Protein

MCA_01947_1

Length
633 amino acids

Gene name: DLD1B

Description: D-lactate dehydrogenase [cytochrome] 1, mitochondrial

Browser: contigA:5949173-5951075+

RNA-seq: read pairs 871, FPKM 17.0, percentile rank 36.9% (100% = highest expression)

Protein function

Annotation:DLD1BD-lactate dehydrogenase [cytochrome] 1, mitochondrial
KEGG:K00102LDHD D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4]
EGGNOG:0PGHWFG08715.1d-lactate dehydrogenase
SGD closest match:S000002333DLD1D-lactate dehydrogenase [cytochrome] 1, mitochondrial
CGD closest match:CAL0000191678orf19.6043Uncharacterized protein

Protein alignments

%idAln lengthE-value
MIA_04476_170.00%5200.0MIA_04476_1
A0A0J9X9H2_GEOCN67.61%4970.0Similar to Saccharomyces cerevisiae YDL174C DLD1 D-lactate dehydrogenase, oxidizes D-lactate to pyruvate,transcription is heme-dependent, repressed by glucose, and derepressed in ethanol or lactate OS=Geotrichum candidum GN=BN980_GECA06s04828g PE=4 SV=1
A0A167CKJ9_9ASCO63.67%5120.0Dld1p OS=Sugiyamaella lignohabitans GN=DLD1 PE=4 SV=1
UniRef50_A0A167CKJ963.67%5120.0Dld1p n=326 Tax=Fungi TaxID=4751 RepID=A0A167CKJ9_9ASCO
A0A060T9L5_BLAAD62.01%5080.0ARAD1D16016p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D16016g PE=4 SV=1
A0A1E3PLT7_9ASCO61.70%5170.0FAD-binding domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82226 PE=4 SV=1
Q6C773_YARLI54.78%5020.0YALI0E03212p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E03212g PE=4 SV=1
A0A1E4TKE1_9ASCO52.76%4896e-171Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_802 PE=4 SV=1
DLD1_YEAST42.28%4731e-115D-lactate dehydrogenase [cytochrome] 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DLD1 PE=1 SV=2
Q5ABC8_CANAL41.23%5362e-111Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6043 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9748
Predicted cleavage: 36

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 633

Detailed signature matches

  1. Domain IPR016167
    FAD-binding, type 2, subdomain 1
    1. G3DSA:3.30.43.10
  2. Domain IPR016166
    FAD-binding, type 2
    1. PS51387 (FAD_PCMH)
    2. SSF56176 (FAD-bindi...)
  3. Domain IPR006094
    FAD linked oxidase, N-terminal
    1. PF01565 (FAD_binding_4)
  4. Domain IPR016169
    CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2
    1. G3DSA:3.30.46...
  5. Domain IPR016164
    FAD-linked oxidase-like, C-terminal
    1. SSF55103 (FAD-linke...)
  6. Domain IPR004113
    FAD-linked oxidase, C-terminal
    1. PF02913 (FAD-oxidase_C)
  7. Domain IPR016171
    Vanillyl-alcohol oxidase, C-terminal subdomain 2
    1. G3DSA:1.10.45.10
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TRANSMEMBRANE (Tran...)

Protein sequence

>MCA_01947_1
MLKNYRTLLPSINKRISNNQYIYRLQTQPSSVVRYASSSSSTTGSAASSSSNDGDEFKYKSSKGLFFECVRIGSVAAVAS
LGTFYFLHNSYYNDPSKLHSESINKNWTERKYGGRKEFDHAYPEFEKLLGDRVTTDDDELRRHGYSEWCSLKIPPNLTPI
AVAYPKTTEEVSNIAKLCHKYRLPMIGYSGGSSLEGNFTAPYGGICIDFSLMNKIIKVRPEDMDATVQPGVGWMDLNGQL
KKEGLNLFLPVDPGPIAKIGGMVSTSCSGTNCVRYGPMRNWIVNLTVVLADGSIIKTRGRPRKSSAGYNLNHLFAGSEGT
LGLITEITVKLDVVPEKTSIALCPFPTIRDATDTAIDIIRAGIPVHCVELMDEVQMWAINNSGYTKRKWDEQSTLFFKFS
GSPAYIEEQVSKAKKIAASHGSNKFIFAKTEEEGNEIWAARKESLWHSLALAPTGSENYATDVAVPMSKLADLIEDSKRD
LINSGIAFGTSMGHVGDGNFHAGLIYNPETEKDIAGKVAENINYRGLALEGTCSGEHGIGVGKVDYLVGELGTDVINLMH
TIKIALDPLELLNPGKVFTKAAIERGLEQEKNGTWGGKNFNFHKFEESDERRSILEILEERRLKQKQATEHTA

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0050660 flavin adenine dinucleotide binding

Cellular Component

None predicted.