Protein

MCA_02876_1

Length
900 amino acids

Gene name: TRL1

Description: tRNA ligase

Browser: contigB:2586016-2588719-

RNA-seq: read pairs 920, FPKM 12.6, percentile rank 30.2% (100% = highest expression)

Protein function

Annotation:TRL1tRNA ligase
KEGG:K14679TRL1 tRNA ligase [EC:6.5.1.3]
EGGNOG:0PGIQPGUG_01548TRNA ligase
SGD closest match:S000003623TRL1tRNA ligase
CGD closest match:CAL0000175809LIG1tRNA ligase

Protein alignments

%idAln lengthE-value
MIA_04540_152.49%9220.0MIA_04540_1
A0A0J9X6B3_GEOCN46.38%9120.0tRNA ligase OS=Geotrichum candidum GN=BN980_GECA03s07006g PE=3 SV=1
UniRef50_A0A0J9X6B346.38%9120.0tRNA ligase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X6B3_GEOCN
A0A060SWM7_BLAAD39.66%8950.0tRNA ligase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A06358g PE=3 SV=1
A0A1E3PGS9_9ASCO40.57%9120.0tRNA ligase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_26810 PE=3 SV=1
A0A167F4M2_9ASCO41.06%8720.0tRNA ligase OS=Sugiyamaella lignohabitans GN=TRL1 PE=3 SV=1
TRNL_YEAST37.35%8623e-175tRNA ligase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TRL1 PE=1 SV=1
TRNL_CANAL35.80%8773e-159tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LIG1 PE=3 SV=2
Q6C923_YARLI33.62%9161e-153tRNA ligase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D14916g PE=3 SV=1
A0A1E4TDQ7_9ASCO33.17%8053e-134Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17595 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0670

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 900

Detailed signature matches

  1. Domain IPR019039
    RNA ligase T4 Rnl1, N-terminal
    1. PF09511 (RNA_lig_T4_1)
  2. Domain IPR015966
    tRNA ligase, kinase, fungi
    1. PF08303 (tRNA_lig_k...)
  3. Domain IPR015965
    tRNA ligase, phosphodiesterase, fungi
    1. PF08302 (tRNA_lig_CPD)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. mobidb-lite (disord...)

Protein sequence

>MCA_02876_1
MSSKLSAPFEVIQPKYPGKSLDLLFQELNQAAVSKSKRGKVRKNDYQLWTNPDIKITGWKYNEWDYGKESIKLAINARGL
FSYTDPKTSKESIVVRGYDKFFNINEVPMCNWDWIGENSKGPYYVTSKENGCIVFISGMEDGTLIVTSKQSTGPRLDSDQ
TEQDRASNHSYVSQKWVEKHLDSKGIDHKEFAKLLHSMNVTAVGELCDDSFEEHVLAYPSEEAGIYLHGLNVNVPTFTTY
PFEDVQKFAEKFGFRQTKYLVIQTIKELREFLEKCAETGTWNNKDVEGFVIRCKAKIPYTESGIDSGVEPSTACLDYFFK
YKFEEPYLMYRQWRELTKAFLSGTPRQDLSIKKNIYYTNLYLNYAIELLSKDTKLREDYLHNHGIIKVRQMFLDSIGCTG
SEIIQKEAEMSRENGEEELDENGNKKLKKQYVLVPVSTIGCGKTTIGIALTHLFPRWGHIQNDDIKKTPKPIHFARYCSD
VLKYATNTVAVFADRNNHKRAERKQLFTDMDSMRRPGTQNVYIGLNFRPDTSSEEKIWELTTKRVTNRGDNHQTIAASSD
DQYKVMGIMKGFVNRFQPVNTRASPDDQFDLVIDLDSTTENSSRTNLEIIVNKLYENYPELVPELPTKSDFDSAFKKALE
YKPEQLVTGKGGGSSEKKRNKLPSYFGIEINPLQSENSTNNTVETLTENLSGLSISESKNTTIPQLIDEFFKKNPEADTS
TWELLKKNKRVQETYHVTLVHKKQGNVNSNDKKAQEVYKRYQKIFESAPSDHSTDKKENTKKDSDGFQVVGKPNKNGNRY
LPGLEASVEIKKICWNNELMVFEVEIHSADSSSSDENLVETVNPVAHITIGTISPSIPAVKAGQALAGAKNSNSTGEKLT
KYEWNIEPKVLKSQKVAAYY

GO term prediction

Biological Process

GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation

Molecular Function

GO:0003972 RNA ligase (ATP) activity
GO:0005524 ATP binding

Cellular Component

None predicted.