF57903 (FYVE/PHD ...)
  4. Domain IPR001965
    Zinc finger, PHD-type
    1. SM00249 (PHD_3)
  5. Domain IPR019787
    Zinc finger, PHD-finger
    1. PS50016 (ZF_PHD_2)
  6. SITE IPR019786
    Zinc finger, PHD-type, conserved site
    1. PS01359 (ZF_PHD_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. cd15505 (PHD_ING)
  3. mobidb-lite (disord...)

Residue annotation

  1. H3K4me3 binding si...
  2. Zn binding site cd...

Protein sequence

>MCA_03304_1
MDAASILEQYVSDISNLPAEIAHILEEIRDKDLKFYEIRKRIQQRDNQIHKFIRTNGSLAENPKEQSAYPKIRNDFERAA
KLQNEKCDLAVLGLYAISKHLRKLQDKVKTLEDEGYVPPEEILTDHSKQLCEEISNHTINPTATTPIDFSILSEDLSEHN
PLLQSMLYAAQTSAVNGTGISPHQLQNGAINGHANGAIPSSTSASSLPSGYRNPAAALNHSLHQHLTNGGSAPNTPASSR
QVGGATSAGRGANGRHSRASTGGSQASHTRKHSTLAYSRSATPGNASSREGSVSDIGNGSASSNLTKEKSSGSTAANLAA
GSGSANNLNLTPTGRPSKRQKVGHGGAAAANQGASGTTKSSAGGSSGRQSVKVGSYASSRNATPSDDRGSNSAGATANTK
SRKSSSGSSATDAKHAASVDEALAGDSAEIDADTSIVQEGEDKVYCVCRQVSFGNMVACDNDECPYEWFHWDCVGLVEPP
QGTWYCPTCTKAMKEKETKKRSRS

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.