Protein

MCA_01864_1

Length
125 amino acids


Gene name: PFY1

Description: Profilin

Browser: contigA:5721034-5721879+

RNA-seq: read pairs 12495, FPKM 1225.3, percentile rank 97.0% (100% = highest expression)

Protein function

Annotation:PFY1Profilin
KEGG:K05759PFN profilin
EGGNOG:0PQR4PFY1Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity)
SGD closest match:S000005648PFY1Profilin
CGD closest match:CAL0000200755PFY1Profilin

Protein alignments

%idAln lengthE-value
A0A0J9X598_GEOCN71.20%1252e-60Profilin OS=Geotrichum candidum GN=BN980_GECA03s00923g PE=3 SV=1
UniRef50_A0A1V2L4N162.70%1268e-47Profilin n=1 Tax=Cyberlindnera fabianii TaxID=36022 RepID=A0A1V2L4N1_CYBFA
A0A060T3S8_BLAAD61.90%1262e-52Profilin OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C39402g PE=3 SV=1
W0TYP0_YARLI59.52%1261e-50Profilin OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B07183g PE=3 SV=1
A0A1E3PM99_9ASCO59.52%1266e-50Profilin OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50487 PE=3 SV=1
Q5A786_CANAL58.73%1261e-49Profilin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PFY1 PE=3 SV=1
PROF_YEAST55.56%1261e-49Profilin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PFY1 PE=1 SV=2
MIA_02413_142.40%1251e-33MIA_02413_1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0291

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. PF00235 (Profilin)
    2. SM00392 (prof_2)
    3. PR00392 (PROFILIN)
    4. cd00148 (PROF)
    5. SSF55770 (Profilin ...)
    6. PR01640 (PROFILINPLNT)
Unintegrated signatures no IPR
Unintegrated signatures

Residue annotation

  1. poly-proline bindi...
  2. actin interaction ...
  3. putative PIP2-inte...

Protein sequence

>MCA_01864_1
MSWLGYVDSLKAAGLDQAAIYSKAGDSVWAQSDGFNISASEIQELVKGFDNPSGLQASGLHIQGQKYFLLRADERSIYGK
YEDTGIIAVKTNLAIIIAHYGPSIQAGSAATAVEKVADHLIKLNY

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.