Protein

MCA_02220_1

Length
349 amino acids


Gene name: ADH3

Description: Alcohol dehydrogenase 3, mitochondrial

Browser: contigB:641502-642552+

RNA-seq: read pairs 144914, FPKM 5115.9, percentile rank 99.7% (100% = highest expression)

Protein function

Annotation:ADH3Alcohol dehydrogenase 3, mitochondrial
KEGG:K13953adhP alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
EGGNOG:0PH61ADH1alcohol dehydrogenase
SGD closest match:S000004688ADH3Alcohol dehydrogenase 3, mitochondrial
CGD closest match:CAL0000200753ADH2Alcohol dehydrogenase 2

Protein alignments

%idAln lengthE-value
MIA_04017_187.68%3490.0MIA_04017_1
A0A0J9XCP6_GEOCN85.14%3500.0Similar to Saccharomyces cerevisiae YMR083W ADH3 Mitochondrial alcohol dehydrogenase isozyme III OS=Geotrichum candidum GN=BN980_GECA10s00109g PE=3 SV=1
A0A167FJP5_9ASCO78.03%3464e-178Alcohol dehydrogenase ADH3 OS=Sugiyamaella lignohabitans GN=ADH3 PE=3 SV=1
A0A060TBM3_BLAAD77.75%3464e-175ARAD1B16786p OS=Blastobotrys adeninivorans GN=AADH1 PE=3 SV=1
UniRef50_A0A1V2L2I475.43%3462e-163Alcohol dehydrogenase 4, mitochondrial n=1 Tax=Cyberlindnera fabianii TaxID=36022 RepID=A0A1V2L2I4_CYBFA
ADH3_YEAST73.12%3462e-169Alcohol dehydrogenase 3, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADH3 PE=1 SV=2
Q6CGT5_YARLI72.78%3492e-165YALI0A16379p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A16379g PE=3 SV=1
A0A1E3PCI4_9ASCO72.25%3466e-164Alcohol dehydrogenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48354 PE=3 SV=1
ADH2_CANAL71.39%3466e-162Alcohol dehydrogenase 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ADH2 PE=3 SV=1
A0A1E4TA62_9ASCO66.76%3498e-151Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_126711 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0645

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 349

Detailed signature matches

    1. SSF50129 (GroES-like)
    1. SM00829 (PKS_ER_nam...)
    1. PF08240 (ADH_N)
    1. SSF51735 (NAD(P)-bi...)
    1. PF00107 (ADH_zinc_N)
    1. PS00059 (ADH_ZINC)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd08297 (CAD3)

Residue annotation

  1. catalytic Zn bindi...
  2. substrate binding ...
  3. NAD binding site c...
  4. tetramer interface...
  5. structural Zn bind...

Protein sequence

>MCA_02220_1
MSPIPKTQKAYVFEKNGGPLEYKDIPVPTPASDEILINVKYSGVCHTDLHAWKGDWPLPTKLPLVGGHEGAGVVVAKGEN
VTNFEIGEYAGIKWLNGSCLGCEYCLKSAESNCAQAILSGYTHDGSFQQYATAKAVHAAKIPQGTDLAKVAPILCAGITV
YKALKVADILAGEWVAITGAGGGLGTLAIQYAKAMGFRVLAIDTSDAKKEACLKLGAEAFVDFATTKDIVKEVQEVTKGG
PHAVIHVAVSEKALSISTEYVRPCGTIVLVGLPANAYVKSEVFSHVVKTINIKGSYVGNRADTAEAIDFFTRGLVEAPIK
IVGLSELESVYEKMEKGEIVGRYVLDTSK

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.