Protein

MCA_02103_1

Length
580 amino acids


Gene name: HSP60

Description: Heat shock protein 60, mitochondrial

Browser: contigB:248884-250627+

RNA-seq: read pairs 10145, FPKM 215.8, percentile rank 88.9% (100% = highest expression)

Protein function

Annotation:HSP60Heat shock protein 60, mitochondrial
KEGG:K04077groEL chaperonin GroEL
EGGNOG:0PHYRHSP60Heat shock protein
SGD closest match:S000004249HSP60Heat shock protein 60, mitochondrial
CGD closest match:CAL0000174464HSP60Heat shock protein 60, mitochondrial

Protein alignments

%idAln lengthE-value
MIA_05503_192.73%5500.0MIA_05503_1
A0A167DU91_9ASCO87.16%5450.0Chaperone ATPase HSP60 OS=Sugiyamaella lignohabitans GN=HSP60 PE=3 SV=1
A0A0J9XGJ2_GEOCN85.41%5550.0Similar to Saccharomyces cerevisiae YLR259C HSP60 Tetradecameric mitochondrial chaperonin required for ATP-dependent folding of polypeptides and complex assembly OS=Geotrichum candidum GN=BN980_GECA13s01880g PE=3 SV=1
Q6C342_YARLI84.71%5560.0YALI0F02805p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F02805g PE=3 SV=1
A0A060TF66_BLAAD87.05%5330.0ARAD1D20570p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D20570g PE=3 SV=1
A0A1E3PQ00_9ASCO81.44%5550.0Chaperonin GroL OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81832 PE=3 SV=1
HSP60_CANAL80.15%5440.0Heat shock protein 60, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HSP60 PE=3 SV=1
HSP60_YEAST77.88%5470.0Heat shock protein 60, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HSP60 PE=1 SV=1
UniRef50_P1988277.88%5470.0Heat shock protein 60, mitochondrial n=8004 Tax=root TaxID=1 RepID=HSP60_YEAST
A0A1E4TAM1_9ASCO79.42%5540.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_128919 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9325
Predicted cleavage: 27

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 580

Detailed signature matches

    1. PF00118 (Cpn60_TCP1)
    1. PR00298 (CHAPERONIN60)
    2. cd03344 (GroEL)
    3. MF_00600 (CH60)
    1. SSF52029 (GroEL api...)
    1. PS00296 (CHAPERONIN...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF48592 (GroEL equ...)
  2. SSF54849 (GroEL-int...)

Residue annotation

  1. ring oligomerisati...
  2. ATP/Mg binding sit...
  3. stacking interacti...
  4. hinge regions cd03...

Protein sequence

>MCA_02103_1
MQSALIKSSIRPSTVRSLASTSIRNYSLSSHKELKFGVEGRAALLKGVDTLAKAVSVTLGPKGRNVLIEQSFGAPKITKD
GVTVAKSITLQDKFENMGARLLQEVASKTNETAGDGTTSATVLGRSIFTESVKNVAAGCNPMDLRKGTQAAVEAVVEFLQ
KNKREITTSEEIAQVATISANGDSHIGKLISSAMEKVGKEGVITVKEGKTIEDELEVTEGMRFDRGYISPYFVTDAKSAK
VEFENPILLLSEKKISTLSDVLPALELSNKARRPLVIIAEDVDGEALAACILNKLRGQVQVAAVKAPGFGDNRKSILGDI
AILTGGTVFTEELDIKPENATMEQLGTSGAITITKEDTIILNGDGDKQNIVARCEQIRGYINDAHTSEYEKEKLQERLAK
LSGGVAVIRVGGSSEVEVGEKKDRFVDALNATRAAVEEGILPGGGTALIKASRVLDNVKTENFDQKLGVNIIRTACSKPV
RTIVENAGGEGSVIAGKLVDEFGEDFEKGYNAAAGEFTDMISAGIIDPFKVVRTGLVDAAGVASLLATTECAIVDAPAPP
PAAGAAPPMGGMGGMGGMGF

GO term prediction

Biological Process

GO:0006457 protein folding
GO:0042026 protein refolding

Molecular Function

GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm