MCA_02283_1
Gene name: RRP6
Description: Exosome complex exonuclease RRP6
Browser: contigB:798232-800746-
RNA-seq: read pairs 2044, FPKM 30.1, percentile rank 52.9% (100% = highest expression)
Protein function
| Annotation: | RRP6 | Exosome complex exonuclease RRP6 | |
|---|---|---|---|
| KEGG: | K12591 | RRP6 | exosome complex exonuclease RRP6 [EC:3.1.13.-] |
| EGGNOG: | 0PGUF | RRP6 | exosome complex exonuclease Rrp6 |
| SGD closest match: | S000005527 | RRP6 | Exosome complex exonuclease RRP6 |
| CGD closest match: | CAL0000183418 | RRP6 | Exosome nuclease subunit |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03953_1 | 50.35% | 862 | 0.0 | MIA_03953_1 |
| A0A0J9X9R2_GEOCN | 40.14% | 887 | 4e-180 | Similar to Saccharomyces cerevisiae YOR001W RRP6 Nuclear exosome exonuclease component OS=Geotrichum candidum GN=BN980_GECA05s03563g PE=4 SV=1 |
| UniRef50_A0A0J9X9R2 | 40.14% | 887 | 8e-177 | Similar to Saccharomyces cerevisiae YOR001W RRP6 Nuclear exosome exonuclease component n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X9R2_GEOCN |
| A0A167FUJ0_9ASCO | 45.55% | 595 | 6e-160 | Exosome nuclease subunit RRP6 OS=Sugiyamaella lignohabitans GN=RRP6 PE=4 SV=1 |
| A0A060T169_BLAAD | 45.02% | 582 | 5e-141 | ARAD1C22000p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C22000g PE=4 SV=1 |
| RRP6_YEAST | 42.64% | 523 | 2e-125 | Exosome complex exonuclease RRP6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RRP6 PE=1 SV=1 |
| A0A1D8PDF4_CANAL | 39.73% | 589 | 1e-124 | Exosome nuclease subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RRP6 PE=4 SV=1 |
| Q6C721_YARLI | 41.62% | 519 | 2e-116 | YALI0E04444p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E04444g PE=4 SV=1 |
| A0A1E3PRC2_9ASCO | 44.27% | 384 | 5e-97 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_80988 PE=4 SV=1 |
| A0A1E4TMD8_9ASCO | 41.67% | 384 | 6e-98 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11487 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.2120
Protein family membership
None predicted.
Domains and repeats
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Domain
Detailed signature matches
no IPR
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NON_CYTOPLASM... (N...)
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SIGNAL_PEPTIDE (Sig...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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cd06147 (Rrp6p_like...)
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mobidb-lite (disord...)
Residue annotation
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putative active si...
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catalytic site cd0...
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putative substrate...
Protein sequence
>MCA_02283_1 MDEKYKPLLSALQSTIRAASGVSSQDISFYRRLDKQLDKSSKKQSDRLLELANAIMGVAAKGEVEELVADENNDDLKENW DDVSIALDSLTQNIDLALLAHKKQLKKATDSVNNTDTLEANNMTKLSDPKSNEPVVSHHHEIAKPQLKFKIPVNNSKDNP FRPLLTEKPNAIVPFEESVKLIHPTEPDENGSLMRPYFPQPYEREILESEYPSSVYRHQPPIPSLPWNSTKPIWVDTPEK LEKMIESISDAKELAIDLEHHNYRSYLGITCLLQLSDRKNDYIIDAIALRTDLQPLNKIFTNPNIIKVLHGANMDIIWLQ RDLGLYIVSLFDTFYASKALNLKRNGLAYLLETYANFQTSKKYQLADWRIRPIPEEMLSYAQSDTHFLLNIYDKMKNQLV SDNRITEVLEQSRDVARRRFEIPGYDDEHYPRNNPFEKENSASQLALKNNLDRKQLVYLEHLMNWRDETARKLDESQSYL MPVHTLIALSTSMPTKSADIIKISGSHAHRLREHAKQLSLVMLEAKKIADSFQKDDSEALNEIDTSKSISIDYENSDDYE IYRENYEHLLEQQKKIFAPQHIEQIVRKFQNPISKLWGSTYESTASDESLIEHFPKGIFLYSAIVEPPQDETKTEDFKFE KTEDEPQENDDNVIFIGQSNKSQVLADESKDTKGEDFDSSQGNIELPSSAELIASQFNLLSKSQRKKLKRKMRKEAEAKE ELATDSTNIETSETSEQKRKREEESTDQLIEEDSSHSSASKKPKLESLPFNYDKAPSVLNRNNEEDGKKKKKKNKKKNKA FNPYGIIESEVKAPQKKEIHSAGVTKGSSISFKHEKN
GO term prediction
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006396 RNA processing
GO:0044237 cellular metabolic process
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003824 catalytic activity
GO:0008408 3'-5' exonuclease activity
Cellular Component
GO:0000176 nuclear exosome (RNase complex)
GO:0005622 intracellular